DRUG SPECIFIC ACTION INDICATION CONTRAINDICATION ADVERSE EFFECTS NURSING RESPONSIBILITIES

Generic Name: It exhibits analgesic -Mild to moderate pain -Contraindicated in CNS: nausea, drowsiness, Assessment & Drug Effects:
Paracetamol, action by peripheral and fever patients hypersensitive to stimulation. - Assess patient’s fever or pain: type of
Acetaminophen blockage of pain drug. pain, location, intensity, duration,
impulse generation. It -Reduce fever in viral and GI: Vomiting, abdominal temperature, and diaphoresis.
Classification: produces antipyretic bacterial infections -Use cautiously in pain. -Assess allergic reactions: rash,
Non-narcotic effect by inhibiting the patients with long-term urticaria; if these occur, drug may have
analgesic, hypothalamic heat- alcohol use because Hepatic: hepatotoxicity, to be discontinued.
Antipyretic regulating centre. Its therapeutic doses cause hepatic seizure(overdose)
weak anti- hepatotoxicity in these Drug administration:
Dosage: inflammatory activity is patients. Renal: Renal failure(high, -Verify patient’s identity
600mg IVTT q 6 hrs related to inhibition of prolonged doses) - Administer the right drug with the
prostaglandin synthesis right dose at the right time
Route: in the CNS. Hematology: leukopenia, -State importance and purpose of the
IVTT neutropenia, hemolytic drug to the patient
anemia (long term use) -If hypersensitivity reaction occurs,
Frequency: thrombocytopenia, stop the administration immediately
RTC pancytopenia.

Skin: rash, urticaria, Patient & Family Education:

hypersensitivity, cyanosis, -Teach patient to recognize signs of
anemia, jaundice, chronic overdose: bleeding, bruising,
malaise, fever, sore throat.
-Tell patient to notify prescriber for
pain/ fever lasting for more than 3 days.
-Avoid alcohol.
 DRUG SPECIFIC ACTION INDICATION CONTRAINDICATION ADVERSE EFFECTS NURSING RESPONSIBILITIES
Systemic
Generic Name: Inhibits protein -Treatment of serious -Contraindicated in Assessment & Drug Effects:
Clindamycin synthesis in susceptible infection caused by patients hypersensitive to CNS: Cardiac arrest (with - Check doctor’s order
bacteria, causing cell susceptible stains of drug. rapid IV transfusion) - Assess for hypersensitivity of the
Classification: death anaerobes drug, history of asthma or other
Lincosamide -Use cautiously in GI: Pseudomembranous allergies, allergies to tartrazine
Antibiotic Onset: Immediate patients in patients with colitis - Assess history of renal impairment,
tartrazine sensitivity or lactaction, regional enteritis or
Dosage: Peak: Minutes hepatic or renal Hypersensitivity: rashes ulcerative colitis
300mg impairment
Duration: 8-12 hrs Local: Pain following Drug administration:
Route: Interactions: injection, thrombophlebitis -Verify patient’s identity
IVTT Metabolism: hepatic, 2- Drug to drug: increased after IV use - Administer the right drug with the
3 hrs neuromuscular blockade right dose at the right time
Frequency: with neuromuscular Renal: Urinary frequency -State importance and purpose of the
q 8 hrs Distribution: Crosses blocking agents; drug to the patient
placenta, enters breast decreased GI absorption - Check patency of the IV site and line
milk with Kaolin, aluminum Hematology: leukopenia, -If. Hypersensitivity reaction occurs,
salts neutropenia stop the administration immediately
Excretion: Feces, urine
Skin: Contact dermatitis,
Topical: Minimal dryness After:
systematic absorption -Regulate IVF with the prescribed
flowrate
-Monitor LFT’s renal function tests and
blood count
-Report severe or watery diarrhea,
abdominal pain, inflamed mouth or
vagina, skin rash or lesions
-Take full prescribed course of oral
drug. Do not stop taking without
notifying your health care provider
-Document and record.
 DRUG SPECIFIC ACTION INDICATION CONTRAINDICATION ADVERSE EFFECTS NURSING RESPONSIBILITIES
Systemic
Generic Name: Inhibits cell-wall -Systematic infections -Contraindicated in Assessment & Drug Effects:
Oxacillin synthesis during caused by penicillinase- patients hypersensitive to CNS: Headache with severe - Check doctor’s order
microorganism producing staphylococci drug. blistering - Assess for hypersensitivity of the drug
Classification: multiplication and allergies to cephalosporins
Penicillin GI: Diarrhea that is watery - Assess history of renal impairment,
or bloody lactaction.
Dosage: -Obtain specimen for culture and
1gm Hypersensitivity: rashes sensitivity tests before first dose

Route: Local: Fever, sore throat, Drug administration:

IVTT chills, bodyache - Give 1-2 hours before or 2-3 hours
after meals to prevent gastric irritation
Frequency: Renal: urinating less than - Verify patient’s identity
q 6 hrs usual or not st all - Administer the right drug with the
right dose at the right time
-State importance and purpose of the
Hematology: easy bruising drug to the patient
or bleeding - Check patency of the IV site and line
-If Hypersensitivity reaction occurs,
Skin: Peeling and redness, stop the administration immediately
skin rash

After:
-Regulate IVF with the prescribed
flowrate
-Monitor LFT’s renal function tests and
blood count
-Report if symptoms persists.
-Document and record.
 DRUG SPECIFIC ACTION INDICATION CONTRAINDICATION ADVERSE EFFECTS NURSING RESPONSIBILITIES
Systemic
Generic Name: Inhibits cell-wall Uncomplicated and -Contraindicated in Assessment & Drug Effects:
Piperacillin synthesis during complicated skin and skin patients hypersensitive to CNS: Pain, headache, - Check doctor’s order
microorganism structure infections, drug. insomnia, agitation, fever, - Assess for hypersensitivity of the drug
Classification: multiplication; infections caused by beta- dizziness, anxiety and to other drugs
Penicillin antibiotic Tazobactam increases lactamase producing -Use cautiously in - Assess history of renal impairment
piperacillin isolates of patients in patients with CV: hypertension,
Dosage: effectiveness by Staphylococcus aureus other drug allergies, tachycardia, chest pain, Drug administration:
4.5 gms inactivating beta- especially to edema -Verify patient’s identity
lactamase which cephalosporins and in -Position client in high fowlers to
Route: destroys penicillins. those with bleeding GI: Diarrhea, nausea, prevent aspiration
IVTT Onset: Immediate tendencies, uremia or constipation, vomiting, - Administer the right drug with the right
hypokalemia. dyspepsia, stool changes, dose at the right time
Frequency: Peak: Minutes abdominal pain -State importance and purpose of the
q 8hr drug to the patient
Duration: 8-12 hrs Hypersensitivity: rashes - Check patency of the IV site and line
-If. Hypersensitivity reaction occurs,
Metabolism: hepatic, 2- Renal: Urinary frequency stop the administration immediately
3 hrs
Respiratory: Dyspnea
Distribution: Crosses After:
placenta, enters breast Hematology: -Regulate IVF with the prescribed
milk Thrombocytopenia flowrate
-Check placement of NGT
Excretion: Feces, urine -Monitor LFT’s renal function tests and
blood count
Topical: Minimal -Report severe or watery diarrhea,
systematic absorption abdominal pain, inflamed mouth or
vagina, skin rash or lesions
-Monitor adverse reactions
-Document and record.