DRUG NAME CLASSIFICATION MECHANISM OF INDICATIONS CONTRAINDICATIONS SIDE/ADVERSE NURSING

ACTION EFFECTS RESPONSIBILITIES

Generic THERAPEUTIC: INDICATIONS: Hypersensitivity to SIDE EFFECTS: BEFORE:
name: Anti-anginal; Selective -Used for the trimetazidine • Monitor vital signs
Trimetazidine Antihyperten inhibition of an treatment, before giving the
sive enzyme of fatty prevention, Dizziness medications.
Complete acid β-oxidation: control and or • Low Assess for signs and
Prescription PHARMACOLOGIC: the long-chain 3- improvement of blood pressure symptoms of heart
35mg 1tab Calcium Channel ketoacyl CoA the following with change of failure.
BID Blocker thiolase (3-KAT). diseases such position DURING:
This inhibition as severe pain • Pruritus Administer right drug
results in: in chest. • Nausea to the right patient
Reduction in - acute anginal • Vomiting with the right dose,
fatty acid attacks and frequency.
oxidation; - prevent ADVERSE AFTER:
Stimulation of situation EFFECTS: Document and record
glucose that may cause • Allergic accordingly
oxidation. anginal attacks skin reaction Observe patient for
such as rashes adverse reactions.
The coupling of Notify physician if
glycolysis with adverse reactions are
glucose uncontrolled.
oxidation is
improved and
ATP production
is further
increased, while
cell acidosis and
Ca2+ overload
are limited. The
increase in total
glucose
utilization has
been evidenced
by studies using
18FDG positron
emission
tomography
(PET).
Therapeutic
action:
Improves
myocardial
glucose
utilization
through inhibition
of fatty acid
metabolism, also
known as fatty
acid oxidation
inhibitor.