TRANSCRIPTION, TRANSLATION AND MUTATION ACTIVITY
For each example:
a. Fill in the complimentary DNA strand
b. Fill in the correct mRNA bases by transcribing the bottom DNA code
c. Fill in the correct tRNA bases
d. Translate the mRNA codons to find the correct amino acids
Example 1. Assume TAC-CGT-AAT-ACT sequence in the DNA template strand
DNA Coding
Strand
DNA Template
Strand
mRNA
(codon strand)
tRNA
(anticodon codon)
Amino Acids
Example 2. The 7th base becomes G replacing A? (TAC-CGT-GAT-ACT)
DNA Coding
Strand
DNA Template
Strand
mRNA
tRNA
Amino Acids
Example 3. The 8th base becomes T replacing A? (TAC-CGT-ATT-ACT)
DNA Coding
Strand
DNA Template
Strand
mRNA
tRNA
Amino Acids
Example 4. The 7th base becomes C replacing A? (TAC-CGT-CAT-ACT)
DNA Coding
Strand
DNA Template
Strand
mRNA
tRNA
Amino Acids
Example 5. What if A is added in the 4th position? (TAC-ACG-TAA-TAC)
DNA Coding
Strand
DNA Template
Strand
mRNA
tRNA
Amino Acids
Example 6. How about removing G in the 5th position? (TAC-CTA-ATA-CTC)
DNA Coding
Strand
DNA Template
Strand
mRNA
tRNA
Amino Acids
What do you notice? What do you wonder?
-dmgermino’2023
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