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BP501TT - Medicinal Chemistry

This document is an exam for a Medicinal Chemistry course, consisting of 7 questions testing knowledge of various drug classes and medicinal compounds. It begins by providing exam details such as the date, time limit, and total marks. The questions cover topics like drug classification, synthesis, structure-activity relationships, and mechanisms of action. Students are instructed to attempt any 5 of the 7 questions, which range from 5-6 marks each and include sub-questions requiring drug structures, classifications, summaries, and explanations.

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Uttam A. More
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77 views1 page

BP501TT - Medicinal Chemistry

This document is an exam for a Medicinal Chemistry course, consisting of 7 questions testing knowledge of various drug classes and medicinal compounds. It begins by providing exam details such as the date, time limit, and total marks. The questions cover topics like drug classification, synthesis, structure-activity relationships, and mechanisms of action. Students are instructed to attempt any 5 of the 7 questions, which range from 5-6 marks each and include sub-questions requiring drug structures, classifications, summaries, and explanations.

Uploaded by

Uttam A. More
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
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Seat No.: _____ Enrolment No.

_____________

GUJARAT TECHNOLOGICAL UNIVERSITY


B.Pharm- SEMESTER–V EXAMINATION – WINTER -2021

Subject Code: BP501TT Date:13/12/2021


Subject Name: Medicinal Chemistry-II
Time: 10:30am to 01:30pm Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Classify H1-receptor antagonists. Write the structure and use of one drug from 06
each category.
(b) Write a short note on gastric proton pump inhibitors. 05
(c) Write structure and use of following drugs: 05
(a) Ethacrynic acid (b) Benzocaine (c) Metformin (d) Ranitidine
(e) Cetrizine
Q.2 (a) Classify corticosteroids with suitable examples. Write chemical structure of any 06
one drug from each category.
(b) Write an informative note on anti-angial agents. 05
(c) Write a short note on oral anticoagulants. 05
Q.3 (a) What are diuretics? Classify diuretics with examples. Give synthesis of 06
Acetazolamide.
(b) Classify antihyperlipidemic agents with suitable examples and structures in 05
each category.
(c) Write a short note on drugs used for erectile dysfunction. 05
Q.4 (a) What are anti-neoplastic agents? Classify them and write about any one class in 06
detail.
(b) What is Diabetes Mellitus? Write chemical classification of oral hypoglycemic 05
agents with suitable examples and structures in each category.
(c) Outline synthetic scheme and use of following drugs (Any two): 05
(a) Methotrexate (b) Warfarin (c) Tolbutamide
Q.5 (a) Outline the SAR of local anesthetics. 06
(b) What are antihypertensive agents? Classify them and write two chemical 05
structures of each class.
(c) Define and classify anti-arrhythmic agents and explain mode of action of each 05
class.
Q. 6 (a) Write a short note on H2-receptor antagonists. 06
(b) Define and classify antithyroid drugs. Give chemical structure of any one drug 05
from each category.
(c) Write a short note on oral contraceptives. 05
Q.7 (a) What are hormones? Discuss nomenclature and stereochemistry of steroids. 06
(b) Write a short note on Angiotensin Converting Enzyme inhibitors. 05
(c) Write in detail 1,4-dihydropyridine calcium channel blockers. 05

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