DOWICIL 200 Preservative

Reliable, broad-spectrum antimicrobial protection

for cosmetics and personal care formulations
DOWICIL 200 Preservative offers an ideal
combination of properties for preserving
most cosmetic and personal care products
More and more, formulation chemists, Well-documented, favorable Cost effective
microbiologists and toxicologists are speci- toxicologic profile
When you formulate with DOWICIL 200,
fying DOWICIL* 200 Preservative for Extensive toxicologic studies conducted on you’re working with one of the most cost-
antimicrobial protection in cosmetic and DOWICIL 200 Preservative both at Dow effective preservatives available. Because
personal care formulations. There is no laboratories and in independent institutions it’s highly effective at low concentrations,
single reason why. Rather, it’s because show a quite favorable toxicologic profile DOWICIL 200 shouldn’t represent more
DOWICIL 200 offers a unique combination for this product. Well-documented skin, eye than a small fraction of your total formula-
of desirable properties. Here’s an initial and ingestion studies have been conducted tion costs.
look at some of those properties, and how in animals, and additional irritation and sen-
they may prove beneficial in your new or sitization studies have been conducted in Easy to work with
existing formulation. humans. The results indicate that DOWICIL DOWICIL 200 is remarkably easy to incor-
Effective at low concentrations 200 should not present any hazards through porate into your formulation. You get the
its proper handling during manufacturing or flexibility to work with a highly uniform,
DOWICIL 200 Preservative is highly effec- use by the consumer in finished products. free-flowing powder that disperses and dis-
tive at low concentrations. Typically, 0.02 to Further information is available through solves readily into the water phase of your
0.2% by weight of DOWICIL 200 provides your Dow representative. formulation. You can also premix DOWICIL
dependable antimicrobial activity in most
200 into an aqueous concentrate just before
formulations. High water solubility, virtually
adding it to your formulation. Either way,
insoluble in oil
Broad spectrum effectiveness you get the same reliable antimicrobial
DOWICIL 200 is highly soluble in water, effectiveness.
When you formulate with DOWICIL 200, while remaining virtually insoluble in oils
you’re working with a material that’s proven The following pages will give you a closer
or organic solvents. As a result, it stays in
effective against a broad variety of bacteria, look at some of the properties of DOWICIL
the aqueous component of your formulation,
yeasts and molds. 200 Preservative discussed here only briefly.
where microorganisms can live. That can
mean less preservative is needed to protect You’ll discover some of the reasons for its
Excellent formulation compatibility
the total formulation and that means lower broad compatibility, and learn about Dow
The many formulations that include costs. services that can provide considerable
DOWICIL 200 are the best testament to its assistance as you develop your formulation.
compatibility with an enormous variety of Shelf life in formulations There’s also more detailed technical infor-
ingredients and total formulation systems. At the dilute levels (typically 0.02 to 0.2%) mation about DOWICIL 200, including
The antimicrobial activity of DOWICIL 200 used in finished formulations, DOWICIL toxicologic properties, formulating consid-
is independent of system pH between 4 and 200 Preservative remains highly effective erations, and proper handling methods.
10, and it displays excellent compatibility for two or more years.
with proteinaceous matter. Moreover,
DOWICIL 200 is not inactivated by nonionic,
anionic or cationic formulation ingredients.

*Trademark of The Dow Chemical Company 1

 DOWICIL 200 Preservative is compatible
with a broad array of cosmetic and
personal care formulations
Given the almost unlimited number of poten- Good with protein, surfactants,
tial combinations of ingredients for cosmetic and parabens
and personal care products, it’s impossible to Finally, DOWICIL 200 Preservative displays
guarantee that any one preservative will be excellent compatibility with many common
compatible with all formulations. formulation ingredients. For example, its
On the other hand, the sheer weight of variety effectiveness is not diminished by relatively
and numbers of formulations currently using high concentrations of proteinaceous matter or
DOWICIL 200 makes a convincing case for sulfite-containing products. DOWICIL 200
its broad compatibility with ingredient materi- retains its antimicrobial activity in the pres-
als and formulation systems. ence of anionic, nonionic and cationic formu-
lation ingredients. Moreover, DOWICIL 200
Now in thousands of formulations displays excellent compatibility with
DOWICIL 200 Preservative is currently pro- parabens.
viding safe, effective antimicrobial perfor- There are many good reasons to give DOWICIL
mance in thousands of formulations. And 200 first consideration as you evaluate the
those formulations are a cross-section of compatibility of various preservative systems
almost all types of cosmetic and personal with your formulation.
care products.
But the question still remains: “Is DOWICIL
There are a number of identifiable reasons for 200 compatible with my formulations?” Only
the popularity of DOWICIL 200. actual formulation testing can give a definitive
Low concentration answer. But the following list of product types
that are successfully using DOWICIL 200
One reason is that DOWICIL 200 is effective helps to illustrate its tremendous versatility.
at low concentrations – typically 0.02 to 0.2%
by weight in formulations.

Active from pH 4 through 10

The antimicrobial activity of DOWICIL 200
is essentially uniform between pH 4 and pH
10. So DOWICIL 200 can be considered com-
patible with almost any formulation from a
pH standpoint. Moreover, the wide pH “win-
dow” offered by this preservative provides a
margin of assurance in the event of moderate
pH drift by the formulation.

2
Hair care products Shaving products
conditioners protein shampoo shaving creams shaving gels
protein conditioners aloe shampoo shaving lotions
herbal shampoo finishing rinses
conditioning shampoo hair creams Suntanning products
medicated shampoo hair rinses
suntan lotion suntan oil
setting lotion texture lotion
tanning accelerators sunscreens
styling lotion

Raw materials
Eye area products
proteins shampoo base
mascara eyeliner
surfactants
eye shadow creamy powder
eye color
Ethnic market products
Lotions hair moisturizers styling mousses
hair dressings curl activators
moisturizing lotion cocoa butter lotion
hair conditioners makeups
body and skin lotions cleansing lotion
hair straighteners

Baby products
Miscellaneous
baby shampoo baby lotion
beauty masks bath preparations
baby powder baby oil
makeup base corn silk
waterless hand cleaners liquid hand soaps
Powders scrub masks liquid makeup
blush dusting powders
pressed powders talcum powders
bath powder

Creams
skin cream night cream
moisturizing cream aloe cream
foot and hand cream cold cream

3
 Physical Properties of
DOWICIL 200 Preservative
(Laboratory results typical of the products; not to be considered specifications.)

DOWICIL 200 Preservative is a highly effec- The fine powder form of DOWICIL 200
tive antimicrobial that has proven its effective- Preservative is hygroscopic. Therefore, ship-
ness in numerous formulations in virtually ping/storage containers must be kept closed
every major cosmetic and personal care (when not in use) to prevent caking and
product category. discoloration.
Figure 1 – Molecular Structure of DOWICIL NOTE: Caking and discoloration do not
200 Preservative impair antimicrobial properties, but may
adversely affect the aesthetic appearance
of end products.

Solubility
The solubility characteristics of DOWICIL
200 in common cosmetic ingredients are seen
in Table 1. This table shows that DOWICIL
200 is highly soluble in water and has very
low solubility in non-aqueous solvents. Little
Formula . . . . . . . .C6H12N4(CH2CHCHCl)Cl or no DOWICIL 200 Preservative migrates to
CTFA Label Name . . . . . . . . .Quaternium-15 the oil phase of a cosmetic product. Instead, it
Molecular Weight . . . . . . . . . . . . . . . . .251.2 stays in the water phase, where it can be most
Bulk Density lb/ft 3 . . . . . . . . . . . . . . . . .25.0 effective against microorganisms.
CAS#: 51229-78-8
Table 1 – Solubility of DOWICIL 200 in
Sales Specifications Common Cosmetic Ingredients
In Grams/100
(Method of Analysis 24710a) Grams of
Description . . . . . . . . . . .Off-white powder Solvent Solvent @ 25°C

Active ingredient† . . . . . . .94% (minimum) Water . . . . . . . . . . . . . . . . . . . . . . . . . 127.2

Color, Gardner Methanol (anhydrous) . . . . . . . . . . . . . . 20.8
(2% aqueous solution) . . . . . .2 (maximum) Propylene glycol, USP . . . . . . . . . . . . . . 18.7
Sieve analysis: Glycerine (99.5%) . . . . . . . . . . . . . . . . . 12.6
Through No. 20 Ethanol (absolute) . . . . . . . . . . . . . . . . . . 2.04
(U.S. Standard Sieve) . . . . . . . . . . . .100% Isopropanol (anhydrous) . . . . . . . . . . . . <0.1
Mineral Oil . . . . . . . . . . . . . . . . . . . . . . <0.1
†
Cis isomer 1-(3-chloroallyl)-3,5,7-triaza-1-azonia-
adamantane chloride

4
Solution pH
Fresh aqueous solutions of DOWICIL 200
have a pH of 4.5 to 5.5. After standing for
several hours, these solutions will drift slight-
ly and attain an equilibrium pH of 6.5 to 7.5.

Broad spectrum antimicrobial effectiveness Table 2 – Antimicrobial and Antifungal

Efficacy of DOWICIL 200 —
The function of a preservative is to prevent the Agar1 Inhibition Data
growth of microorganisms. As the data in Table Concentration (ppm) of
2 show, DOWICIL 200 Preservative is highly DOWICIL 200 Required
Test Organism to Inhibit Growth
effective against both bacteria and fungi.
Bacteria
The agar inhibition data in Table 2 are just a
Bacillus subtilis, ATCC 8473 . . . . . . . . . . . . .60
starting point. We’ve also run laboratory eval-
uations on many different types of cosmetic Burkholderia cepacia, ATCC 25416 . . . . . . .60

formulations. These tests consistently demon- Citrobacter freundii, ATCC 43864 . . . . . . . .60
strate that concentrations of DOWICIL 200 Enterobacter aerogenes, ATCC 13048 . . . . .80
Preservative from 0.02 to 0.2% by weight Enterobacter gergoviae, ATCC 33028 . . . .240
maintain effective control after repeated insult. Escherichia coli, ATCC11229 . . . . . . . . . . .100

Obviously, the most effective level of Pseudomonas aeruginosa, ATCC 19429 . . .320
DOWICIL 200 should be determined for each Pseudomonas aeruginosa, ATCC 10145 . . .240
formulation using appropriate testing proce- Pseudomonas aeruginosa PRD10,
dures. That’s the only way to precisely ATCC 15442 . . . . . . . . . . . . . . . . . .160
determine the antimicrobial activity of any Pseudomonas oleovarans, ATCC 8062 . . . .160
preservative in a given formulation. Dow Staphylococcus aureus, ATCC 6538 . . . . . . .60
offers a 10-Cycle Challenge Test to assist in Fungi
determining the effective level of preservative Aspergillus niger, ATCC 16404 . . . . . . . . . .500
required for a formulation. Candida albicans, ATCC 10231 . . . . . . . . . .250
1
Bacterial tests were run with nutrient agar (Difco
Laboratories); Fungal tests were run on malt agar (Difco) with
added yeast extract.

5
 How the Dow 10-Cycle
Challenge Test is performed

How the Dow 10-Cycle Challenge Test Advantages of the 10-Cycle Test procedure
is performed The 10-Cycle Test method provides you with
One effective test method is the 10-Cycle two fundamental benefits.
inoculation-incubation procedure. We’ll be First, it’s a repeated inoculation study involv-
glad to run the procedure on your formulation ing a large number of insults. So it’s a good
to help you evaluate DOWICIL 200. The fol- simulation of the type of repeated exposure
lowing summary will familiarize you with the your formulation may be subjected to during
test method. manufacturing, shipping and consumer use.
1) Samples are tested for sterility. Second, the Dow test is designed to reveal
2) Each sample is inoculated with a 24-hour the level of preservative required to protect
culture of mixed bacteria, followed by an a specific formulation. That eliminates much
incubation period lasting 24 hours. The of the guesswork from cost analysis and
samples are then streaked on nutrient agar. compatibility studies.
Both the samples and the agar plates are
incubated for 48 hours, after which the
plates are read for growth.
3) Allowing 24 hours between test cycles,
step 2 is repeated for a total of ten
inoculation-incubation cycles. The preser-
vative is considered to provide adequate
in-use antimicrobial activity only if no
microbial contamination occurs during
the ten test cycles.
This basic test procedure can also be per-
formed with additional samples, using yeast
or mold for inoculation, with appropriate
changes in culture media, number of inocula-
tions, temperature, and incubation time.

6
Put unique Dow services and expertise
to work in your formulation

Free formulation testing and additional So if you have a question about the proper-
lab services ties of a basic formulation ingredient, it’s
Challenge testing of your formulation is a more than likely Dow can help.
primary service offered free of charge by
Dow makes antimicrobials for more than
The Dow Chemical Company. We’ll be glad
just cosmetics
to test the effectiveness of DOWICIL 200
in your formulation with our 10-Cycle Our ability to provide formulators with
Challenge Test. technical assistance is also based on a com-
prehensive understanding of antimicrobials
We’ll test your formulation with the levels of
well beyond cosmetics.
preservative you select. The results you’ll get
will tell you whether the levels you’ve cho- Dow also manufactures antimicrobials for
sen will adequately protect your formulation. adhesives, paints, metalworking fluids, pulp
and paper products, latex, waxes, cooling
towers, disinfectants, cleaners, pet care
products, and textiles, to name a few. You
might be surprised to learn how many basic
ingredients these water-based products have
in common with cosmetics.
The information you obtain from Dow testing In addition, we produce low-persistence
can be quite valuable, regardless of the size or biocides for use in enhanced oil recovery
sophistication of your operation. Our tests systems and many types of circulating
provide useful data that can dovetail with the water systems.
results of separate tests. Getting started is as
Those applications probably don’t relate
easy as picking up your phone and contact-
directly to your specific situation, but
ing your nearby Dow representative.
they do speak for a pool of experience and
Dow knows cosmetic ingredients diversity that’s unique among suppliers
of cosmetic preservatives.
When you work with Dow, you’ll also enjoy
the benefits of working with a major suppli-
er of many other cosmetic and personal care
product ingredients.
Ingredient materials produced by Dow
include solvents, stabilizers, texturizing
agents, aromatics, bases for creams and
pastes, humectants, emollients, neutralizers,
oxidizers, and thickening agents.

7
 Formulating with
DOWICIL 200 Preservative

Here are some general guidelines for adding

DOWICIL 200 Preservative to your formula-
tions. Contact your Dow representative for
assistance with specific formulations.

Preparing a Solution
A concentrated aqueous solution of DOWICIL
200 can be prepared by slowly adding the
appropriate amount of powdered preservative In any case, to obtain the maximum benefit
to water in a 1:1 or 1:2 ratio, at a temperature of DOWICIL 200, the preservative should be
below 45°C, and agitating until completely added after any processing steps requiring
dissolved. prolonged elevated temperature (>50°C).
Adding DOWICIL 200 to Aqueous Adding DOWICIL 200 to Anhydrous
Formulations Formulations
The cosmetics formulator enjoys flexibility DOWICIL 200 is an ideal preservative for use
when adding DOWICIL 200 to products. Dow in anhydrous formulations, as well. Its excep-
laboratory studies have shown that DOWICIL tionally high water solubility gives DOWICIL
200 can be incorporated into formulations by 200 the ability to eliminate the microbial
different methods – all resulting in equal contamination that may be present if small
preservative effectiveness. amounts of moisture are introduced into the
• DOWICIL 200 may be added either as a product during use. Products such as mascaras,
free-flowing powder or as a water concen- eye shadows, eyeliners, and pressed powders,
trate to the final product. It’s preferable to for example, can be effectively preserved
add DOWICIL 200 during the cooling against repeated user contamination by grind-
phase, when formulation temperatures are ing DOWICIL 200 into the color powder mix.
below 50°C. If you must add the preserva- Although DOWICIL 200 has been incorporat-
tive to formulations at temperatures above ed into anhydrous formulations at tempera-
50°C, consult your Dow representative for tures exceeding 80°C without exhibiting loss
assistance. of antimicrobial activity, formulators are urged
• It is often more convenient to add the to limit any exposure to elevated temperatures,
antimicrobial to the water phase immediately and to consult with a Dow representative if
before mixing it with the oil phase during desired.
the formulating process.

8
pH Discoloration
Fresh aqueous solutions of DOWICIL 200 Some formulations containing DOWICIL 200
have a pH of 4.5 to 5.5. Solution pH will will demonstrate a slight to pronounced yel-
subsequently drift. After several hours, an low discoloration. This occasional problem
equilibrium pH of 6.5 to 7.5 will be obtained. has been linked to a combination of DOWICIL
These solutions, or products containing 200 and fragrances that incorporate citral.
DOWICIL 200, can be pH-adjusted with organ- Interestingly, the yellowing phenomenon
ic acids or bases. A variety of buffer systems apparently occurs in only a few systems
may also be used. Avoid the use of strong acids containing this combination.
or bases (e.g., concentrated HCl or NaOH), The advantages of using DOWICIL 200 need
since DOWICIL 200 generally becomes unsta- not necessarily be ruled out if yellowing
ble below a pH of 4 and above a pH of 10. occurs. In the event of incompatibility, the
Some formulations and/or ingredients may be presence of citral in the fragrance should be
sensitive to changes in pH. The potential for evaluated. It is important for formulators to be
undesirable effects can be minimized by aware of the phenomenon and to make appro-
preparing stock solutions containing priate tests for compatibility.
DOWICIL 200 and allowing them to equili- In addition, corrective measures may often
brate prior to use. solve compatibility problems even if citral
is present.
Table 3 – Suggested Starting-Point
Concentrations of DOWICIL 200 In many instances, small quantities of sodium
Preservative in Selected Products borate or sodium sulfite have been effective in
Types1 preventing this discoloration. However, avoid
Product Type% by Weight of DOWICIL 200 using strong oxidizing or reducing agents,
Creams and lotions .05-.20 since these additives may adversely affect the
Shampoos .05-.30 antimicrobial performance of DOWICIL 200.
Pressed powders .05-.10 The propensity for DOWICIL 200 to discolor
Mascara .05-.20 in any particular formulation can be deter-
Suncare products .05-.15 mined simply by storing the formulation at 45
Shaving products .05-.15 to 50°C for 48 hours. Discoloration should
Raw materials .05-.30 not be a factor if none occurs during that time.
1
Preservative concentration ranges are based on data avail-
able at time of publication, and are presented as suggested
starting points only. The most effective level of DOWICIL
200 in specific formulations should be determined through
the use of appropriate test procedures.

9
 Shelf Life of Concentrated Solutions Packaging Considerations for Products
The antimicrobial activity of concentrated Containing DOWICIL 200
solutions of DOWICIL 200 gradually No incompatibility problems are known to
diminishes over time. For optimal preserva- exist between DOWICIL 200 and commonly
tive performance, do no store stock solu- used packaging materials. However, to
tions longer than two weeks. ensure that products formulated with
DOWICIL 200 maintain maximum antimi-
Shelf life in formulations crobial activity during subsequent storage
At the dilute levels (typically 0.02 to 0.2%) and use, packaging material should be treated
used in finished formulations, DOWICIL as a formulation ingredient for the purposes
200 Preservative remains highly effective of compatibility testing.
for two or more years.
Lab samples of DOWICIL 200
Using DOWICIL 200 in Combination DOWICIL 200 Preservative is hygroscopic,
with Other Antimicrobials and the small lab samples supplied to for-
Challenge test results show that cost- mulators may, as a result, begin to discolor
effective concentrations of DOWICIL 200 and become caked after a few months. To
provide excellent antimicrobial activity avoid this, we suggest replacing lab samples
against even the most stubborn organisms. of DOWICIL 200 every six months. Please
Combinations with methyl, propyl, and/or contact your Dow representative to order
ethyl paraben at levels of 0.2 to 0.3% total replacement samples.
parabens are sometimes used. Incorporation
of EDTA at 0.05 to 0.1% may be useful in
some cases as well.
The free formulation challenge testing ser-
vice available from Dow can help you
determine the most cost-effective level of
DOWICIL 200 Preservative for achieving
broad-spectrum antimicrobial performance
in your specific system.

10
Comprehensive Testing
Shows a Favorable
Toxicologic Profile
Extensive animal as well as human studies
have provided a comprehensive base of
safety substantiation data on DOWICIL 200
Preservative. The results of these studies
point to the conclusion that DOWICIL 200 Skin use concentrations up to 0.75%. It was con-
has a favorable toxicologic profile. The cluded that DOWICIL 200 Preservative is
material should present no serious handling, As a dry powder or in solution (10%),
DOWICIL 200 Preservative is, at most, not a primary irritant, fatiguing agent, skin
utilization or waste disposal problems when sensitizer or photosensitizer at concentra-
handled in accordance with the material slightly irritating to the skin. Stronger solu-
tions and the powdered concentrate, moist tions up to 1%. Higher concentrations may
safety data sheet and label instructions. be weak skin sensitizers in susceptible
and confined to the skin, can cause moder-
This section provides summary toxicologic ate skin irritation and possibly a burn. individuals.
information obtained from on-going Dow NOTE: The toxicologic characteristics of
studies. Further information is available As a dry powder, DOWICIL 200 is not
absorbed through the skin in acutely toxic DOWICIL 200 Preservative are a prime
through your local Dow representative. focus of continuing Dow studies. Information
amounts. The material may be absorbed
Eye through the skin in harmful amounts if in in addition to the summaries in this bulletin
strong solution or if the skin is irritated or is available from your Dow representative.
DOWICIL 200 Preservative, undiluted, is
no more than slightly irritating to the eye. abraded. These data substantiate the relative safety
Direct contact with the eye may result in A study in pregnant rats showed no mater- of DOWICIL 200 in cosmetics and person-
some discomfort and slight transient con- nal or fetal toxicity nor any birth defects al care products. However, we do not have
junctival irritation, which would be expected resulting from dermal application of knowledge of, or control over, customers’
to subside promptly. DOWICIL 200 in a 50% aqueous solution formulations or end products. Responsi-
at dose levels of 250 or 500 mg/kg/day. bility for adequate testing to establish
Ingestion safety of final products must be assumed
The single dose oral toxicity of DOWICIL Human skin studies by the cosmetics formulator.
200 is low in all animal species tested, with DOWICIL 200 was tested in human studies Discuss your needs and interests for further
the exception of rabbits. LD50 values were for skin irritation, skin fatiguing, sensitiza- information with your Dow representative. Be
found to be as follows: male and female tion and photosensitization properties. These certain to request the most current MSD sheet
rats, 940-2664 mg/kg; mice,1310 mg/kg; tests were conducted with aqueous solutions prior to handling or using DOWICIL 200.
male guinea pigs, 710 mg/kg; male chicks, of the preservative and with freshly made
2800 mg/kg; female rabbits, 78 mg/kg. and aged prototype cosmetic formulations at

11
 Safe use and handling of
DOWICIL 200 Preservative

These precautions are general in nature and Ventilation to control dusts below an expo- Thermal decomposition
are directed toward exposure to undiluted sure guideline of 1 mg/m3 is recommended.
DOWICIL 200 Preservative is an organic
DOWICIL 200 Preservative or strong solu- If necessary, provide personnel with dust
material that can undergo exothermic
tions (10% or more). Specific recommen- respirators and enforce their use. All person-
decomposition when the dry powder is
dations can be made only when specific nel working with the product should wear
exposed to elevated temperatures (>100°C).
handling conditions are known. clean, body-covering clothing. Use adequate
eye protection, such as safety glasses. Decomposition will take place with evolu-
Handling Locate any eye wash station reasonably tion of toxic, flammable vapors. If such
Observe reasonable precautions to avoid close to personnel working with the product. decomposition occurs in a closed container,
ingestion and skin contact, especially with violent rupture of the container is possible.
strong (10% or more) aqueous solutions. Storage
Make fire fighters aware of possible hazards.
Avoid contact with the undiluted material Keep DOWICIL 200 Preservative in closed They should use self-contained breathing
when the skin is wet, as with perspiration. containers, in a dry, cool area. To avoid apparatus if exposure to vapors is possible.
Keep concentrated solutions or the dry decomposition, which will release smoke Extinguish fires involving DOWICIL 200
powder of DOWICIL 200 away from cuts and flammable vapors, store below 120°F with water fog.
or wounds. (49°C). Keep away from heat, sparks and
open flame. Do not store DOWICIL 200 Customer Notice
After working with DOWICIL 200, wash
the hands and face well before eating or near flammable materials. Dow encourages its customers to inde-
smoking. Remove grossly contaminated pendently review their applications of
Disposal
clothing as soon as possible and wash it Dow products from the standpoint of
before reuse. Wash contaminated skin with Spills can be swept up. Use a floor sweep- human health and environmental quality.
soap and a large quantity of water. Person- ing compound, then flush the spill area with It is important that each customer ensure
nel working in a dusty atmosphere should water to ground. Avoid contamination of that Dow products are not used in ways
shower and change clothing at the end of public water supplies. Collected (swept-up) for which they are not intended or tested.
each work period. material can be disposed of either by burial For specific information, refer to the cur-
or incineration in accordance with local rent material safety data sheet for
regulations. DOWICIL 200.
In disposal of any wastes, be certain all
applicable federal, state and local regula-
tions are met.

12
 For more information about DOWICIL 200 Preservative:
From the U.S. and Canada call 1-800-447-4369
From Mexico call 95-880-447-4369
In Europe call +31/20.691.6268
fax +31/20.691.6418
In Asia call +852/2879.8222
fax +852/2827.7860

NOTICE: No freedom from any patent owned by Seller or others is to be inferred. Because use conditions and applicable laws may differ from one location to anoth-
er and may change with time, Customer is responsible for determining whether products and the information in this document are appropriate for Customer’s use and
for ensuring that Customer’s workplace and disposal practices are in compliance with applicable laws and other governmental enactments. Seller assumes no obliga-
tion or liability for the information in this document. NO WARRANTIES ARE GIVEN; ALL IMPLIED WARRANTIES OF MERCHANTABILITY OR FITNESS
FOR A PARTICULAR PURPOSE ARE EXPRESSLY EXCLUDED.

Printed in U.S.A.
Published May 1999 *Trademark of The Dow Chemical Company Form No. 253-01176-5/99GW