Material Safety Data Sheet
N,N-Diisopropylethylamine
MSDS# 01953
Section 1 - Chemical Product and Company Identification
MSDS Name: N,N-Diisopropylethylamine
Catalog AC115220000, AC115220250, AC115221000, AC115225000, AC367840000, AC367840010
Numbers: AC367840010, AC367840250, AC367840500, AC367841000, BP592-500
Synonyms: N-Ethyldiisopropylamine; Hünig's base; EDIPA; Ethyldiisopropylamine; DIPEA.
Acros Organics BVBA
Company Identification: Janssen Pharmaceuticalaan 3a
2440 Geel, Belgium
Acros Organics
Company Identification: (USA) One Reagent Lane
Fair Lawn, NJ 07410
For information in the US, call: 800-ACROS-01
For information in Europe, call: +32 14 57 52 11
Emergency Number, Europe: +32 14 57 52 99
Emergency Number US: 201-796-7100
CHEMTREC Phone Number, US: 800-424-9300
CHEMTREC Phone Number, Europe: 703-527-3887
Section 2 - Composition, Information on Ingredients
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CAS#: 7087-68-5
Chemical Name: N,N-Diisopropylethylamine
%: >98
EINECS#: 230-392-0
----------------------------------------
Hazard Symbols: FC
Risk Phrases: 11 22 34 52/53
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Danger! Flammable liquid and vapor. Causes eye and skin burns. Causes digestive and respiratory tract burns. Target
Organs: Eyes, skin, mucous membranes.
Potential Health Effects
Eye: Causes eye burns.
Skin: Causes skin burns.
Ingestion: Harmful if swallowed. Causes gastrointestinal tract burns.
Inhalation: Causes chemical burns to the respiratory tract.
Chronic: Chronic exposure may cause effects similar to those of acute exposure.
Section 4 - First Aid Measures
In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical aid
Eyes:
immediately.
In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing
Skin:
contaminated clothing and shoes. Get medical aid immediately. Wash clothing before reuse.
If swallowed, do NOT induce vomiting. Get medical aid immediately. If victim is fully conscious, give a
Ingestion:
cupful of water. Never give anything by mouth to an unconscious person.
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Inhalation:
Get medical aid.
Notes to
Treat symptomatically and supportively.
Physician:
Section 5 - Fire Fighting Measures
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved
General or equivalent), and full protective gear. Vapors can travel to a source of ignition and flash back. Containers
Information: may explode in the heat of a fire. Liquid will float and may reignite on the surface of water. Flammable
liquid and vapor. Runoff from fire control or dilution water may cause pollution.
Extinguishing Water may be ineffective. Do NOT use straight streams of water. Use water spray, dry chemical, carbon
Media: dioxide, or appropriate foam.
Autoignition
240 deg C ( 464.00 deg F)
Temperature:
Flash Point: 6 deg C ( 42.80 deg F)
Explosion
0.7% by vol
Limits: Lower:
Explosion
6.3% by vol
Limits: Upper:
NFPA Rating: health: 3; flammability: 3; instability: 0;
Section 6 - Accidental Release Measures
General
Use proper personal protective equipment as indicated in Section 8.
Information:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid
Spills/Leaks: runoff into storm sewers and ditches which lead to waterways. Remove all sources of ignition. Use a
spark-proof tool. Provide ventilation.
Section 7 - Handling and Storage
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Ground and bond
containers when transferring material. Use spark-proof tools and explosion proof equipment. Do not get in eyes,
Handling: on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Do
not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Use only with adequate ventilation. Keep away from heat, sparks and flame. Do not breathe vapor or mist.
Keep away from sources of ignition. Keep container closed when not in use. Store in a tightly closed container.
Storage:
Flammables-area. Store in a cool, well-ventilated area away from incompatible substances.
Section 8 - Exposure Controls, Personal Protection
+-------------------- +------------------- +------------------- +----------------- +
| Chemical Name | ACGIH | NIOSH |OSHA - Final PELs|
|-------------------- |------------------- |------------------- |----------------- |
| N,N-Diisopropylethy|none listed |none listed |none listed |
| lamine | | | |
+-------------------- +------------------- +------------------- +----------------- +
OSHA Vacated PELs: N,N-Diisopropylethylamine: None listed
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use
adequate ventilation to keep airborne concentrations low. Ventilation fans and other electrical service must be non-
sparking and have an explosion-proof design.
Exposure Limits
Personal Protective Equipment
Eyes: Wear chemical splash goggles and face shield.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a
Respirators: NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if
irritation or other symptoms are experienced.
Section 9 - Physical and Chemical Properties
Physical State: Liquid
Color: colorless to light yellow
Odor: amine-like
pH: Not available
Vapor Pressure: 31 mm Hg @ 37.7 deg C
Vapor Density: Not available
Evaporation Rate: Not available
Viscosity: Not available
Boiling Point: 127 deg C @ 760 mmHg ( 260.60F)
Freezing/Melting Point: -50 deg C ( -58.00F)
Decomposition Temperature: Not available
Solubility in water: 3.9 g/l @ 20C
Specific Gravity/Density: 0.760 @ 20C
Molecular Formula: C8H19N
Molecular Weight: 129.24
Section 10 - Stability and Reactivity
Stable under normal temperatures and pressures. Amines absorb carbon dioxide from the
Chemical Stability:
air to form carbamate salts.
Light, ignition sources, moisture, prolonged exposure to air, confined spaces, Avoid
Conditions to Avoid:
aluminum, zinc, copper and their alloys..
Incompatibilities with Other
Strong oxidizing agents, strong acids, aldehydes.
Materials
Hazardous Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide, ammonia, nitriles.
Products
Hazardous Polymerization Will not occur.
Section 11 - Toxicological Information
RTECS#: CAS# 7087-68-5: None listed
LD50/LC50: RTECS: Not available. Other: LD50 (oral, rat): >200-500 mg/kg (Merck SDS dated 14.06.2004).
Carcinogenicity: N,N-Diisopropylethylamine - Not listed as a carcinogen by ACGIH, IARC, NTP, or CA Prop 65.
Section 12 - Ecological Information
Ecotoxicity: Daphnia: Daphnia: 74.3 mg/l; 48H; EC50
Section 13 - Disposal Considerations
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - Transport Information
US DOT
Shipping Name: AMINES, FLAMMABLE, CORROSIVE, N.O.S.
Hazard Class: 3
UN Number: UN2733
Packing Group: II
Canada TDG
Shipping Name: AMINES, CORROSIVE,FLAMMABLE NOS (NN DIISOPROPYLETHYLAMINE)
Hazard Class: 3
UN Number: UN2733
Packing Group: II
Section 15 - Regulatory Information
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: F C
Risk Phrases:
R 11 Highly flammable.
R 22 Harmful if swallowed.
R 34 Causes burns.
R 52/53 Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Phrases:
S 16 Keep away from sources of ignition - No smoking.
S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36/37/39 Wear suitable protective clothing, gloves and eye/face protection.
S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where
possible).
S 61 Avoid release to the environment. Refer to special instructions/safety data sheets.
WGK (Water Danger/Protection)
CAS# 7087-68-5: 2
Canada
CAS# 7087-68-5 is listed on Canada's DSL List
Canadian WHMIS Classifications: B2, E
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations
and the MSDS contains all of the information required by those regulations.
CAS# 7087-68-5 is not listed on Canada's Ingredient Disclosure List.
US Federal
TSCA
CAS# 7087-68-5 is listed on the TSCA
Inventory.
Section 16 - Other Information
MSDS Creation Date: 11/11/1997
Revision #7 Date 7/20/2009
The information above is believed to be accurate and represents the best information currently available
to us. However, we make no warranty of merchantibility or any other warranty, express or implied,
with respect to such information, and we assume no liability resulting from its use. Users should make
their own investigations to determine the suitability of the information for their particular purposes. In no
event shall the company be liable for any claims, losses, or damages of any third party or for lost profits
or any special, indirect, incidental, consequential, or exemplary damages howsoever arising, even if the
company has been advised of the possibility of such damages.
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