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Bioinformatics

The document discusses how artificial intelligence can be used in biology and bioinformatics. Specifically, it notes that AI is well-suited for analyzing large datasets in fields like genetics and medicine. It provides examples of how AI is being used to analyze gene expressions to detect diseases and improve medicine. The document also discusses CRISPR gene editing technology and how AI can help scientists analyze the effects of alterations without running all possible experimental tests.

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269 views10 pages

Bioinformatics

The document discusses how artificial intelligence can be used in biology and bioinformatics. Specifically, it notes that AI is well-suited for analyzing large datasets in fields like genetics and medicine. It provides examples of how AI is being used to analyze gene expressions to detect diseases and improve medicine. The document also discusses CRISPR gene editing technology and how AI can help scientists analyze the effects of alterations without running all possible experimental tests.

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© © All Rights Reserved
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FRIDAY, 02/16/18

AI & BIOINFORMATICS
WHY USE AI IN BIOLOGY?
▸ The field of biology is still growing, and scientists are
trying to learn more about genetics and disease.

▸ Research in fields such as medicine and genetics involves


a lot of data

▸ There is too much information for humans to analyze


on their own.

▸ AI is good at analyzing and learning from large amounts of


data

▸ AI’s are able to find accurate trends and patterns, as


well as predict results.
BIOINFORMATICS
‣ Interdisciplinary field

‣ Computer science

‣ Biology

‣ Mathematics

‣ Used in

‣ Genetics and genomics

‣ Molecular biology
GENETICS AND MEDICINE
▸ Human genome is comprised of 3
billion base pairs

▸ DNA is subject to mutations, which


can cause diseases, such as:
▸ Cancer
▸ Sickle Cell Anemia
▸ Cystic Fibrosis

▸ Scientists are now using AI to


detect these diseases, improve
medicine, and find cures by
analyzing gene expressions.
TECHNIQUE
▸ Training Set

▸ Test Set

▸ Algorithms

▸ SVM

▸ KNN
CRISPR
▸ What is it?

▸ Is a gene editing technology that cuts and alters DNA at


a specific section of a gene

▸ Applications

▸ Recently, it was used to identify HPV and Zika

▸ Can potentially be used to combat cancer, HIV, and ALS

▸ Can be used to edit diseases out of human embryos

▸ A problem scientists face is the effect an alteration on one


section will have on other genes.
HOW AI HELPS WITH CRISPR
▸ In the past, scientists would have had to run experiments
testing all possible cuts.

▸ This is costly and time-consuming.

▸ Instead, with AI and machine learning, they can run an


algorithm on CRISPR data to find a computational model

▸ This tells them which sites CRISPR would have the


most beneficial effect on.
LINKS

▸ https://blogs.microsoft.com/ai/crispr-gene-editing/

▸ https://cspo.org/where-genome-editing-and-artificial-
intelligence-collide/

▸ https://singularityhub.com/2018/02/15/the-power-to-
upgrade-our-biology-and-the-ethics-of-human-
enhancement/#sm.0019a6tdjg04e3311491wmvfjcnkg

▸ https://www.engadget.com/2018/02/15/crispr-detect-
hpv-and-zika/

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