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PATHOLOGY ASSIGNMENT 4 (Renal System)

Red renal infarcts appear acutely after vascular occlusion and appear wedge-shaped and red due to hemorrhage within the kidney, while white infarcts appear later as they lose hemoglobin causing a pale appearance as the necrotic tissue is replaced by fibrous scar tissue over two to three days. The document provides details on the distinguishing gross and histological features of acute red versus subacute/chronic white renal infarcts.

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22 views3 pages

PATHOLOGY ASSIGNMENT 4 (Renal System)

Red renal infarcts appear acutely after vascular occlusion and appear wedge-shaped and red due to hemorrhage within the kidney, while white infarcts appear later as they lose hemoglobin causing a pale appearance as the necrotic tissue is replaced by fibrous scar tissue over two to three days. The document provides details on the distinguishing gross and histological features of acute red versus subacute/chronic white renal infarcts.

Uploaded by

nyarie
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© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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UNIVERSITY OF ZIMBABWE

FACULTY OF VETERINARY SCIENCE


PARACLINICAL DEPARTMENT
COURSE : PATHOLOGY

NAME : NGONGONI LLOYD ANESU

REG NUMBER : R1711634

DEADLINE : 24 JUNE 2020

LECTURER : DR VHORI

QUESTION

DISTINGUISH RED INFARCTS FROM WHITE AS IT APPLIES TO


THE KIDNEY (10).

COMMENTS
……………………………………………………………………………………
……………………………………………………………………………………
Renal infarcts are areas of coagulative necrosis that result from local ischaemia or vascular
blockage and usually are due to thromboembolism. Grossly, renal infarcts appear red or pale
white depending on several factors, including the interval after vascular occlusion that is age
of infarct.

Type of infarcts Red infarcts White infarcts


Age Initial stage of renal Appears two to three day later
infarction (Acute) (Subacute, Chronic) because of
lysis of erythrocytes and loss of
haemoglobin.
Aetiology  Occlusion of small interlobular arteries probably due to
thromboembolism.
 Local ischaemia.
Gross appearance  Acutely, infarcts are  Subacute infarcts are pale and
usually wedge-shaped in a surrounded by a rim of active
cross section of the hyperaemia, the cortical
kidney, red due to surface of many but not all, of
haemorrhage and the the infarcts is even with that
infarct bulges above the of the adjacent unaffected
capsular surface due to areas of the cortex, indicating
cell swelling. cell swelling has subsided.
 Chronic infarcts are pale scars
of fibrous connective tissue.
Histological Nephrons (including tubules, The margin of the necrotic zone
appearance glomeruli, and interstitium) in contains an inflammatory
the central zone of the infarct infiltrate consisting largely of
are necrotic. neutrophils and fewer
macrophages and lymphocytes.
Capillaries adjacent to the
necrotic area are notably
engorged with blood
(hyperaemia).
References
Zachary, J. F (2017), Pathologic Basis of Veterinary Disease, 6th edition, Elsevier Mosby, St
Louis Missouri.

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