Membrane Potentials
1. Na+-K+-ATPase is an example of a/an:
a) symport
b) uniport
c) biport
d) antiport
e) airport
Answer- D
2. Regarding membrane potential:
a) it is only found in nervous tissue
b) Na+/K+ pump does not contribute to the membrane potential
c) its magnitude does not change from tissue to tissue
d) the membrane potential is negative inside in relation to the outside
e) it is mainly caused by leaking Na+/K+ channels
Answer- D
3. Which of the following has the highest permeability in a resting nerve cell?
a) Na+
b) Cl–
c) I–
d) K+
Answer-D
4. Depolarization is when ___________ ions flow inside the neuron’s membrane.
a) Potassium
b) Sodium
c) Chloride
d) Magnesium
Answer- B
5. A neuron fires when _____________________
a) action potential is achieved
b) apoptosis is induced
c) re-stimulation occurs
d) stimulation ceases
Answer- A
6. Action potential can only flow in the forward direction.
a) True
b) False
Answer- A
7. A typical neuron has a resting membrane potential of about:
(A) +70 mV
(B) +70 V
(C) −70 mV
(D) −70 V
(E) All of the above are observed at rest
Correct answer: C
8. Which of the following is (are) directly responsible for the generation of the resting membrane
potential?
(A) Ionic gradients across the plasma membrane
(B) Permeability of the plasma membrane to various ions
(C) The Na+/K+ ATPase
(D) A and B only
(E) A, B, and C
Correct answer: D
9. The Na+/K+ ATPase is directly responsible for the establishment of the membrane potential.
True
False
Correct answer: False
10. By maintaining the Na+ and K+ concentration gradients, the Na+/K+ ATPase is responsible for
maintaining the membrane potential.
True
False
Correct answer: True
11. The following ion(s) is(are) the major contributor(s) to establishing the value of the resting
membrane potential in most cells.
(A) Na+
(B) K+
(C) Ca2+
(D) H+
(E) Cl−
Correct answer: A, B, and E
12. Which type of K+ channels share in resting membrane potential generation?
a. Leakage channel
b. Voltage gated channel
c. Calcium gated channels
d. Non selective ion channel
Answer- A
13. Which part of the neuron initiates the action potential?
a. Dendrites
b. Axon hillock
c. Cell body
d. Axon terminal
Answer- B
14. Resting membrane potential is created by all of the following membrane characteristics EXCEPT
a. High permeability to K+
b. Low permeability to Na+
c. High permeability to proteins
d. Opening of voltage gated sodium channels
Answer- C, D
15. In a cell membrane with resting membrane potential -60. If this potential becomes -90 there will be
a. Depolarization of 30 mv amplitude
b. Hyperpolarization with 30 mv amplitude
c. Local excitatory state
d. Generation of action potential with subthreshold stimulus
Answer- B
16. What is the main cation present intracellulary
a. K+
b. Na+
d. Ca++
d. Mg++
Answer- A