K.G.
Mittal Ayurved College
By Saketkumar Srivastava,2nd BAMS,36
DEPARTMENT OF DRAVYAGUNA
Under Guidance of Vd.Balaji Sawant(HOD),
Vd.Janhavi Alwe(Asso.Prof.),
Vd.Shraddha Chaudhari (Asst.Prof)
Research Updates on
Ativisha,Sairayak,Shallaki,Sarpagandha,Shalmali(Mocharasa),Shankhapushpi,Shigru
1.Recent Research on Ativisha
• Two new diterpenoid alkaloids, heterophyllinine-A (1) and heterophyllinine-B (2), along with two known alkaloids
dihydroatisine (3) and lycoctonine (4) were isolated from the roots of Aconitum heterophyllum Wall. Nisar M, Ahmad
M, Wadood N, Lodhi MA, Shaheen F, Choudhary MI. New diterpenoid alkaloids from Aconitum heterophyllum Wall:
Selective butyrylcholinestrase inhibitors. J Enzyme Inhib Med Chem. 2009 Feb; 24 (1): 47-51.
• Two new aconitine-type norditerpenoid alkaloids 6- dehydroacetylsepaconitine (1) and 13- hydroxy- appaconitine (2)
along with three known norditerpenoid alkaloids lycoctonine, delphatine and lappaconitine were isolated from the
roots of the Aconitum heterophylum Wall. These compounds exhibited significant antibacterial activity. Ahmad M,
Ahmad W, Ahmad M, Zeeshan M, Obaidullah, Shaheen F. Norditerpenoid alkaloids from the roots of Aconitum
heterophylum Wall with antibacterial activity. J Enzyme Inhib Med Chem. 2008 Dec; 23 (6): 1018-22.
• The Immunobiological activity was investigated of certain medicinal plants widely used in the Ayurvedic and Unani
systems of medicine for the treatment of chronic infections and immunological disorders. The effect of an ethanolic
extract of each drug was studied on delayed-type hypersensitivity, humoral responses to sheep red blood cells, skin
allograft rejection, and phagocytic activity of the reticuloendothelial system in mice. Aconitum heterophyllum
appeared to stimulate phagocytic function while inhibiting the humoral component of the immune system. Atal CK,
Sharma ML, Kaul A, Khajuria A. Immunomodulating agents of plant origin.; Preliminary screening. J. Ethnopharmacol.
1986 Nov; 18 (2): 133-41.
• In the absence of a desired first choice medicinal herb, classical Ayurveda recommends the use of a functionally
similar substitute. Post 16th century Ayurvedic texts and lexicons give specific examples of possible substitutes. Here
we report a preliminary study of one such Ayurvedic substitution pair: Musta (Cyprus rotundus L., Cyperaceae), a
common weed, for the rare Himalayan species, Ativisha (Aconitum heterophyllum Wall. Ex Royle; Ranunculaceae).
Observations indicate that Ayurveda may attach more importance to the pharmacological properties of raw drugs
than to their botanical classification. Venkatasubramanian P, Kumar SK, Nair VS. Cyperus rotundus, a substitute for
Aconitum heterophyllum: Studies on the Ayurvedic concept of Abhava Pratinidhi Dravya (Drug substitution). J
Ayurveda into. Med.2010 Jan; 1 (1): 33-9.
• Anti-inflammatory
• Anti-bacterial
• Immune-modulatory
• Antihyperlipidemic
• Carminative
2.Recent Research on Sairayak
• Tundikeri is a Kanthagata Vyadhi which is more Predominantly seen in children with no significant relation to Sex,
religion and geographical distribution. Its signs and Symptoms correlates with Tonsillitis in contemporary Medicine. If
the condition is left untreated it may lead to Several serious health hazards. Saireyaka provides good relief In the
symptoms of Tundikeri effectively.EFFECT OF SAIREYAKA (BARLERIA PRIONITIS) IN TUNDIKERI (TONSILLITIS): A
CLINICAL STUDY by Jindal Radha,Jindal Dilbag , U Shailaja, Powar Sudhakar
• Anti-Diabetic Activity:Geetha M, Wahi A. Antidiabetic activity of Barleria prionitis Linn. Journal of Natural Remedies.
2001;1(1):64-6.
• Hepato-protective Activity:Sharmin T, Ahmed S, Islam F. Biological activities of Barleria Prionitis . International
Journal of Research in Pharmacology and Pharmacotherapeutics. 2013; 2(2):367-71.
• Wound healing activity :Sharmin T, Ahmed S, Islam F. Biological activities of Barleria cristata. International Journal of
Research in Pharmacology and Pharmacotherapeutics. 2013; 2(2):367-71.
• Anti infertility activity:Gupta R.S.,P.Kumar,V.P.Dixit,M.P.Dobhal 2000,Antiinfertility studies of the root extract of the
Barleria prionitis Linn. In Male albino rats with special reference to testicular cell population
Dynamics,J.Ethnopharmacol 70-111-117
• Anti-bacterial Activity: Sulthana BS. Investigation of anti-bacterial activity of different extracts of Barleria cristata
leaves. International Journal of Health Sciences and Resarch. 2017; 7(9):90-5.
3.Recent Research on Shallaki
• Clinical evaluation of Boswellia serrata (Shallaki) resin in the management of Sandhivata (osteoarthritis)by P K Gupta
et al. Ayu. 2011 Oct.
• Efficacy of Guggulu and Shallaki based Ksharasutra with Triphala Guggulu orally in the management of Bhagandara
w.s.r. to fistula-in-ano: A open labelled randomized comparative clinical study by Aditya Nema et al. Ayu. 2020 Oct-
Dec.
4.Recent Research on Sarpagandha
• Effect of Brahmi vati and Sarpagandha Ghana vati in management of essential hypertension – A randomized, double
blind, clinical study by Dhanpat Mishra, Basavaraj R. Tubaki
• The role of psychic factors in pathogenesis of essential hypertension and its management by Shirodhara and
Sarpagandha Vati by Sarpagandha Vati by Kundu, Chittaranjan; Shukla, V. D.; Santwani, M. A. M.D. Bhatt, N. N.
5.Recent Research on Shalmali
• TO EVALUATE THE CLINICAL EFFICACY OF SHALMALI MOOLA (BOMBAX CEIBA LINN.) AS VRISHYA ON SEMINAL
PARAMETER”. A CASE STUDY Dr. Raj Kumar, Dr. Satender Khatri, Dr. Rajiv Bansal, Dr. Manoj Kumar
• Evaluation of In-Vitro Studies of the Shalmali Extract on Human Endometrial Stromal Cells by Anandhan P,Muttevi
Hayagreva Kumar, Saad H Elshafey,3 Janaki C S,4 Sumathi Jones,corresponding author5 Dhastagir Sheriff,6
Akshara Pramod Roy, Gopi Ayyaswamy, Balaji TK, and Prabhu K
• ROLE OF SHALMALIGHRITA IN THE MANAGEMENT OF ASRIGDARA VIS-À-VIS ABNORMAL UTERINE BLEEDING (AUB):
A REVIEW by Vijendra Kumar Gupta Shilpy
6.Recent Research on Shankhapushpi
• Comparative pharmacognostical investigation on four ethanobotanicals traditionally used as Shankhpushpi in India Neeraj K. Sethiya, Ashish Trivedi,
Mayur B. Patel, and S. H. Mishra
• AYURVEDIC MEDICINAL IMPORTANCE OF SHANKHPUSHPI (CONVOLVULUS PLURICAULIS): POTENTAIL COGNITION
BOOSTING HERB by Shifali Thakur, Hemlata kaurav
7.Recent Research on Shigru
• Antihypertensive
• Diuretic
• Cholesterol lowering activities, antispasmodic, antiulcer
• Hepatoprotective activities, antibacterial and antifungal activities,
• Antitumor and anticancer activities,
• Aqueous Leaf extracts regulate thyroid hormone and can be used to Treat hyperthyroidism and exhibit an antioxidant
effect.
• It is used as a prophylactic or therapeutic anti-HSV (Herpes Simplex virus type 1) medicine and may be effective
against The acyclovir-resistant variant patients.
• It protects the Human skin from environmental influences and combats Premature skin aging. It is a miraculous tree
widely used As a edible one and used abundantly in the preparation of Various medicines.
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