Symptoms of neuroblastoma
Neuroblastoma may not cause any signs or symptoms in its early stages. Signs and symptoms often appear
once the tumour grows into surrounding tissues and will depend on the location of the tumour. Other health
conditions can cause the same symptoms as neuroblastoma.
Neuroblastoma most commonly develops in infants and children younger than 5 years old. It often starts in
the abdomen.
The most common signs and symptoms of neuroblastoma include:
a lump in the abdomen
a feeling of fullness or swelling in the abdomen
bulging of the eyes
dark circles around the eyes
bone pain
low levels of all 3 types of blood cells (called pancytopenia)
lumps or bumps in the skin that are sometimes blue
diarrhea
high blood pressure
fever
anemia
difficulty feeling or moving part of the body
a drooping eyelid and small pupil
Neuroblastoma can cause many different signs and symptoms depending on where it is in the body.
Neuroblastoma in the chest can cause chest pain, difficulty breathing, shortness of breath or cough.
Neuroblastoma in the neck can cause a lump in the neck or difficulty breathing.
Neuroblastoma affecting the spinal cord can cause weakness in the legs, difficulty walking, loss of bowel
or bladder control and spinal cord compression.
Spinal cord compression is a medical emergency that needs to be treated right away. It occurs when a
tumour puts pressure on the spinal cord. The pressure may cause swelling and sometimes the blood supply
to the spinal cord and nerves is affected. Spinal cord compression can lead to permanent paralysis if not
treated early. Find out more about spinal cord compression.