Manzana, Mary Eunice L.

PH3Y1-2 PHOS 313

ACTIIVITY NO. 4

Functions and responsibilities of Pharmacy and Therapeutics Committee

 The P&T committee is responsible for managing the formulary system. It is composed of actively
practicing physicians, other prescribers, pharmacists, nurses, administrators, qualityimprovement
managers, and other health care professionals and staff who participate in the medication-use
process. Customarily, P&T committee member appointments are based on guidance from the
medical staff.
 The P&T committee should serve in an evaluative, educational, and advisory capacity to the
medical staff and organizational administration in all matters pertaining to the use of medications
(including investigational medications).
 The P&T committee should be responsible for overseeing policies and procedures related to all
aspects of medication use within an institution.
 The P&T committee is responsible to the medical staff as a whole, and its recommendations are
subject to approval by the organized medical staff as well as the administrative approval process.
 The P&T committee’s organization and authority should be outlined in the organization’s
medical staff bylaws, medical staff rules and regulations, and other organizational policies as
appropriate.
Other responsibilities of the P&T committee include:
 Medication-use evaluation (MUE)
 Adverse-drug-event monitoring and reporting
 Medication-error prevention
 Development of clinical care plans and guidelines.

DRUG GENERIC
ROUTE OF 
BRAND NAME INDICATION
ADMINISTRATION
CLASSIFICATION NAME

1. Antacids, Antireflux 1. Omeprazole Na 1. Aeprazole 1. Conditions where inhibition of 1. Intravenous

Agents & Antiulcerants 2. Esomeprazole 2. Aesopra gastric acid secretion may be 2. Intravenous
Na 3. Dynastin beneficial including aspiration 3. Intravenous,
3. Ranitidine HCl 4. Pantoprin syndromes, dyspepsia, GERD, PUD Intramuscular
4. Pantoprazole 5. Omezol & Zollinger-Ellison syndrome 4. Oral
5. Omeprazole Na 2. GERD in patients with esophagitis & 5. Intravenous
sever symptoms of reflux; healing of
gastric ulcers associated with NSAID
therapy ;prevention of gastric and
duodenal ulcers associated with
NSAID therapy and rebleeding
following therapeutic endoscopy for
acute bleeding and gastric or
duodenal ulcers
3. Duodenal ulcer, active &benign
gastric ulcer, peptic ulcer, reflux
esophagitis, Zollinger-Ellison
syndrome
4. GERD, PUD; prophylaxis for
 NSAID-associated
ulceration;Zollinger-Ellison
syndrome
5. Condition where inhibition of gastric
acid secretion may be beneficial,
including aspiration syndrome,
dyspepsia, GERD, peptic ulcer and
Zollinger syndrome

1. Treatment of depression.
Management of bulimia nervosa &
obsessive compulsive disorder.
2. Treatment of depression; generalized,
social anxiety, obsessive-compulsive
&panic disorders.
1. Fluoxetine HCl
3. Treatment &prophylaxis of mania.
2. Escitalopram 1. Drafzin 1. Oral
Prophylaxis of manic
oxalate 2. Escinal 2. Oral
depression(bipolar disorders) &
2. Antidepressants 3. Lithium 3. Litcab 3. Oral
recurrent unipolar depression
carbonate 4. Prodin 4. Oral
4. Depression & associated conditions
4. Fluoxetine HCl 5. Sernade 5. Oral
of anxiety, bulimia nervosa,
5. Sentraline HCl
obsessive compulsive &premenstrual
dysphoric disorder.
5. Depression; obsessive compulsive,
panic, social anxiety, post traumatic
stress & premenstrual dysphoric
disorders.

1. Management of hypertension,
angina pectoris, cardiac arrhythmias
& MI, prophylactic treatment of
migraine.
2. Mangement of HTN & angina
pectoris. Adjunct to standard
1. Atenolol therapy in symptomatic heart
1. Cardioten 1. Oral
2. Carvedilol failure. Reduce mortality in patients
2. Carvenal 2. Oral
3. Nebivolol HCl with left ventricular dysfunction
3. Beta-blockers 3. Nebilet 3. Oral
4. Nifedipine after MI.
4. Adalat Gits 4. Oral
5. Amlodipine 3. Treatment of essential HTN &
5. Amlodac 5. Oral
besilate stable mild &moderate chronic
heart failure in addition to standard
therapies in elderly patients.
4. CHD eg, chronic stable angina
pectoris (angina of effort), HTN
5. Treatment of HTN & prophylaxis
angina.

4. Antidiarrheals 1. Loperamide HCl 1. Diatabs 1. Symptomatic control of acute 1. Oral

2. Racecadotril 2. Diatril &chronic diarrhea. Ileostomy. 2. Oral
3. Racecadotril 3. Racecore 2. Symptomatic treatment of acute 3. Oral
4. Loperamide HCl 4. Lopran diarrhea. 4. Oral
5. Bacillus clausii 5. Erceflora 3. Symptomatic treatment of acute 5. Oral
 diarrhea.
4. Management of acute &chronic
diarrhea.
5. Acute diarrhea ≤14 days
duration due to infections, drugs
or poisons. Chronic or persistent
diarrhea >14 days duration.

Reference/s: 

MIMS Philippines. (2017) Issue 3

QUESTIONS:

1) Describe the function of the Pharmacy and Therapeutics Committee in drug selection.

2) What is the difference between generic and brand names?

  Brand name or the trade name of a medication is given by the company or manufacturer that
produces the drug that is usually for sales and marketing purposes. Generic name, on the other hand, is
the name of the active ingredient in the medication.
3) List various dosage forms and routes of administration of drugs.
 Solid Dosage forms  Capsules
 Tablets/ Caplets ▫ Spansules
▫ Chewable Tablet ▫ Sprinkle Capsules
▫ Oral disintegrating tablet  Lozenges/ Troches/ Pastilles
▫ Enteric coated tablets  Powders and Granules
▫ Film Coated Tablets
▫ Sugar Coated Tablets Semisolid Dosage forms
  Ointments ▫ Spirit
 Creams ▫ Irrigating solution
 Lotions ▫ Parenteral solution
 Gels  Dispersions
 Pastes ▫ Suspension
 Suppositories ▫ Aqueous suspension
 Enemas
Liquid Dosage Forms
 Solutions Inhalation Dosage Forms
▫ Aromatic Water  Aerosols
▫ Elixir  Spray
▫ Syrup
▫ Extract Transdemal Dosage Forms
▫ Tincture  Transdermal patch

Routes of Administration of drugs

 Buccal  Itraperitoneal  Oral
 Dental  Intramuscular  Otic
 Epiural  Intraocular  Perfusion
 External  Intrapleural  Rectal
 Implant  Intrathecal  Subcutaneous
 In vitro  Intrauterine  Sublingual
 Inhalation  Intravenous  Transdermal
 Injection  Intravesical  Translingual
 Intra-arterial  Irrigation  Urethral
 Intra-articular  Mouth/throat  Vaginal
 Intracavernosal  Nasal
 Intradermal  Ophthalmic

4) Define the following terms:

a) analgesic – insensible to pain; alleviating pain; a drug which relieves pain
b) antiarrhythmic – counteracting or preventing cardiac arrhythmia
c) antibiotic – a substance produced by or a semi synthetic substance derived from a microorganism and
able in dilute solution to inhibit or kill another microorganism
d) anticholinergic – opposing or blocking the physiologic action of acetylcholine
e) antidiarrheal – tending to prevent or relieve diarrhea
f) antiemetic – used or tending to prevent or relieve nausea and vomiting
g) antihypertensive – any agent that reduces blood pressure
h) antineoplastic – inhibiting or preventing the growth and spread of tumors or malignant cells
i) antipyretic – any agent which allays or reduces fever
j) anti-inflammatory – substance that is used to control or reduce inflammation
k) antihistamine – a drug that is used to treat allergic reactions and colds; any various compounds that
counteract histamine in the body and that are used for treating allergic reactions and cold symptoms.
l) antihelmintic - medicines used to destroy parasitic worms.
m) carminative -– drug relieving flatulence
n) cathartic – providing psychological relief through the open expression of strong emotions; causing
catharsis.
o) counterirritant – an agent applied locally to produce superficial inflammation with the object of
reducing inflammation in deeper adjacent structures
p) diuretic – an agent which increases the flow of urine
q) expectorant – a drug which promotes or increases expectoration
r) hypoglycemic – decreased blood sugar, attended by anxiety, excitement, perspiration, delirium or coma
s) laxative - drug or medicine tending to stimulate or facilitate evacuation of the bowels.
t) mucolytic – drugs which soften mucus and so reduce viscosity of secretion from respiratory tract
 

Reference/s: 

Shah, B. M., Gibson, J. L., & Tex, N. L. (2013). The 21st century pharmacy technician. Burlington, MA:
Jones & Bartlett Learning.
Dictionary by Merriam-Webster: America's most-trusted online dictionary. (n.d.). Retrieved September
16, 2020, from https://www.merriam-webster.com/
Roper, N. (n.d.). Churchill Livingstone pocket medical dictionary.
Labonville, S. (2017, April 19). Generic vs. Brand: What's the Difference? Retrieved September 16, 2020,
from https://www.iwpharmacy.com/blog/generic-vs.-brand-whats-the-difference