Meiosis

Presented by:-
Dr. Madhu gupta

SOS IN BOTANY
JIWAJI UNIVERSITY GWALIOR
Contents
• What is Meiosis cell division
• History of meiosis
• Where it occurs?
• Phases of meiosis-I
• Crossing over & importance
• Phases of meiosis-II
• Importance of meiosis
 What is meiosis cell division?
• Meiosis is a special type of cell division
necessary for Sexual Reproduction.
• Meiosis begins with one diploid cell co
ntaining two copies of each chromoso
me.
• One from the organism’s mother and o
ne from it’s father.
• Produces for haploid cells containing o
ne copy of each chromosome.
History of meiosis
• Meiosis was discovered and described for the fir
st time in Sea Urchin eggs in 1876 by the Germa
n biologist Oscar Hertwig.

• It was described again in 1883, at the level of ch

romosomes, by the Belgian zoologist Edouard V
an Beneden in Ascaris worm’s eggs.

• The term “Meiosis” was coined by J.B. Farmer a

nd J.B. Moore in 1905.
Where it occurs?

• Meiosis occurs in eukaryotic life cycles involvin

g sexual reproduction.
• It always occur in reproductive cells.
• In lower plant meiosis occur after fertilization i
n zygote.
• In higher plant it occurs before fertilization in t
he time of gamete formation.
Phases of meiosis-I & meiosis-II
Prophase-I • Prophase-II
-Leptotene • Metaphase-II
-Zygotene • Anaphase-II
-Pachytene • Telophase-II
-Diplotene
-Dikinesis
Metaphase-I
Anaphase-I (Meiosis-II is the mitotic division
of 2 haploid cells to produce 4
Telophase-I haploid daughter cells)
Prophase-I

• During prophase-I, DNA is exchanged between homologous ch

romosomes in a process called homologous recombination. T
his often results in chromosomal crossover.
• The paired and replicated chromosomes are called bivalents o
r tetrads.
• The process of pairing the homologous chromosomes are call
ed Synapsis.
• At this stage, non-sister chromatids may cross-over at point ca
lled Chiasmata.
 Leptotene

• The first stage of prophase-I is the Leptote

ne stage.
• Leptotene (Greek; Leptonema- thin thread
s)
• During this stage, individual chromosomes
begin to condense into long strands within
the nucleus.
• However, the two sister chromatids are sti
ll so tightly bound that they are indistingui
shable from one another.
Zygotene

• Zygotene (Greek; zygonema- pair

ed threads)
• Zygotene, occurs as the chromos
omes approximately line up with
each other into homologous chro
mosomes.
• The combined homologous chro
mosomes are said to be bivalent.
Pachytene
• In pachynema, the homologous chromosomes become much m
ore closely associated. This process is known as Synapsis.
• The synapsed homologous pair of chromosomes is called a tetra
d, because it consists of four chromatids.
• It can’t be observed until the next stage, but the synapsed chro
mosomes may undergo crossing over in pachynema.
• The chromosomes continue to condense.
Diplotene
• Diplotene (Greek; diplonema- two threads)
• In this stage, crossing over takes place.
• The homologous chromosomes separete from one another litt
le.
• Nuclear membrane and nucleolus begins to disappear.
Diakinesis
• Chromosomes condense further during the diakinesi
s stage.
• In this stage, the homologous chromosomes separat
e further, and the chiasma terminalize due to contrac
tion of the tetrad.
• Spindle fibre begin to form.
 Crossing over

• Crossing over is a process by wh

ich two chromosomes of a hom
ologous pair exchange equal se
gments with each other.
Importance-
1. Produces new combinations of traits.
2. Helps in mapping of chromosomes.
3. Selection of useful recombinations.
Metaphase-I
• Metaphase-I is the second phase of meiosis.
• The spindle fibres organized between two poles and
get attached to the centromere of chromosomes.
• Chromosomes moves to equater.
Anaphase-I
• Anaphase-I begins when the two chromosomes of ea
ch bivalent separate and start moving toward opposit
e poles.
• In this stage, the sister chromatids remain attached a
t their centromeres and move together toward the p
oles.
Telophase-I
• The homologous chromosome pairs reach the poles of the cell
.
• The homologous chromosome pairs complete their migration
to the two poles.
• A nuclear envelope reforms around each chromosome set, th
e spindle disappears, and cytokinesis follows.
 Prophase-II

• Meiosis-II begins without any further r

eplication of the chromosomes. The n
uclear envelope breaks down and the
spindle apparatus forms.
• The dyads chromosome becomes thick
er and shorter.
• Nuclear membrane and nuceolus disa
ppear.
• Spindle fibre starts to form.
Metaphase-II
• Centromeres are arranged in aline called equa
torial plate of invisible spindle apparatus.
• Spindle fibres organize between poles and att
aches to centromere of chromosome.
Anaphase-II
• Centromere of each chromosome divides and
sister chromatids separates to form two daug
hter chromosome.
• Spindle fibre contracts and pull the daughter c
hromosome apart towards opposite pole.
Telophase-II
• Nuclear envelope forms around each set of chromosomes.
• Nucleolus appears in each nucleus.
• Chromosome elongates to form thin networks of chromatin.
• Nuclear membrane and nucleolus reappears.
 Importance of meiosis

1. Produces haploid gametes so that the diploid num

ber of the species remains constant generation afte
r generation.

2. Source of genetic variation because crossing-over b

rings together new gene combination on chromoso
me.
 conclusion
• Meiosis is the reductional cell division occurs in germ cells produci
ng four cells of half chromosome number from that of parent cell .
• Nucleus divides twice in meiosis-I and meiosis-II.
• Meiosis-I involves the separation of homologous(reduction division
) while in meiosis –II , separation of chromatids occur (equational d
ivision).
• To maintain the chromosome number constant in a sexually reprod
ucing species , meiosis is essential .
 References
• Sen, sumitra,dipak kumar kar,”Cytology and genetics”,N
arosa publishing house.

• Sinha.U, Sunita sinha,2nd rev.”Cytogenetics, plant breedi

ng and evolution”, Vikas Publishing House Pvt. Ltd.

• Internet : www. Biologydiscussion.com