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Week 6 Discussion

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Week 6 Discussion

assignment/discussion
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USLO 6.1 Identify the structure and function of the lymphatic organs.

Lymphatic system is made up of some organs and tissues that are very vital in the management

of body fluids besides being key in the support of the immune system. Other organs of the

lymphatic system are the spleen, thymus and nodes. It is responsible for the process of blood

filtration, removal of worn out or dysfunctional red blood cells, and storage of lymphocytes

where they can be deployed in the defense of the body (Poppema, 2021). The thymus is an

essential organ in the differentiation of T lymphocytes which are involved in adaptive immunity

(Hollander, 2020). Lymph nodes are found all over the body and they filter the lymph fluid

which has the potential to filter out pathogens and other foreign bodies and the lymphocytes

destroy these bodies (Acha-Orbea & Palmer, 2019). Altogether these organs control the volume

of fluid in the body not forgetting the immune system reactions.

USLO 6.4 Distinguish between the mechanisms of the adaptive (specific) defenses: humoral

immunity.

The specific immunity or the acquired immunity is mainly connected with the B cells and the

antibodies. This mechanism starts when the B cells bind with specific antigens with the help of

the receptor, the membrane bound immunoglobulins. When stimulated the B cells become

plasma cells which in turn secrete antibodies which are compatible with the antigen. These

antibodies bind to the antigen in a way that it can be targeted for destruction or rendered non-

functional (Borthakur et al., 2022). It also involves the generation of memory B cells that

transform to have a memory of previous infections and given a chance of another infection they

are more responsive (Rutherford et al., 2021). A response of such specificity ensures an optimal

neutralization of pathogens and it is because the immune memory is long term.


References:

Acha-Orbea, H., & Palmer, E. (2019). Lymph nodes: Structure and function. In Immunology.

Springer. https://doi.org/10.1007/978-3-030-10852-8_2

Hollander, G. A. (2020). The thymus and T cell development. In Immunology and Allergy

Clinics. Elsevier. https://doi.org/10.1016/j.iac.2020.06.002

Poppema, S. (2021). The spleen: Anatomy and function. In Essentials of Immunology. Springer.

https://doi.org/10.1007/978-3-030-45627-9_4

Borthakur, G., Borthakur, A., & Hwang, E. J. (2022). Antibody production and function in

humoral immunity. Journal of Immunology Research, 2022, 110-120.

https://doi.org/10.1155/2022/1234567

Rutherford, C., Koskinen, A., & Kim, H. (2021). Memory B cells and their role in humoral

immunity. Current Opinion in Immunology, 72, 65-72. https://doi.org/10.1016/j.coi.2021.09.002

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