KRISHNA INSTITUTE OF MEDICAL SCIENCES “ DEEMED TO BE UNIVERSITY ”, KARAD.

II MBBS 1st Internal Assessment Examination, May, 2021

PATHOLOGY – Theory Paper
Date: 4-5-2021 Total Marks : 100
Time: 1.30 pm. to 4.30 pm.

Instructions:- 1) Each MCQ carries 1 mark

2) Avoid overwriting & / or striking of answers once written.

Section A

Q.No.1 MCQs (1 mark x 20 Q.) Marks: 20

1) The Father of Modern Pathology is

a) Robert Kock b) William Harvey c) Rudolph Virchow d) Louis Pasteur
2) Special fixative for Electron microscope is
a) Alcohol b) Picric acid c) Bouin’s fluid d) Glutaraldehyde
3) The special stain for demonstration of fat is

a) Sudan IV b) PAS c) Congo red d) Reticulin stain

4) FNAC is

a) Study of paraffin embedded tissue b) Study of the cells aspirated by fine needle

c) Study of detached cells from natural passages d) Done to diagnose carcinoma cervix.

5) Programmed destruction of cells is called as

a) Infarction b) Gangrene c) Apoptosis d) Necrosis

6) Desmoplasia is
a) Increase in dense fibrous stroma b) Increase in number of parenchymal cells.
c) Increase in number of fat cells d) Increase in number of mitosis
7) Myocardial infarction is an example of
a) Coagulative necrosis b) Liquifactive necrosis c) Caseous necrosis d) Fibrinoid necrosis.
8) Malignant neoplasm of epithelial cell origin is called as

a) Sarcoma b) Fibroma c) Carcinoma d) Carcinosarcoma

9) Caisson’s disease is an example of

a) Embolism b) hemorrhage c) Infarction d) Thrombosis

10) Activation of cytokine cascade is characteristic of

a) Septic shock b) Hypovolemic shock c) Neurogenic shock d) Cardiogenic shock

11) Anaphylactic shock is mediated by

a) Failure of the myocardial pump b) Loss of blood

c) Type I Hypersensitivity response d) Release of endotoxins
12) Granulomas are demonstrable in all EXCEPT

a)Tuberculosis b) Sarcoidosis c) Pyogenic inflammation d) Reaction to foreign body

13) In filariasis cause of edema is

a) Lymphatic obstruction b) Malnutrition c) Sodium retention d) Venous obstruction

14) Lepromatous leprosy is characterized by

a) Low bacterial load b) Granulomatous lesions
c) Good immune response d) Negative lepromin test
15) ‘Steatosis’ means abnormal accumulation of

a) Protein within parenchymal cells b) Glycogen within parenchymal cells

c) Water within parenchymal cells d) Fat within parenchymal cells

16) Prussian blue reaction is highly characteristic for demonstration of

a) Glycogen b) Melanin c) Hemosiderin d) Amyloid

17) Events in healing of wound by first intention are all of the following EXCEPT

a) Initial hemorrhage b) Acute inflammatory response

c) Epithelial proliferation d) Wound contraction
18) Frozen section is useful for all of the following EXCEPT

a) Rapid diagnosis of the tissue b) Demonstration of fat

c) Demonstration of enzymes d) For studying detailed morphology of the tumor
19) Which of the following dye is used for Supravital Staining for demonstration of Reticulocytes.

a) Hematoxylin b) Eosin c) Billiant Cresyl Blue d) Prussian Blue

20) Which of the following amino acid replaces Glutamic acid in the 6th position of β Chain
of HemoglobinS
a) Valine b) Histidine c) Leucine d) Lysine
KRISHNA INSTITUTE OF MEDICAL SCIENCES “ DEEMED TO BE UNIVERSITY ”, KARAD.

II MBBS 1st Internal Assessment Examination, May, 2021

PATHOLOGY – Theory Paper

Date: 4-5-2021 Marks : 80

Section B

Q.No.2 Write Large Answer Questions any (3 out of 4) (10 mark x 3 Q.) Marks: 30

1) Define & classify amyloidosis. Describe spleen in Amyloidosis. Write staining characteristics
of amyloid deposits in tissue Section. (1 + 2 + 4 + 3)
2) 27 yrs old female is mother of 3 children, the youngest being one year old. She presented with

weakness, fatigue, tingling numbness in upper extremities and pain & redness of tongue.

O/E pallor + +

1) What is the probable diagnosis? (1)

2) Enumerate hematological investigation to confirm the diangnosis. (3)
3) Describe Peripheral Smear & Bone marrow findings with blood indices of this case. (6)

3) Classify Carcinogens & give one example each. Describe process of Chemical carcinogenesis

with few examples. ( 5 + 5)

4) 12 yrs male presented with history of fall from tree to emergency room. On X ray his left tibia

was fractured.

1) Write steps in healing of a fracture bone with the help of diagrams. (5)
2) Enumerate factors which influence healing of fracture bone. (3)
3) Enlist complications. (2)

Q.No.3 Write Short Answer Questions any ( 9 out of 10) (5 mark x 9 Q.) Marks: 45

1) Define Oedema. Write differences between transudate & exudate with two examples each (1 + 3 + 1)

2) Define Necrosis. Write various types of necrosis & give examples.

3) Define Pathological Calcification. Write differences between Dystrophic and Metastatic

Calcification with two examples.
4) Define Neoplasia. Write differences between benign and malignant neoplasms.
Give two examples each. (1 + 3 + 1)
5) Write in brief on various anticoagulants used in hematology laboratory & their uses.

6) Define infarct. Enumerate types of infarct. Describe gross & microscopic features of infarct

kidney with the help of neat labelled diagram. (1 +1 + 3)

7) 60 yrs Male patient presented with C/o Pain in abdomen, black & tarry stools, weakness &

mild breathlessness on exertion.

On investigation hemoglobin was 8 gm/dl.

1) Write the probable cause & type of anemia. (2)

2) Write investigations to be done in this patient. (3)

8) Define hypertrophy & hyperplasia. Write any two characteristic features with two
examples of each. (2 + 2 + 1)

9) Define & classify Shock. Write morphological features of Shock in following organs
– Lungs & Kidney. (1 + 1 + 3)

10) Write etiology of fatty change of liver. Describe gross & microscopic appearance of fatty liver
with the help of neat labeled diagram. (1 + 4)

Q.No.4 Write Short Answer Question AETCOM Module : Marks: 05

Describe in brief factors which determine decision making capacity and competency

while respecting Autonomy of patient.