Titan3 and Target2

2
Syringe filter membrane
selection Compatibility of membrane with
The following is a general guide when selecting the appropriate
solvent
membrane for your application. The following should be
considered: Water /Soluble Organic

1
• CA • PTFE
• Nylon • PTFE-L
Membrane compatibility with • PES • PVDF
sample type and technique • PTFE-L • RC

3
• Aggressive and nonpolar solvents PTFE
• Organic/Aqueous Solvents PTFE-L
Filter size is dependent on sample
• Biological sample preparation RC
volume
• Capillary electrophoresis PES
• High solid samples GMF/pre-filter • <2 mL 4 mm
• HPLC PVDF/Nylon/RC/ • <10 mL 17 mm
PTFE-L • <100 mL 30 mm
• Ion-chromatography PES/PVDF

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• Protein analysis PVDF
• Trace metals PES Porosity depends on the amount
• UV-Vis spectophotometry PVDF of particles to be removed from
the sample

• >5 µm GF pre-filter
For more detailed information on individual • <2 µm 0.45 µm
membrane specifications, please see pages 5 - 9.
• <0.5 µm 0.2 µm

Titan3 Syringe filter unit specification Target2 Syringe filter unit specification

4 mm Titan3 17 mm Titan3 30 mm Titan3 4 mm Target2 17 mm Target2 30 mm Target2

Polypropylene with Polypropylene with Polypropylene with

Housing integral colour-coded integral colour-coded integral colour-coded Housing Polypropylene Polypropylene Polypropylene
sealing ring sealing ring sealing ring
Filtration area 0.125 cm2 1.6 cm2 4.9 cm2 Filtration area 0.125 cm2 1.6 cm2 4.9 cm2
Maximum pressure 5.5 BAR 8 BAR 10 BAR Maximum 5.5 BAR 8 BAR 10 BAR
pressure
Residual volume <15 µL with air purge <35 µL with air purge <157 µL with air purge Residual volume <15 µL with air purge <35 µL with air purge <157 µL with air purge
Dimensions 8 mm × 20.7 mm 20.5 mm × 24.5 mm 34 mm × 24.5 mm Dimensions 8 mm × 20.7 mm 20.5 mm × 24.5 mm 34 mm × 24.5 mm
Flow direction Inlet-outlet only Inlet-outlet only Inlet-outlet only Flow direction Inlet-outlet only Inlet-outlet only Inlet-outlet only
Inlet Female luer lock tab Female luer screw Female luer screw Inlet Female luer lock tab Female luer screw Female luer screw
Outlet Male luer slip Male luer slip Male luer slip Outlet Male luer slip Male luer slip Male luer slip
Pre-filter N Selected membranes Selected membranes Pre-filter N N Selected membranes

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 Titan3 and Target2

Syringe filter membrane

specification

PVDF syringe filters

Superior membrane quality for HPLC.
• Low non-specific binding with exceptional chemical resistance
• Hydrophilic membrane provides excellent flow rates and low
binding coefficients
• Certified for chromatographic performance
• Compatible with a wide range of aqueous and organic-based
sample environments
• Recommended for HPLC and UHPLC

PVDF syringe filters have a well­ defined pore structure, giving

effective retention of particles without excessive pore blockage.
Compatible with aqueous and most organic solvents. They are
excellent general filters for HPLC and organic solvent sample
clean up.

Specifications
Membrane: HPLC certified PVDF
Max. operating 100°C
temperature:
Housing: medical grade, virgin polypropylene
Pre-filter: binder free glass microfiber 1 µm
(0.20 µm only)
Porosities: 0.20 µm, 0.45 µm
Autoclave: Sterilize by dry heat at 121°C for 15 minutes

Applications
• HPLC and organic solvent sample preparation and clean up
• Protein based samples with high non-specific binding
• Environmental water samples

Chemical Incompatibilities
• DMF, DMSO, MEK, acetone and most caustic solutions >6N

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 Titan3 and Target2

Nylon syringe filters PES syringe filters - Ion

chromatography (IC) certified
Membrane of choice for analytical applications. Precise results in sensitive analysis of ionic analytes.
• Naturally hydrophilic with broad chemical resistance • Certified for low-level IC interference by ICP analysis
• Excellent flow rates and high-throughput loading • Hydrophilic membrane provides excellent flow rates and low
• HPLC recommended binding coefficients
• Low affinity for binding drugs, ideal for dissolution testing
procedures
Hydrophillic nylon is extremely well suited for aqueous or organic
sample preparation and HPLC, GC or dissolution sample analysis.
Due to its excellent flow characteristics and mechanical stability, This hydrophilic polymer has excellent cleanliness and is
nylon offers the best combination of physical parameters to meet compatible with a wide range of solvents. It is the membrane of
the most stringent analytical needs. choice for ion chromatography applications.

Specifications Specifications
Membrane: HPLC certified nylon Membrane: ICP Certified PES (PolyEtherSulfone)
Max. operating 100°C Max. operating 100°C
temperature: temperature:
Housing: medical grade, virgin polypropylene Housing: medical grade, virgin polypropylene
Porosities: 0.20 µm, 0.45 µm, 1.5 µm, 5 µm Pre-filter: binder-free glass microfiber pre-filter
Autoclave: sterilize by dry heat at 121°C for 15 minutes (0.20 µm only)
Porosities: 0.20 µm, 0.45 µm

Applications Autoclave: Sterilize by dry heat at 121°C for 15 minutes

• HPLC and organic solvent sample preparation and clean up

• Dissolution sample analysis Applications

• General sample preparation prior to analytical analysis • IC sample preparation and analysis

• Mixed sample matrix of aqueous or organic dissolved analytes • Dissolution testing

Chemical Incompatibilities Chemical Incompatibilities

• Acids >1N • Protein-based samples in aqueous solutions

Halogenated solvents • Concentrated acids, chloromethane, chloroform, hexane,

acetone, MEK, THF, DMSO
• Proteineous samples with high non-specific binding affinities

Analysis results (ppb)

Method detection
Analyte 0.2µm PES 0.45µm PES
level (ppb)
Bromide < 100 < MDL < MDL
Chloride 20 < MDL < MDL
Fluoride 20 < MDL < MDL
Nitrate as N 50 < MDL < MDL
Orthophosphate as P < 100 < MDL < MDL
Sulfate < 100 < MDL < MDL
Barium 2 < MDL < MDL
Calcium 10 39.9 58.9
Potassium 50 80 70
Magnesium 20 < MDL < MDL
Sodium 20 80.6 63

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Titan3 and Target2

Cross reference Thermo Scientific

Titan3 Ring color
Thermo Scientific
Target2
syringe filter units Product code Product code
4 mm syringe filter 0.45 µm nylon 44504-NN Transparent Green F2504-1
4 mm syringe filter 0.2 µm polypropylene N/A F2504-10
4 mm syringe filter 0.45 µm cellulose acetate N/A F2504-15
4 mm syringe filter 0.2 µm cellulose acetate 44502-CA Light Green F2504-16
4 mm syringe filter 0.2 µm nylon 42204-NN Opaque Medium Yellow F2504-2
4 mm syringe filter 0.45 µm PTFE 44504-NP Transparent Yellow F2504-3
4 mm syringe filter 0.2 µm PTFE 42204-NP Transparent Blue F2504-4
4 mm syringe filter 0.45 µm PVDF 44504-PV Red F2504-5
4 mm syringe filter 0.2 µm PVDF 42204-PV Black F2504-6
4 mm syringe filter 0.45 µm regenerated cellulose 54504-RC Light Brown F2504-7
4 mm syringe filter 0.2 µm regenerated cellulose 52204-RC Granite F2504-8
4 mm syringe filter 0.45 µm polypropylene N/A F2504-9

17 mm syringe filter 0.45 µm nylon 44513-NN Transparent Green F2513-1

17 mm syringe filter 0.2 µm polypropylene 42213-PP Royal Blue F2513-10
17 mm syringe filter 0.45 µm PES for Ion chromatography 44513-PS Orange/Yellow F2513-14
17 mm syringe filter 0.45 µm cellulose acetate 44513-CA Transparent Orange F2513-15
17 mm syringe filter 0.2 µm cellulose acetate 42213-CA Light Green F2513-16
17 mm syringe filter 0.2 µm PES for Ion chromatography 42213-PS Dark Gray F2513-17
17 mm syringe filter 0.2 µm nylon 42213-NN Light Purple F2513-2
17 mm syringe filter 0.45 µm PTFE 44513-NP Transparent Yellow F2513-3
17 mm syringe filter 0.2 µm PTFE 42213-NP Transparent Blue F2513-4
17 mm syringe filter 0.45 μm hydrophilic PTFE 44513-NPL Purple
17 mm syringe filter 0.2 μm hydrophilic PTFE 42213-NPL Green
17 mm syringe filter 0.45 µm PVDF 44513-PV Red F2513-5
17 mm syringe filter 0.2 µm PVDF 42213-PV Black F2513-6
17 mm syringe filter 0.45 µm regenerated cellulose 54513-RC Light Brown F2513-7
17 mm syringe filter 0.2 µm regenerated cellulose 52213-RC Granite F2513-8
17 mm syringe filter 0.45 µm polypropylene 44513-PP White F2513-9

30 mm syringe filter 0.45 µm nylon with pre-filter 44525-NN Transparent Green F2500-1
30 mm syringe filter 0.2 µm polypropylene 42225-PP Royal Blue F2500-10
30 mm syringe filter 5.0 µm PTFE N/A F2500-11
30 mm syringe filter 1.25 µm nylon 41225-NN Opaque Medium Yellow F2500-12
30 mm syringe filter 1.0 µm PTFE 41025-NP Dark Blue F2500-13
30 mm syringe filter 0.45 µm PES for Ion chromatography 44525-PS Orange/Yellow F2500-14
30 mm syringe filter 0.45 µm cellulose acetate 44525-CA Transparent Orange F2500-15
30 mm syringe filter 0.2 µm cellulose acetate 42225-CA Light Green F2500-16
30 mm syringe filter 0.2 µm PES for Ion chromatography with pre-filter 42225-PS Dark Gray F2500-17
30 mm syringe filter 0.7 µm glass micro fiber 40725-GM Amber F2500-18
30 mm syringe filter 1.2 µm glass micro fiber 41225-GM Orange F2500-19
30 mm syringe filter 0.25 µm nylon 45025-NN Pink F2500-2
30 mm syringe filter 3.1 µm glass micro fiber 42725-GM Dark Purple F2500-20
30 mm syringe filter 0.45 µm PTFE with pre-filter 44525-NP Transparent Yellow F2500-3
30 mm syringe filter 0.2 µm PTFE with pre-filter 42225-NP Transparent Blue F2500-4
30 mm syringe filter 0.45 µm PVDF 44525-PV Red F2500-5
30 mm syringe filter 0.45 µm nylon 44526-NN White F2500-50
30 mm syringe filter 0.2 µm PVDF 42225-PV Black F2500-6
30 mm syringe filter 0.45 µm regenerated cellulose 54525-RC Light Brown F2500-7
30 mm syringe filter 0.2 µm regenerated cellulose 52225-RC Granite F2500-8
30 mm syringe filter 0.45 µm polypropylene 44525-PP White F2500-9
Alternative parts are based on a direct
30 mm syringe filter 0.45 µm nylon 44525-NN Transparent Green F2502-1
technical comparison.
30 mm syringe filter 0.2 µm nylon 42225-NN Light Purple F2502-2
Part number alternatives are based upon 30 mm syringe filter 0.20 µm polypropylene 42225-PP Royal Blue F2502-10
closest pack quantity. 30 mm syringe filter 0.45 µm PTFE 44525-NP Transparent Yellow F2502-3
Inclusion of parts is no guarantee of 30 mm syringe filter 0.45 μm hydrophilic PTFE 44525-NPL Purple
identical performance. 30 mm syringe filter 0.2 μm hydrophilic PTFE 42225-NPL Green
30 mm syringe filter 0.45 µm polypropylene 44525-PP White F2502-9
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