Independent University, Bangladesh
Assignment
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“…………………”
Submitted by:
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Submitted to:
Shimul Halder, Ph.D. (Japan)
Adjunct Faculty, Department of Pharmacy,
Independent University, Bangladesh
&
Associate Professor Dept. of Pharmaceutical Technology
Faculty of Pharmacy
University of Dhaka, Bangladesh
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(25 September 2021)
Department of Pharmacy
Independent University Bangladesh
Theory and classification of IR
spectroscopy
Introduction
Infrared (IR) spectroscopy is one of the most common and widely used spectroscopic
techniques. Absorbing groups in the infrared region absorb within a certain wavelength
region. The absorption peaks within this region are usually sharper when compared
with absorption peaks from the ultraviolet and visible regions. In this way, IR
spectroscopy can be very sensitive to determination of functional groups within a
sample since different functional group absorbs different particular frequency of IR
radiation. Also, each molecule has a characteristic spectrum often referred to as the
fingerprint. A molecule can be identified by comparing its absorption peak to a data
bank of spectra. IR spectroscopy is very useful in the identification and structure
analysis of a variety of substances, including both organic and inorganic compounds. It
can also be used for both qualitative and quantitative analysis of complex mixtures of
similar compounds.
Infrared spectroscopy is the spectroscopy which is concerned with the study of infrared
region of electromagnetic spectrum (i.e. light having a longer wavelength & a lower
frequency than visible light), which results in vibrational transitions i.e. Study of
interaction between infrared radiations & matter.
• It is also called as vibrational spectroscopy.
• Vibrations in IR spectroscopy also known as fundamental vibrations.
• The IR spectroscopy concept can be generally analysed in 3 ways:
* By measuring reflection
* By measuring emission
* By measuring absorption
• It is an important qualitative analytical technique for determining the structure of both
organic & inorganic compounds.
• IR radiations lies in the wavelength range of 0.7-400 μm
• Infrared radiations refers broadly to that part of electromagnetic spectrum between
visible & microwave region.
• It is based on the absorption spectroscopy in which molecular vibration is observed
due to absorption of IR radiation.
• It measures the bond vibration frequencies in a molecule.
The use of infrared spectroscopy began in the 1950's by Wilbur Kaye. He had designed
a machine that tested the near-infrared spectrum and provided the theory to describe the
results. Karl Norris started using IR Spectroscopy in the analytical world in the 1960's
and as a result IR Spectroscopy became an accepted technique. There have been many
advances in the field of IR Spec, the most notable was the application of Fourier
Transformations to this technique thus creating an IR method that had higher resolution
and a decrease in noise. The year this method became accepted in the field was in the
late 1960's.
Theory Of IR