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Research Proposal PDF

The document summarizes a study that compares the effects of open and closed kinetic chain exercises on ankle mobility in individuals with right-sided hemiparesis following a stroke. The study involves 30 participants who will be randomly assigned to complete either open or closed kinetic chain exercises 3 times per week for 6 weeks. Outcome measures including range of motion, strength, spasticity, and functional gait will be assessed before, during, and after the intervention period. The researchers hypothesize that closed kinetic chain exercises will have more favorable outcomes on ankle function compared to open kinetic chain exercises.

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0% found this document useful (0 votes)
171 views9 pages

Research Proposal PDF

The document summarizes a study that compares the effects of open and closed kinetic chain exercises on ankle mobility in individuals with right-sided hemiparesis following a stroke. The study involves 30 participants who will be randomly assigned to complete either open or closed kinetic chain exercises 3 times per week for 6 weeks. Outcome measures including range of motion, strength, spasticity, and functional gait will be assessed before, during, and after the intervention period. The researchers hypothesize that closed kinetic chain exercises will have more favorable outcomes on ankle function compared to open kinetic chain exercises.

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7/13/2023

The Effects of Open and Closed Chained


Exercises on Individuals with Hemiparesis
By Delaney Harris & Francis Prins

Key Impairments
● 65 year-old man who had a stroke (1 month ago) resulting in right-
sided hemiparesis
● Decreased range of motion of the right extremities
● Decreased strength (3-/5) across the right leg
● Difficulty ambulating
● Decreased speed, knee hyperextension, toe drag during swing, and
instability during walking
● Uses a quad cane
● Lack of drive and motivation

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Clinical Question
Will a 65-year-old man with right-sided hemiparesis (P) achieve a
meaningful outcome on functional mobility of the ankle joint (O) with open
or closed kinetic chain therapeutic exercises(I/C)?

Introduction
• An ischemic stroke is a disease that is caused by a blockage in an artery
leading to the brain. A hemorrhagic stroke is due to bleeding in the brain
tissue after a blood vessel is ruptured.1
• Hemiparesis is classified by muscular weakness or paralysis on one side
of the body.2
• The severity of hemiparesis from stroke is dependent on harshness of
stroke and the individual’s level of independence or capabilities while
performing functional tasks.
• Distribution of muscle impairment follows the pattern of more distal
muscles usually weaker than the proximal muscles.
• Muscle strength is sometimes regained in a faster manner in lower
extremities than upper extremities.3

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7/13/2023

Purpose
To compare open and closed kinetic chain exercise outcomes on the functional
mobility at the ankle joint.

Subjects
• Stroke patients with hemiparesis
• Recruited from hospitals, assisted living facilities, and outpatient clinics in the
upper peninsula of Michigan
• Inclusion criteria:
– Ages 60 to 80 years of age
– Post-stroke with symptoms of hemiparesis
– Single unilateral stroke
– Minimum to moderate range of motion and strength in joints on affected
side
– Cognitive ability to follow instructions
– Can tolerate testing sessions

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Subjects
Exclusion Criteria:
• Presence neurological disorders not related to stroke
• Acute heart impairments
• Severely affected muscle tone or paresis
• Other orthopedic or musculoskeletal comorbidities that may limit
strength and range of motion in the lower extremity

Study Design
• Experimental Trial
• 2 randomized groups
– Group 1: Open kinetic chain exercises
– Group 2: Closed kinetic chain exercises
• Therapy will be in-clinic, led by two trained physical therapist
• Sample size: 30 participants
• Parameters: 3x a week for 6 weeks
• Each session will last 45 minutes
– 10 minute warm up on NuStep
– 25 minutes for 3 exercises
– 10 minute cooldown for range of motion (ROM) stretching

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7/13/2023

Methodology
• Open kinetic chain exercises: (3 sets, 10 repetitions)
– Calf raises on leg press machine
– Seated resistive band dorsiflexion/ plantarflexion (calf pumps)
– Total Gym squats
• Closed kinetic chain exercises: (3 sets, 10 repetitions)
– Standing calf raises
– Squats
– Forward lunges
• Use weight as tolerated, increase weight every 2 weeks

Methods: Data Collection


Primary outcomes: Valid and reliable clinical scales
• Modified Ashworth Scale (muscle tone and spasticity)4
• ROM (measure dorsiflexion using a goniometer)5
• Functional Gait Assessment (timed 10 meter walk at patients preferred
speed)6
• Manual muscle test (MMT) (ankle dorsiflexion and subtalar inversion
test)7

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7/13/2023

Modified Ashworth Scale

https://www.semanticscholar.org/paper/A-Review-%3A-The-Validity-and-Reliability-of-the-as-a-Bauch-Steinberg/aac2976b83964df77646c38137c6143fcdd658b6

11

Manual Muscle Test Scale


Standard Scale

https://www.prohealthcareproducts.com/blog/manual-muscle-testing-principles-explained/

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Methodology- Data Analysis


• Pre-Test
– Test both groups ROM, muscle tone and spasticity on the Modified
Ashworth Scale, Functional Gait Assessment, and MMT
• Pre-Test II
– Retest after three weeks
• Final Test
– Retest after the six weeks are complete

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Data Analysis
Independent Variable #1: Group 1&2 (open kinetic chain/closed kinetic chain
exercises)
Independent Variable #2: Test time (pre/week 3/week 6)
Dependent Variable: ROM, strength, muscle spasticity/tone, and functional
gait assessment

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Conclusion
• Anticipated study findings:
– It’s believed that closed kinetic chain exercises will have a more
favorable outcome than open kinetic chain exercises
• Limitations:
– Exercises may require guarding
– No minimal detectable change within six weeks
– Large range of deficits present
– Poor intra-rater reliability

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References
1. Paul S, Candelario-Jalil E. Emerging neuroprotective strategies for the
treatment of ischemic stroke: An overview of clinical and preclinical
studies. Exp Neurol. 2021;335:113518.
doi:10.1016/j.expneurol.2020.113518
2. Inatomi Y, Nakajima M, Yonehara T, Ando Y. Ipsilateral hemiparesis in
ischemic stroke patients. Acta Neurol Scand. 2017;136(1):31-40.
doi:10.1111/ane.12690
3. Andrews AW, Bohannon RW. Distribution of muscle strength
impairments following stroke. Clinical Rehabilitation. 2000;14(1):79-87.
doi:10.1191/026921500673950113 (Slide 5)

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References Continued
4. Li F, Wu Y, Li X. Test-retest reliability and inter-rater reliability of the
Modified Tardieu Scale and the Modified Ashworth Scale in hemiplegic
patients with stroke. Eur J Phys Rehabil Med. 2014;50(1):9-15.
5. Konor MM, Morton S, Eckerson JM, Grindstaff TL. Reliability of three
measures of ankle dorsiflexion range of motion. Int J Sports Phys Ther.
2012;7(3):279-287.
6. Middleton A, Fritz SL, Lusardi M. Walking speed: the functional vital
sign. J Aging Phys Act. 2015;23(2):314-322. doi:10.1123/japa.2013-0236
7. Berryman Reece N. Muscle and sensory testing. 4. ed. Elsevier, Inc.;
2020:pages cm.

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