COMPREHENSIVE RXFILES ABBREVIATION LIST:

: agonist : Sail Dialysis coverage SK ARR: absolute risk reduction CDN: Canadian DI: drug interaction FBG: fasting blood glucose HE: hepatic encephalopathy
Θ: inhibitor or antagonist ART: antiretroviral therapy CDR: Common Drug Review Dig: digoxin FDA: approved Food & Drug Admin. Hep: hepatitis
1: primary endpoint ARV: antiretroviral CEPH: cephalosporins DIRA: Deficiency of the interleukin- Fe++: iron HF: heart failure
2: secondary endpoint AS: ankylosing spondylitis CER: control group event rate 1–receptor antagonist FeSO4: ferrous sulfate HFI: hormone free interval
5-ASA: 5-aminosalicyclic acid ASA: acetylsalicylic acid CgA: chromogranin DIS: disadvantage FEV1: forced expiratory volume in 1 second HFTD: heart failure target dose
(mesalamine) ASCVD: atherosclerotic CGI: Clinical Global Impression scale DKA: diabetic ketoacidosis FGM: flash glucose monitoring HF-pEF/HF-rEF: heart failure
5HT: serotonin cardiovascular disease CGM: continuous glucose monitoring DM: diabetes mellitus FGA: First-generation antipsychotic preserved/reduced ejection
6MP: mercaptopurine AST: aspartate aminotransferase CHC: combined hormonal contraceptive DMPA: depot medroxyprogesterone FGS: Ferriman-Gallwey Score fraction
A or alternate site testing CHD: coronary heart disease acetate FMT: fecal microbiota transplantation Hgb: haemoglobin
A1c: glycosylated hemoglobin ASx: asymptomatic ChewT: chewable tablet DO : detrusor muscle overactivity FNAB: fine needle aspiration biopsy HHF: hospitalizations for heart failure
ATA: American Thyroid Association CHO: carbohydrate DOAC : direct oral anticoagulant FQ: fluoroquinolone HIT: heparin-induced
AAA: abdominal aortic aneurysm AV: atrioventricular
AAP: American Academy Pediatrics chol: cholesterol DOC: drug of choice FSH: follicle stimulating hormone thrombocytopenia
AVR: atrial valve repair CI: confidence interval DPP4i: dipeptidyl peptidase-4 inhibitor FT: family therapy HIV: human immunodeficiency virus
Ab: antibody AZA: azathioprine
Abd: abdominal CI: contraindicated DRESS : drug rash with eosinophilia FT4: free thyroxine HMG: HMG-CoA reductase= statin
B CIC: chronic idiopathic constipation and systemic symptoms FTE: full time equivalent HPA: hypothalamic pituitary adrenal
ABX: antibiotic
AC: allocation concealment B2: beta-2 receptor agonist CIR: controlled ileal release DRI: direct renin inhibitor FVC: forced vital capacity axis
ac: before meals BB: beta-blocker CIS: clinically isolated syndrome DRSP: drug resistant Streptococcus Fx: function HPV: human papillomavirus
ACEi: angiotensin converting enzyme Θ BBB: blood brain barrier CK: creatine kinase pneumonia G HQ: High quality
ACh: anticholinergic BBB: bundle branch block CKD: chronic kidney disease DS: double strength G6PD: glucose-6-phosphate HQC: Health Quality Council
BCRP: breast cancer resistance protien CNCP: chronic non-cancer pain DU: duodenal ulcer HR: heart rate or hazard ratio
AChEi: acetylcholinesterase inhibitor dehydrogenase
ACR: albumin:creatinine ratio BF: breast feeding CNI: calcineurin inhibitors Dur: duration g: generic/biosimilar hr: hour
ACR: American College of Rheumatology BG: blood glucose CNS: central nervous system DVP: divalproex g: grams HRQL: health-related quality of life
ACS: acute coronary syndrome BID: twice daily COC: combined oral contraceptive DVT: deep vein thrombosis GA: gestational age HRS: Heart Rhythm Society
ADA: American Diabetes Association BIS: bismuth COMPUS: Canadian Optimal dx: disease/diagnosis GAD: generalized anxiety disorder HRT: Hormone Replacement
BMD: bone mineral density Medication Prescribing and DXA: dual energy x-ray Therapy
ADAb: Antidrug antibodies GAS: Group A Streptococci
BMI: body mass index Utilization Service (Now CADTH) absorptiometry HS: bedtime
ADAS-cog: cognitive section of the GC: glucocorticoid
70 point Alzheimer’s Disease BMR: basal metabolic rate COPD: chronic obstructive dysfx: dysfunction GCA: Giant cell arteritis HSA: human serum albumin
Assessment Scale BMS: bare metal stent pulmonary disease E GERD: gastroesophageal reflux HSCT: hematopoietic stem cell
ADHD: attention deficit hyperactivity BNP: brain natriuretic peptide COX: cyclooxygenase enzyme E2: estradiol 17 disease transplantation
disorder BP: blood pressure COXIB: selective cyclooxygenase EAP: Exceptional Access Program GestHTN: gestational hypertension Ht: height
BPH: benign prostatic hyperplasia 2 inhibitor HTN: hypertension
ADJ: adjunctive EBM: evidence based medicine GFR: glomerular filtration rate
BPO: benzoyl peroxide Cp: plasma level HypoG: hypoglycemia
ADR: adverse drug reaction EBV: Epstein-Barr Virus GH: growth hormone
ADT: androgen deprivation therapy BUN: blood urea nitrogen CPA: cyproterone acetate EC: emergency contraception GI: gastrointestinal hx: history
ADV: advantage Bup/nx: buprenorphine/naloxone CPK: creatine phosphokinase EC: enteric coated GIO: glucocorticoid induced I
AE: adverse events BZ or BZD: benzodiazepine CPS: Compendium of ECG: electrocardiogram osteoporosis I: iodine
AECOPD: acute exacerbation of C Pharmaceuticals & Specialties ECT: electroconvulsive therapy GLP1: glucagon-like peptide-1 I-131: radioactive iodine
COPD c: cartridge CrCl: creatinine clearance ED: erectile dysfunction receptor agonist I-131U: radioactive iodine uptake
AF/AFib: atrial fibrillation C. diff: Clostridium difficile CR/MQ: conditional recommendation EDDP: 2-ehtylidine-1,5-dimethyl-3,3- GnRH: gonadotropin releasing IA: intra-articular
AFL: atrial flutter C&S: culture & sensitivity /moderate quality evidence diphenylpyrrolidine hormone IBD: inflammatory bowel disease
AHA: American Heart Association CA: cancer CRF: chronic renal failure EDS: exception drug status GPA: granulomatosis with polyangitis ICC: intermittent clean
AI: aromatase inhibitor Ca++: calcium crm: cream EE: ethinyl estradiol grp: group catheterization
Al+++: aluminum CaAcetate: calcium acetate CRP: C-reactive protein EER: experimental event rate GT: genotype ICD: implantable cardioverter-
Alb: albumin CABG: coronary artery bypass graft CRT: cardiac resynchronization therapy EF: ejection fraction GTC: generalized tonic clonic defibrillator
AlOH: aluminum hydroxide CAC: coronary artery calcification score CSII: continuous subcutaneous eGFR: estimated glomerular GU: gastric ulcer ICH: intracranial hemorrhage
ALT: alanine aminotransferase CaCarb: calcium carbonate insulin infusion filtration rate H ICS: inhaled cortiocosteroid
Alt: alternate CAD: coronary artery disease CTZ: chemoreceptor trigger zone EIB: exercise-induced bronchospasm ICU: Intensive care unit
CADTH: Canadian Agency for Drugs H. pylori: Helicobacter pylori
AKI: acute kidney injury CV: cardiovascular EN: each nostril H2O: water IDA: iron deficiency anemia
am: morning in Technology & Health CVA: cerebrovascular accident ENRD: endoscopic negative reflux dx IDU: injection drug use
CAInh: carbonic anhydrase inhibitor H2RAs: histamine 2 receptor
AMG: aminoglycoside CVD: cardiovascular disease EPT: expedited partner therapy antagonists IFG: impaired fasting glucose
AMIO: amiodarone CA-MRSA: community associated CXR: chest x-ray EPS: extrapyramidal symptoms IFNB: interferon beta
methicillin resistant HA: headache
Amp: ampule CYP 450: cytochrome p 450 enzyme ER: emergency room HAART: highly active antiretroviral tx IFR: infrared data transfer
ANC: absolute neutrophil count Staphylococcus aureus CYP: cytochrome ER: event rate or extended release Ig: immunoglobulin
CAP: community acquired pneumonia HAV: hepatitis A virus
AnO: anorgasmia D ESA: erythropoiesis stimulating agent HBeAg: Hep B “e” antigen IGT: impaired glucose tolerance
cap: capsule IHPS: infantile hypertrophic pyloric
Anti-TPO: antithyroid peroxidise CBC: complete blood count d: day ESC: European Society of Cardiology HBR: high bleed risk
antibody CBD: cannabidiol D: diarrhea ESR: erythrocyte sedimentation rate HBsAg: Hep B “surface” antigen stenosis
AOM: acute otitis media CBT: cognitive behavioural therapy DC: Diabetes Canada esp: especially HBV: hepatitis B virus iL: interleukin
AP-A: atypical antipsychotics CBTi: cognitive behavioral tx insomnia D/C: discontinue(d) ESRD: end stage renal disease HC: Health Canada or IM: intramuscular
AP-C: conventional antipsychotic CBZ: carbamazepine D1,2,3,4: dopamine receptor types ET: essential tremor Hypertension Canada Inf: infection
ApoA1: apolipoprotein A1 CC: citalopram Dopa: dopamine EtOH: alcohol HCC: hepatocellular carcinoma Inj: injection
ApoB: apolipoprotein B cc: with food DA: dopamine agonist EU: European Union HCM: hypercalcemia of malignancy I INR: international normalized ratio
aPTT: activated partial CCB: calcium channel blocker DAPT: dual antiplatelet therapy F Hct: hematocrit Ins: insulin
thromboplastin time CCI: cell cycle inhibitor DBP: diastolic blood pressure F: bioavailability HCTZ: hydrochlorothiazide INSTI: Integrase Strand Transfer Θ
ARB: angiotensin II receptor blocker CCS SAF: Canadian Cardiovascular DDVAP: desmopressin f/u: follow-up HCV: hepatitis C virus IOP: intraocular pressure
ARDS: acute respiratory distress Society Severity in AF DE: delayed or no ejaculation FABA: fast-acting beta-2 agonist HCW: Health care worker iPTH: intact parathyroid hormone
syndrome CD: controlled delivery DERM: dermatologic FAP: familial adenomatous polyposis HD: hemodialysis IRIS: immune reconstitution
ARI: absolute risk increase CD: Crohn’s Disease DES: drug eluting stent FAQ: Functional Activities HD-ESRD: hemodialysis end-stage inflammatory syndrome
ARNI: angiotensin receptor- CDAD: Clostridioides difficle- DHP: dihydropyridine Questionnaire renal disease IS: immunosuppressants
neprilysin inhibitor associated diarrhea DHT: dihydrotestosterone HDL: high density lipoprotein ISA: intrinsic sympathomimetic
FAS: fetal alcohol syndrome activity
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ISH: isolated systolic hypertension Mg++: magnesium OATP: organic anion-transporting PPBG: postprandial (2hr) blood SD: sexual dysfunction (general) TG: triglycerides
IPT: interpersonal therapy mg: milligrams polypeptide glucose SGA: Second-generation antipsychotic THA: total hip arthroplasty
ITT: intention to treat MHV: mechanical heart valve OBMT: omeprazole, bismuth, PP: plaque psoriasis or per protocol SGLT2i: sodium-glucose THC: delta-9-tetrahydrocannabinol
IU: international units MI: myocardial infarction metronidazole, tetracycline PPI: proton-pump inhibitor co-transporter-2 inhibitor TIA: transient ischemic attack
IUD: intrauterine device MINF: nonfatal MI OCD: obsessive compulsive disorder Pr: prescription SHBG: sex hormone binding globulin TIBC: total iron binding capacity
IV: intravenous min(s): minute(s) OC: oral contraceptives pr: per rectum SIADH: syndrome of inappropriate TID: three times daily
IVDU: intravenous drug user mL: milliliter OD: daily PrEP: pre-exposure prophylaxis antidiuretic hormone secretion TKA: total knee arthroplasty
IVIg: IV immunoglobulin MMR: measles, mumps, rubella ODT: orally disintegrating tablet Pria: priapism SJS: Stevens-Johnson Syndrome TKI: tyrosine kinase inhibitor
MMSE: Mini-mental state PRN: as needed SJW: St. John’s Wort TMP/SMX: cotrimoxazole or
J examination (Scale 0-30) OGTT: oral glucose tolerance test trimethoprim/sulfamethoxazole
ProD: prodrug SK: Saskatchewan
JIA: juvenile idiopathic arthritis MOA: method of action OL: open label PRSP: penicillin resistant SL: sublingual TMS: transcranial magnetic
JRA: juvenile rheumatoid arthritis mo(s): month(s) ONJ: osteonecrosis of the jaw Streptococcus pneumoniae SLE: systemic lupus erythematosus stimulation
JVP: jugular venous pressure MPH: methylphenidate Ons: onset PsA: psoriatic arthritis SMBG: self monitor blood glucose TN: trigeminal neuralgia
K MQ: Moderate quality OP: osteoporosis Psyc: schizophrenia SNAP-IV: revised Swanson, Nolan & TNF: tumor necrosis factor
K+: potassium MR: modified release OR: odds ratio Pt(s): patient(s) Pelham Questionnaire TOD: target organ damage
L MRA: mineralcorticoid receptor OS: oral solution PTCS: pseudotumor cerebri syndrome SNRI: serotonin norepinephrine TPMT: thiopurine S-methyltransferase
LA: long acting antagonist OSA: obstructive sleep apnea PTSD: post traumatic stress disorder reuptake inhibitor TPO: thyroid peroxidase
LABA/ICS: LABA combination with an MRC: Medical Research Council OTC: over the counter PTLD: post-transplant SOGC: Society of Obs & Gyne of CDN tpt: transplant
inhaled corticosteroid dyspnea scale OUD: opioid use disorder lymphoproliferative disorders soln: solution TRABs: thyroid receptor antibodies
MS: multiple sclerosis P PUD: peptic ulcer disease SOT: solid organ transplant TSAT: transferrin saturation
LABA: long-acting beta-2 agonist MSM: men who have sex with men TSH: thyroid stimulating hormone
p: pen or p-value pv: per vagina SPDP: Sask. Prescription Drug Plan
LA-DHP: long-acting dihydropyrodine MSU: midstream urine PVD: peripheral vascular disease SPMS: secondary progressive Tsp: teaspoonsful (~5mL)
LAIA: long-acting inj/insulin analogue P: psoriasis
MTCT: mother-to-child-transmission P-gp: permeability glycoprotein PVR: post void residual multiple sclerosis TT: triple therapy
LAMA: long-acting muscarinic MTX: methotrexate PWID: people who inject drugs SR/HQ: strong recommendation/ TTP: thrombotic thrombocytopenic
PA: prolonged action
antagonist MVP: mitral valve prolapse PABA: para-aminobenzoic acid Px: procedure high quality evidence purpura
LBW: lean body weight MVR: mitral valve repair PAD: peripheral arterial disease Q SR: sustained release or tx: treatment
LD: loading dose MVS: mitral valve strands PAH: pulmonary arterial hypertension QALY: quality adjusted life year systematic review or TZD: thiazolidinedione (glitazones)
LDL: low density lipoprotein N Pat: patch QE: quality of evidence strength recommendation U
LDUH: low dose unfractionated N: nausea pc: after meals QID: four times daily SRL: sirolimus U/S: ultrasound
heparin n: number PCC: prothrombin complex QOL: quality of life Ss: steady state UA: unstable angina
Levo: levonorgestrel N/A: not applicable concentrate QTc: corrected QT interval SSRI: selective serotonin reuptake UBT: urea breath test
LFT: liver function test N/V: nausea/vomiting PCI: percutaneous coronary inhibitor(s) UC: ulcerative colitis
R SSS: sick sinus syndrome
LGS: Lennox-Gastaut Syndrome N/V/D: nausea/vomiting/diarrhea intervention UDS: urine drug screen
Na+: sodium PCOS: polycystic ovary syndrome R/O: rule out SSZ: sulfasalazine UGIB: upper gastrointestinal bleed
LH: luteinizing hormone RA: rheumatoid arthritis
Li+: lithium NAb: neutralizing antibody PCP/PJP: Pneumocystis ST: stent thrombosis UI: urinary incontinence
NaCl: sodium chloride RAIA: rapid-acting insulin analogue STI: sexually transmitted infection UKPDS: United Kingdom prospective
Lib: libido jiroveci/carinii pneumonia RBC: red blood cells
LMWH: low molecular weight NAION: nonarteric ischemic optic PCR: polymerase chain reaction SU: sulfonylurea diabetes study
neuropathy PD: panic disorder RCT: randomized controlled trial SUA: serum uric acids UL: upper limit
heparin RDW: red cell distribution width subcut: subcutaneous
NE: norepinephrine PD: Parkinson’s disease UPDRS: Unified Parkinson’s Disease
LOC: loss of consciousness Rec: recommended SUD: substance use disorder Rating Scale
NG: nasogastric PD-CKD: peritoneal dialysis-chronic
LT3: liothyronine NICE: National Institute for Health & reg: regular SUI: stress urinary incontinence URTI: upper respiratory tract
kidney disease REMS: risk evaluation mitigation
LT4: levothyroxine Clinical Excellence PDA: panic disorder with Sul: sulphur infection
LTC: long term care NIHB: non-insured health benefits agoraphobia strategy Supp: suppository USA: approved by United States
LTRA: leukotriene receptor antagonist NMS: neuroleptic malignant PDE5i: phosphodiesterase-5 inhibitor RF: risk factor or rheumatoid factor Susp: suspension UTI: urinary tract infection
LV: left ventricular syndrome rhTSH: recombinant TSH SVT: supraventricular tachycardia V
PDN: painful diabetic neuropathy RIMA: reversible inhibitor MAO-A
LVAD: left ventricular assist device NNH: number needed to harm PE: pulmonary embolism sx: symptoms or syndrome v: vial
LVCVI: left ventricular cavity volume NNRTI: non-nucleoside reverse PEj: premature ejaculation RLS: restless leg syndrome SX: surgery V: vomiting
index transcriptase inhibitor rpt: repeat syr: syringe
PEG: polyethylene glycol RR: relative risk/risk ratio VA/DoD: Veterans Affairs/Dept of Defense
LVD: left ventricular dysfunction NNT: number needed to treat PEGI: peg-interferon sz: seizure Vag: vaginal
NODM: new onset diabetes mellitus PEN: penicillins RRMS: relapsing remitting multiple T VBAD: vomiting, bleeding,
LVEF: left ventricle ejection fraction sclerosis
LVF: left ventricular function Non-DHP CCB: non-dihydrophyridine PEP: post exposure prophylaxis ↑TC: hypercholesterolemia abdominal mass or unexplained
calcium channel blocker PFO: patent foramen ovale RRR: relative risk reduction t ½: half life weight loss, dysphagia
LVH: left ventricular hypertrophy RSV: respiratory syncytial virus
LVMI: left ventricular mass index NP: no preservatives or PFTs: pulmonary function tests T1DM: type 1 diabetes mellitus VKA: vitamin K antagonist
natriuretic peptide RT: room temperature T2DM: type 2 diabetes mellitus
LVVI: left ventricular volume index PG: propylene glycol RTI: respiratory tract infection VL: viral load
lytes: electrolytes nPEP: nonoccupational post PGA: prostaglandin analogue T3: Iiothyronine VL-ST: very late stent thrombosis
exposure prophylaxis PHTN: pulmonary hypertension RTV: ritonavir T4: levothyroxine VMS: vasomotor symptoms of menopause
M Rx: prescription
NPN: natural product number PHN: post-herpetic neuralgia tab: tablet VPA: valproic acid
M: monitor NPO: nothing by mouth PI: protease inhibitor rxn: reaction TAC: tacrolimus vs: versus
MA: meta-analysis or NRTI: nucleos(t)ide reverse PID: pelvic inflammatory disease S TB: tuberculosis VTE: venous thromboembolism
megesterol acetate transcriptase inhibitor PK: pharmacokinetics S&Sx: signs & symptoms TBE: tick–borne encephalitis W
MACE: major adverse NS: non-significant Pk: peak SABA: short-acting beta-2 agonist Tbsp: tablespoon (~15mL)
SABD: short-acting bronchodilator WBC: white blood cell
cardiovascular events NSa: normal saline PKI: protein kinase inhibitor TBW: total body weight WHO: World Health Organization
MALT: mucosa associated lymphoid NSAID: non-steroidal anti- Pl: placebo SAD: social anxiety disorder TC: total cholesterol Wk(s): weeks
tissue inflammatory drug Plt: platelet SAE: serious adverse event TCA: tricyclic antidepressant(s)
SAIL: Saskatchewan Aids to WMD: weighted mean difference
MAOi: monoamine oxidase inhibitor NSR: normal sinus rhythm PM: postmenopausal TCNs: tetracyclines WPW: Wolff-Parkinson-White sx
Max: maximum NTD: neural tube defect PMC: pseudomembranous colitis Independent Living Td: tetanus, diphtheria WR: weak recommendation
MCI: mild cognitive impairment NYHA: New York Heart Association PMO: postmenopausal osteoporosis SAMA: short-acting muscarinic Tdap: tetanus, diphtheria, pertussis
antagonist wt: weight
MCV: mean corpuscular volume O PMS: premenstrual symptoms TdP: Torsades de Pointes X, Y, Z
OA: osteoarthritis PNE: primary nocturnal enuresis SAP: special access program TEE: transesophageal
MD: maintenance dose SAPT: single antiplatelet therapy XL: extra large or extended release
MDD: major depressive disorder OAB: overactive bladder PNS: parasympathetic nervous sx echocardiogram XOI: xanthine oxidase inhibitor
po: oral SAR: seasonal allergic rhinitis Temp: temporary
MDI: metered dose inhaler OAC: oral anticoagulant SBP: systolic blood pressure yr(s): years; years old
MDS: Myelodysplastic Syndromes OAHA: oral anti-hyperglycemic agent PO4: phosphate TEN: Toxic epidermal necrolysis
SC: subcutaneous TFT: thyroid function tests ZES: Zollinger-Ellison Syndrome
MED: morphine equivalent dose OAT: opioid agonist therapy POAG: primary open angle glaucoma 244
SCI: spinal cord injury (TSH/FT4/FT3)
MF: metformin SCr: serum creatinine