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BP401TT

This document outlines the scope, objectives, teaching scheme, and topics for the subject Pharmaceutical Organic Chemistry III. The subject imparts knowledge on stereo-chemical aspects of organic compounds, important organic reactions, and the chemistry of hetero cyclic compounds. It emphasizes the medicinal and other uses of organic compounds. The objectives are to understand organic compound preparation and properties, explain stereo chemical aspects and reactions, and know medicinal and other applications. Topics include stereo isomerism, geometrical isomerism, heterocyclic compounds like pyrrole and furan, and important organic reactions.

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Radhika Jasani
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41 views2 pages

BP401TT

This document outlines the scope, objectives, teaching scheme, and topics for the subject Pharmaceutical Organic Chemistry III. The subject imparts knowledge on stereo-chemical aspects of organic compounds, important organic reactions, and the chemistry of hetero cyclic compounds. It emphasizes the medicinal and other uses of organic compounds. The objectives are to understand organic compound preparation and properties, explain stereo chemical aspects and reactions, and know medicinal and other applications. Topics include stereo isomerism, geometrical isomerism, heterocyclic compounds like pyrrole and furan, and important organic reactions.

Uploaded by

Radhika Jasani
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as PDF, TXT or read online on Scribd
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GUJARAT TECHNOLOGICAL UNIVERSITY

Bachelor of Pharmacy
Subject Code: BP401TT
SEMESTER: IV
Subject Name: Pharmaceutical Organic Chemistry III

Scope: This subject imparts knowledge on stereo-chemical aspects of organic compounds and organic
reactions, important named reactions, chemistry of important hetero cyclic compounds. It also
emphasizes on medicinal and other uses of organic compounds.

Objectives: Upon completion of the course the student shall be able to


1. understand the methods of preparation and properties of organic compounds
2. explain the stereo chemical aspects of organic compounds and stereo chemical reactions
3. know the medicinal uses and other applications of organic compounds

Teaching scheme and examination scheme:

Teaching Scheme Evaluation Scheme


Theory Tutorial Practical Total Theory Practical
External Internal External Internal
3 1 0 4 80 20 0 0

Sr No Topics %
weightage
1. Stereo isomerism 10
Optical isomerism –
Optical activity, enantiomerism, diastereoisomerism, meso compounds
Elements of symmetry, chiral and achiral molecules
DL system of nomenclature of optical isomers, sequence rules, RS system of
nomenclature of optical isomers
Reactions of chiral molecules
Racemic modification and resolution of racemic mixture.
Asymmetric synthesis: partial and absolute
2. Geometrical isomerism 10
Nomenclature of geometrical isomers (Cis Trans, EZ, Syn Anti systems)
Methods of determination of configuration of geometrical isomers.
Conformational isomerism in Ethane, n-Butane and Cyclohexane.
Stereo isomerism in biphenyl compounds (Atropisomerism) and conditions for
optical activity.
Stereospecific and stereoselective reactions
3. Heterocyclic compounds: 10
Nomenclature and classification
Synthesis, reactions and medicinal uses of following compounds/derivatives
Pyrrole, Furan, and Thiophene
Relative aromaticity and reactivity of Pyrrole, Furan and Thiophene
Synthesis, reactions and medicinal uses of following compounds/derivatives 8
4. Pyrazole, Imidazole, Oxazole and Thiazole.
Pyridine, Quinoline, Isoquinoline, Acridine and Indole. Basicity of pyridine
Synthesis and medicinal uses of Pyrimidine, Purine, azepines and their
derivatives
5. Reactions of synthetic importance 7
Metal hydride reduction (NaBH4 and LiAlH4), Clemmensen reduction, Birch
reduction, Wolff Kishner reduction.
Oppenauer-oxidation and Dakin reaction.
Beckmanns rearrangement and Schmidt rearrangement.

Page 1 of 2
w.e.f. AY 2017-18
GUJARAT TECHNOLOGICAL UNIVERSITY
Bachelor of Pharmacy
Subject Code: BP401TT
Claisen-Schmidt condensation

Recommended Books (Latest Editions)

1. Organic chemistry by I.L. Finar, Volume-I & II.


2. A text book of organic chemistry – Arun Bahl, B.S. Bahl
3. Heterocyclic Chemistry by Raj K. Bansal
4. Organic Chemistry byMorrison and Boyd
5. Heterocyclic Chemistry by T.L. Gilchrist

Page 2 of 2
w.e.f. AY 2017-18

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