Sonia Studnet Paper
Sonia Studnet Paper
Abstract — We propose and analyze a dielectric mod- is no delay in starting the treatment procedure [4], [5]. Recent
ulated (DM) negative capacitance (NC) fin-field effect advances in field effect transistor (FET) biosensors have added
transistor (FinFET) based biosensor for efficient and label- new dimensions to point-of-care measurements because of
free detection of biomolecular entities. For the first time,
the NC effect on bio-sensing owing to the presence of a their advantages of sensing accuracy, reduced power con-
dielectric-ferroelectricgate oxide stack is investigated. First, sumption, and development costs [6]–[11]. Recently, an FET-
capability of the NC-FinFET is compared with the baseline based biosensor is employed to recognize SARS-COV-2
FinFET as percentage variation in electrical parameters. in patients using nasopharyngeal swab sample [12].
Also, the sensing capability of the proposed device is exam- Several FET-based biosensor based on the inversion
ined with a wide variety of biomolecules with varying dielec-
tric constants. Inclusion of the NC effect in the biosensor mode (IM), accumulation mode, or the tunneling phenom-
exhibits very high sensitivity in terms of the electrical fig- ena [13]–[16] are proposed. Out of these, TFET-based biosen-
ures of merit (FoMs) such as threshold voltage, ION /IOFF -ratio, sors are considered superior but fabrication complexity, low
output conductance, and intrinsic gain with rapid response sensitivity, and ambipolarity of different TFET biosensor mod-
because of the steep subthreshold value. The use of raised els prevent its commercialization [17], [18]. FinFET (FinFET)
source drain (RSD) architecture allows more cavity space
to the biomolecules and, hence, increases the sensitivity device architecture provides more living space to the mole-
and selectivity of the biosensor. All the device simulations cules inside the sensor, thereby exhibiting higher sensitivity
are performed in a 3-D Sentaurus TCAD environment using and selectivity. However, FinFETs are more prone to the
well-calibrated structure. To establish a benchmark, the sen- short channel effects at lower node technology and, hence,
sitivity of the proposed biosensor is also compared with the biosensor designed using the proposed architecture require
published literature in order to determine its effectiveness.
The results of this study can establish NC-FinFET as a viable low power and have low response time for the identification
candidate for label-free DM biosensor applications. of the biomolecules. The basic principle of operation of
FET biosensors involves the variation of oxide capacitance
Index Terms — Biosensor, dielectric modulation, label-
free, negative capacitance (NC)-fin-field effect transis- because of the presence of trapped biomolecules with variable
tor (FinFET) sensitivity, silicon on insulator (SOI). dielectric constants inside the cavity, which causes a change in
the essential electrical parameters of the FET device such as
I. I NTRODUCTION threshold voltage, driving current, subthreshold slope (SS), and
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DIXIT et al.: SENSITIVITY ANALYSIS OF A NOVEL NC FinFET FOR LABEL-FREE BIOSENSING 5205
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5206 IEEE TRANSACTIONS ON ELECTRON DEVICES, VOL. 68, NO. 10, OCTOBER 2021
TABLE I
VALUES OF D IFFERENT PARAMETERS U SED FOR THE S IMULATION OF
THE P ROPOSED F IN FET B IOSENSOR
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DIXIT et al.: SENSITIVITY ANALYSIS OF A NOVEL NC FinFET FOR LABEL-FREE BIOSENSING 5207
TABLE II
E FFECT ON (A) ION /IOFF R ATIO ; (B) T RANSCONDUCTANCE ; AND (C)
T HRESHOLD VOLTAGE OF THE P ROPOSED DM RSD NC-F IN FET
B IOSENSOR D UE TO THE E XISTENCE OF B IOMOLECULES
Fig. 7. Impact of the presence and absence of the biomolecules on the Fig. 9. Spider chart presentation of (a) CR and (b) threshold voltage
energy band diagram under ON- and OFF-operating conditions. versus dielectric values of biomolecules.
Fig. 10. Output characteristics and output conductance (go ) behavior for
Fig. 8. Transfer characteristics behavior for of the NC-FinFET based of the NC-FinFET based label-free biosensor at air (K = 1) and presence
label-free biosensor at air (K = 1) and presence of various biomolecules of various biomolecules (K = 2.3 and 12) for at (a) VDS = 0.05 V and
(K = 2.1/2.3/4.2/6.3/12) for both logarithmic (left y-axis) and linear (right (b) VDS = 0.5 V.
y-axis) at (a) VDS = 0.05 V and (b) VDS = 0.5 V.
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5208 IEEE TRANSACTIONS ON ELECTRON DEVICES, VOL. 68, NO. 10, OCTOBER 2021
TABLE III
S ENSITIVITY A NALYSIS OF THE P ROPOSED DM-RSD NC-F IN FET B IOSENSOR IN T ERMS OF CR,
T HRESHOLD VOLTAGE , AND OFF -C URRENT AT D IFFERENT B IAS VOLTAGES
TABLE IV
B IOSENSOR S ENSITIVITY C OMPARISON W ITH P REVIOUSLY R EPORTED W ORK
C. Sensitivity Analysis where A could be any FoM of the biosensor. We have analyzed
some parameters such as IOFF , Vth , and ION -/IOFF -ratio, which
The effectiveness of any biosensor depends on its capability shows a good deviation in the presence or absence or biomole-
to detect or classify the biomolecules with high accuracy or cules. So, these quantities are used to explain the sensitivity of
precision. Hence, to define the sensitivity, we have used a the proposed biosensor. Fig. 12 gives a pictorial representation
generalized expression in the following equation: of sensitivity parameters SI OFF , SV th , and SCR for K = 2.1,
Abio − Aair 2.3, 4.7, 6.3, and 12. Note that the sensitivity parameters
S A (%) = ∗ 100 (1) exhibit similar trend of increasing uniformly increases with
Aair
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DIXIT et al.: SENSITIVITY ANALYSIS OF A NOVEL NC FinFET FOR LABEL-FREE BIOSENSING 5209
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