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Cefuroxime Drug Study

Cefuroxime is an antibiotic that inhibits bacterial cell wall synthesis. It has the following key points: - Mechanism of action is binding to penicillin-binding proteins to inhibit the final step of peptidoglycan synthesis in bacterial cell walls. - Used for prophylaxis of surgical infections in both adults and children. - Potential side effects include rash, fever, hearing loss, nausea, vomiting, and GI issues. - Contraindicated in those with a hypersensitivity to penicillin or mupirocin. Nursing considerations include assessing for allergic reactions, monitoring renal and liver function, and evaluating the therapeutic response.

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Arthur Christopher Corpuz
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129 views1 page

Cefuroxime Drug Study

Cefuroxime is an antibiotic that inhibits bacterial cell wall synthesis. It has the following key points: - Mechanism of action is binding to penicillin-binding proteins to inhibit the final step of peptidoglycan synthesis in bacterial cell walls. - Used for prophylaxis of surgical infections in both adults and children. - Potential side effects include rash, fever, hearing loss, nausea, vomiting, and GI issues. - Contraindicated in those with a hypersensitivity to penicillin or mupirocin. Nursing considerations include assessing for allergic reactions, monitoring renal and liver function, and evaluating the therapeutic response.

Uploaded by

Arthur Christopher Corpuz
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as DOCX, PDF, TXT or read online on Scribd
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REPUBLIC of the PHILIPPINES

City of Makati
COLLEGE OF ALLIED HEALTH STUDIES
J. P. Rizal Extension, West Rembo, Makati City 1215
Telephone No. : (+632) – 881 – 1571
_____________________________________________________________________________________
DRUG STUDY
Drug Name Mechanism of Action Indication Side Effects/Adverse Contraindication Nursing Consideration
Effect
Generic Name: Cefuroxime inhibits bacterial cell Prophylaxis of Surgical Rash, fever, pruritus, Hypersensitivity to - Assess the 12 Rights in Giving Medication
Cefuroxime wall synthesis by binding to one 1 Infections. erythema, urticaria, mupirocin.
Brand Name: or more of the penicillin-binding Stevens-Johnson - Special precautions to patients with history of
Zoltax proteins (PBPs) which in turn inhibit syndrome, erythema hypersensitivity to penicillin, and GI disease (particularly
Dosage the final transpeptidation step of multiforme, toxic colitis). Renal impairment. Pregnancy and lactation.
Parenteral peptidoglycan synthesis in bacterial epidermal necrolysis,
Prophylaxis of surgical cell walls, thus inhibiting cell wall serum sickness-like
- Monitor renal, hepatic and haematologic function periodically.
infections biosynthesis and arresting cell wall reactions, angioedema;
Monitor prothrombin time in patients at risk of prolongation.
Adult: 1.5 g IV before the assembly resulting in bacterial cell mild to moderate hearing
Observe for signs and symptoms of anaphylaxis during 1st dose.
procedure followed by 750 death. loss (childn); nausea,
- Evaluate therapeutic response.
mg IM 8 hrly for up to 24- vomiting, gagging,
48 hr depending on the Reference: epigastric burning, GI
procedure. MIMS 151st Edition 2017 bleeding and infection,
DRUG REFERENCE: abdominal pain).
https://www.mims.com/

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