Perio 3
Perio 3
PERIODONTICS NOTES 3
CEMENTUM These lines represent rest periods in cementum formation and are more
Normal Microscopic Features: mineralized than the adjacent cementum
- It is the calcified mesenchymal tissue that forms the outer covering of the Sharpey’s fibers make up most of the structures of acellular cementum,
anatomical root which has a principal role in supporting the tooth
Characteristics
Its fibers are inserted into the alveolar bone and into the cementum
Normal Clinical Features of Gingiva Its quite cellular, well innervated, vascular and contains epithelial
aggregates
Color
It occupies the narrow space between the calcified surfaces of the
The color of the attached and marginal gingivae is generally described
cementum and alveolus
as coral pink and is produced by the vascular supply, the thickness and
Is detectable in radiographs—a radioluscent line parallel to the root
degree of keratinization of the epithelium, and the presence of pigment-
surface (lamina dura in radiographs—radiodense line that represents
containing cells
the alveolar bone proper
DANIELLE ANN
PERIODONTICS NOTES 3
Varies in thickness—0.1 - 0.25 mm depending on age, stage of OSTEOCLASTS and ODONTOCLASTS –Osteoclasts work with
eruption of the tooth and functional characteristics osteoblasts to remodel existing alveolar bone. Odontoclasts can resorb
Thicker in adolescents than in older individuals mineralized dental tissue, including cementum
Teeth without antagonists would have thinner ligaments; with impacted EPITHELIAL CELLS – They are commonly found in the ligament close
teeth they’re even thinner to cementum. They originate from Hertwig’s epithelial root sheath
Under normal function tends to be narrowest near the middle of the root Undifferentiated mesenchymal cells OR PROGENITOR CELLS --
and wider near the apex These cells have a perivascular location within 5 micrometers of blood
vessels and a source of new cells for the periodontal ligament
Normal Microscopic Features MACROPHAGES –In the ligament are important defense cells because
The most important elements of the periodontal ligament are the of their phagocytic activity and mobility (take up bacteria, dead cells
principal fibers, which are collagenous, arranged in bundles, and follow and foreign bodies)
a wavy course when viewed in longitudinal section LEUCOCYTES – Individual leukocytes, specially small lymphocytes
Terminal portions of the principal fibers that insert into cementum and and plasma cells may appear in periodontium when it is stressed by
bone are termed Sharpey’s fibers disease
Transseptal Group – extend interproximally over the alveolar crest and
are embedded in the cementum of adjacent teeth Vascular Supply
Alveolar Crest Group – extend obliquely from the cementum just Compared with other connective tissues, the periodontal ligament is
beneath the Junctional epithelium to the alveolar crest and their exceptionally well vascularized, which reflects the high rate of turnover
function is to counterbalance the coronal thrust of the more apical of its cellular constituents
fibers, thus helping to retain the tooth within the socket and resists Its main blood supply is from the SUPERIOR AND INFERIOR
Horizontal Group – their fibers extend at right angles to the long axis of ALVEOLAR ARTERIES
the teeth from the cementum to the alveolar bone and function is
similar to alveolar crest group. They function to resist horizontal or Nerves
lateral pressures applied to the tooth crown The periodontal ligament contains both sensory and autonomic nerve
Oblique Group – largest group in the periodontal ligament, extends endings
from the cementum in a coronal direction obliquely to the bone and The sensory nerve endings are able to identify pain and pressure
bears the brunt of vertical masticatory stresses and transform them into The mechanoreceptors for pressure are extremely sensitive and are
tension on the alveolar bone able to detect minute particles between occluding tooth surfaces
Apical Group – they radiate from the cementum to the bone at the The autonomic innervation that originates from the superior cervical
fundus of the socket and not present in incompletely formed roots. It ganglion is primarily responsible for the control of smooth muscles
prevents vestibulo-oral tipping associated with the periodontal vasculature
Interradicular Fiber Group - Found only between roots of multirooted
tooth and running from the cementum into the bone forming the crest of Functions of Periodontal Ligament
the interradicular septum. It resists tipping and torque PHYSICAL
FORMATIVE
Other Fibers: NUTRITIVE AND SENSORY
Elastic fibers - this group of fibers are scarce and are confined to the loose
connective tissue surrounding neurovascular channels Physical
Oxytalan - is found interspersed among the collagen fibers, and is Transmission occlusal forces to the bone
morphologically similar to those in gingiva and run in an occluso-apical attachment of teeth to bone
direction associated with blood vessels and nerve fibers. They are found maintenance of the gingival tissues in their proper relationship to the
more often on the cemental than on the bony side of the ligament teeth
Indifferent fiber plexus - appears to course parallel to the root surface, resistance to the impact of occlusal forces (shock absorption)
forming a loose intersecting network and may also be incorporated into the provision of “soft tissue casing” to protect the vessels and nerves from
mineralized matrices injury by mechanical forces
Formative
Cells Periodontal ligament serves as the periosteum for cementum and bone
The main function of periodontal ligament cells is to maintain the normal Cells of the periodontal ligament participate in the formation and
organization of the fiber system by synthesizing new fibers and remove old resorption of cementum and bone which occur in physiologic tooth
ones movement
Generally the cellular density in periodontal ligament is greatest in young In the accommodation of the periodontium to occlusal forces and in the
individuals and decrease with age repair of injuries
Cellular density also increases with heavy function and decreases with lack Nutritive
of function The periodontal ligament supplies nutrients to the cementum, bone,
and gingiva by way of the blood vessels and provides lymphatic
Fibroblast drainage
They make up the major cellular population of the ligament Sensory
principal cells of the periodontal ligament The innervation of the periodontal ligament provides proprioceptive and
Their function is to synthesize collagen, which aggregates into fibrils tactile sensitivity which detects and localizes external forces acting
and fibers extracellularly upon the individual teeth and serves an important role in the
neuromuscular mechanism controlling the masticatory musculature
Cementoprogenitor And Osteoprogenitor Cells
CEMENTOBLASTS – Are observed during active deposition of cellular ANATOMY OF THE PERIODONTIUM
cementum
OSTEOBLASTS – Found in the peripheral part of the periodontal Periodontium
ligament adjacent to bone and seen where alveolar bone is deposited Attachment to bone tissue
hard tissue: Cementum; Alveolar Bone
Soft tissue: Gingival tissue ; Periodontal ligament
DANIELLE ANN
PERIODONTICS NOTES 3
Maintains the integrity of the surface mucosa • Represented as either transudate (normal state) or exudate (pathologic
attachment apparatus/ supporting tissue of teeth state)
Undergoes change with age • Contains a vast array of biochemical factors
morphologic change • Components of connective tissue, epithelium, inflammatory cells,
serum and microbial flora
3 Zones of Oral Mucosa • Marker by checking the microbial flora
Masticatory – Gingiva| Covering of hard palate
Specialized – Dorsum of the tongue (Taste buds) Functions:
Lining mucosa - Ventral part of tongue Cleanse material from sulcus
Vestibule Contains plasma proteins that may improve adhesion of
Buccal periosteum epithelium to tooth
Gingiva Possess antimicrobial property
Frenum Exert antibody activity to defend the gingiva
Floor of the mouth
Soft Palate Clinical Features of Gingiva
• Color – coral pink produced by the vascular supply, thickness and
Gingiva degree of keratinization of the epithelium
• Marginal gingiva • Size – correspond s with the sum total of the bulk of cellular and
– Not attached ; where calcular deposit is lovated intracellular elements and their vascular supply
• Attached gingiva • Contour – depends on the size of the tooth tooth and their alignment in
– Attached on alveolar bone the arch.
• Alveolar mucosa • Shape – interdental gingiva – triangular
– Darker in color than the attached gingiva • Consistency – firm and resilient
• Mucogingival junction • Surface texture - stippled
– Changes in color is observed
Characteristics Periodontal Ligament
Highly vascular • is composed of a complex vascular and highly cellular connective
Color: coral pink tissue that surrounds the tooth root and connects it to the inner wall of
Appearance: stippled the alveolar bone.
Texture: firm
Surface: dull Periodontal Fibers
Rounded: Specially on the marginal • The terminal portions of the principal fibers that are inserted into
1.5 -2mm from coronal to CEJ cementum and bone are termed Sharpey’s fibers
• The most important elements of the periodontal ligament are the
Function and features of gingival epithelium principal fibers, which are collagenous and arranged in bundles and
Function follow a wavy course when viewed in longitudinal section
Mechanical, chemical, water and microbial barrier, signaling
functions Collagen
Architechural Integrity • is a protein composed of different amino acids, the most important of
Cell-cell attachments which are glycine, proline, hydroxylysine, and hydroxyproline.
Basal cell lamina • responsible for maintenance of the framework and tone of tissue, and it
Keratin cytoskeleton exhibits a wide range of diversity
Major Cell Type • is synthesized by fibroblasts, chondroblasts, osteoblasts, odontoblasts,
Keratinocyte and other cells.
Other Cell Types
Langerhans cells Principal Fibers of PDL
Melanocytes, Merkel cells • Transseptal Group
Constant Renewal • Alveolar Crest Group
Replacement of damaged cells • Horizontal Group
Cell-cell attachments • Oblique Group
Desmosomes, adherens junctions, tight junctions, gap junctions • Apical Group
Cell-Basal Lamina • Interradicular Group
Synthesis of basal lamina components
Hemidesmosome Transseptal Group
Transseptal fibers extend interproximally over the alveolar bone
Gingival Epithelium crest and are embedded in the cementum of adjacent teeth
Junctional Epithelium Alveolar Crest Fibers
• Close attachment to enamel Alveolar crest fibers extend obliquely from the cementum just
Sulcular epithelium beneath the junctional epithelium to the alveolar crest
• Found on sulcus Horizontal Group
**Sulcus – triangular shaped Horizontal fibers extend at right angles to the long axis of the
Interdental Gingiva tooth from the cementum to the alveolar bone
• Triangular Oblique Group
• Usually violated during dental treatment Oblique fibers, the largest group in the periodontal ligament,
extend from the cementum in a coronal direction obliquely to the
Gingival Fluid or Sulcular Fluid bone
Apical Group
DANIELLE ANN
PERIODONTICS NOTES 3
The apical fibers radiate in a rather irregular manner from the • Attaches the periodontal ligament fibers to the root
cementum to the bone at the apical region of the socket. They do • Contributes to the process of repair after damage to the root surface
not occur on incompletely formed roots
Interradicular Group Alveolar Process
The interradicular fibers fan out from the cementum to the tooth in • Parts of the maxilla and the mandible that form and support tahe
the furcation areas of multirooted teeth. Other well-formed fiber sockets of the teeth
bundles interdigitate at right angles or splay around and between • Consists of bone
regularly arranged fiber bundles • Bone Dehiscence- complete removal of bony part
• Fenestration- Marginal bone is still intact
Cellular Elements
• Four types: AGING AND PERIODONTIUM
Connective tissue cells Effects of aging on the periodontium
Epithelial rest cells • Gingival epithelium
Immune system cells • Gingival connective tissue
Cells associated with neurovascular elements • Periodontal ligament
• Cementum
Connective Tissue Cells • Alveolar bone
include fibroblasts, cementoblasts, and osteoblasts.Fibroblasts • Bacterial plaque
are the most common cells in the periodontal ligament and • Gingival epithelium – thinning and decreased keratinization of gingival
appear as ovoid or elongated cells oriented along the principal epithelium
fibers, exhibiting pseudopodia-like processes. • Gingival connective tissue - coarser and denser gingival connective
Epithelial Rest of Malassez tissue
form a latticework in the peri- odontal ligament and appear as • Periodontal ligament – decreased numbers of fibroblasts and more
either isolated clusters of cells or interlacing strands, depending irregular structure
on the plane in which the microscopic section is cut. Continuity o Decreased organic matrix production and epithelial cell rests
with the junctional epithelium has been suggested in experimental o Increased amount of elastic fiber
animals. Cementum – increased in cememtal width
Alveolar bone - more irregular periodontal surface of bone
Epithelial Rest Less regular insertion of collagen fibers
are distributed close to the cementum throughout the periodontal Bacterial plaque – dentogingival plaque accumulation
ligament of most teeth and are most numerous in the apical area Subgingival plaque – increased number of enetric rods and
and cervical area pseudomonads
diminish in number with age by degenerating and disappearing or
by undergoing calcification to become cementicles. The cells are Response to treatment of the periodontium
surrounded by a distinct basal lamina, are interconnected by • Both meticulous homecare plaque control by the patient and meticulous
hemidesmosomes, and contain tonofilaments. supragingival and subgingival debridement of the therapist
Ground Substance
also has a high water content (70%). The cell surface CLASSIFICATION OF DISEASES AND CONDITIONS AFFECTING
proteoglycans participate in several biologic functions, including PERIODONTIUM
cell adhesion, cell-cell and cell-matrix interac- tions, binding to Classification of Diseases and Conditions affecting periodontium
various growth factors as co-receptors, and cell repair. Gingival Disease
Chronic Periodontitis
Types of components of Ground Substance Aggressive Periodontitis
• Glycosaminoglycans Periodontitis as a Manifestation of Systemic Diseases
• Hyaluronic Acid Abscesses of the Periodontium
• Proteoglycans Periodontitis Associated with Endodontic Lesions
• Glycoproteins Developmental or Acquired Deformities and Conditions
• Fibronectin
• Laminin Gingival Disease
I. Plaque-induced gingival diseases
The periodontal ligament may also contain calcified masses called II. Non-plaque-induced gingival lesions
cementicles, which are adherent to or detached from the root surfaces Chronic Periodontitis
I. Localized
Functions of Periodontal Ligament II. Generalized
• The functions of the periodontal ligament are categorized into physical, Aggressive Periodontitis
formative and remodeling, nutritional, and sensory. I. Localized
Physical Functions Of The Periodontal Ligament Entail The Following: II. Generalized
1. Provision of a soft tissue “casing” to protect the vessels and nerves Periodontitis as a Manifestation of Systemic Diseases
from injury by mechanical forces. I. Necrotizing Periodontal Diseases
2. Transmission of occlusal forces to the bone. I. Necrotizing Ulcerative Gingivitis (NUG)
3. Attachment of the teeth to the bone. Cementicles in the periodontal II. Necrotizing Ulcerative Periodontitis (NUP)
ligament, one lying free and the other adherent to the tooth surface. Abscesses of the Periodontium
4. Maintenance of the gingival tissues in their proper relation- ship to o Gingival abscess
the teeth. o Periodontal abscess
5. Resistance to the impact of occlusal forces (shock absorption) o Pericoronal abscess
Periodontitis Associated with Endodontic Lesions
Cementum o Endodontic- Periodontal Lesion
DANIELLE ANN
PERIODONTICS NOTES 3
o Periodontal- Endodontic Lesion 1. Usually affects persons under 30 years of age
o Combines Lesion 2. Generalized interproximal attachment loss affecting at least 3
Developmental or Acquired Deformities and Conditions permanent teeth other than first molars and incisors
o Localized tooth-related factors that predispose to plaque-induced 3. Pronounced episodic nature of destruction of attachment and alveolar
gingival diseases or periodontitis bone
o Mucogingival deformities and conditions around teeth 4. Poor serum antibody response to infecting agents
o Mucogingival deformities and conditions on edentulous ridges
o Occlusal trauma PERIODONTITIS AS A MANIFESTATION OF SYSTEMIC DISEASE
• Formed by occlusion or trauma to the orifice of the periodontal pocket,
resulting in extension of the infection from the pocket into the soft tissue
GINGIVAL DISEASES
of the pocket wall.
A. Plaque Induced Gingival Disease
- The result of interaction between the microorganism found in the
dental plaque biofilm and the tissues and inflammatory cells of the host
A.1. Gingival Dieseases modified by systemic factors
1.1 Associated with the endocrine system
- Puberty, menstruation, pregnancy, diabetes mellitus
1.2 Associated with blood dyscrasias
- Leukemia, others
A.2. Modified by Medications
2.1 Gingival enlargements
2.2 Gingivitis
A.3. Modified by Malnutrition
B. Non-Plaque induced Gingival Lesion
B.1 Specific Bacterial Origin
- neisseria gonorrhea, pallidum, streptococcus
B.2. Viral Origin
- PHG, recurrent oral herpes, varicella zoster
B.3. Fungal Origin
- Candida, Histoplasmosis
B.4. Lesions of Genetic Origin
- Hereditary gingival fibromatosis
B.5. Manifestations of systemic conditions
5.1 Mucocutaneous lesions
- Lichen planus, pemphigoid, erythema,
lupus, drug induced
5.2 Allergic Reactions
- Dental restorative materials
-Toothpastes, mouthrinses, additives,
food
B.6. Traumatic Lesions
B.7. Foreign Body Reactions
CHRONIC PERIODONTITIS
Clinical Features
1. More prevalent in adults
2. Amount of periodontal destruction is commensurate with oral hygiene,
local predisposing factors, systemic risk factors
3. Microbial plaque is complex
4. Localized- 30% of sites are affected
5. Host factors influence the pathogenesis and progression of disease
6. Progression can only be confirmed by repeated clinical exam and likely
to occur in diseased sites left untreated
Extent of Disease
• Low category- involve 1-10 sites
• Medium category- 11-20 sites
• High category- more than 20 sites
Severity of the Disease
• Mild- 1-2mm CAL
• Moderate- 2-3mm CAL
• Severe- ≥5mm CAL
AGGRESSIVE PERIODONTITIS
Localized Aggressive Periodontitis
1. Circumpubertal onset
2. Localized first molar/ incisor presentation
3. Robust serum antibody response to infecting agents
Generalized Aggressive Periodontitis