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 First published in 2001 by Martin Dunitz.

This edition published in 2010 by Informa Healthcare, Telephone House, 69-77 Paul Street, London EC2A 4LQ, UK.

Simultaneously published in the USA by Informa Healthcare, 52 Vanderbilt Avenue, 7th Floor, New York, NY 10017, USA.

Informa Healthcare is a trading division of Informa UK Ltd. Registered Office: 37–41 Mortimer Street, London W1T 3JH, UK.
Registered in England and Wales number 1072954.

#2010 Informa Healthcare, except as otherwise indicated

No claim to original U.S. Government works

Reprinted material is quoted with permission. Although every effort has been made to ensure that all owners of copyright material
have been acknowledged in this publication, we would be glad to acknowledge in subsequent reprints or editions any omissions
brought to our attention.

All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any
means, electronic, mechanical, photocopying, recording, or otherwise, unless with the prior written permission of the publisher or in
accordance with the provisions of the Copyright, Designs and Patents Act 1988 or under the terms of any licence permitting limited
copying issued by the Copyright Licensing Agency, 90 Tottenham Court Road, London W1P 0LP, UK, or the Copyright Clearance
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Center, Inc., 222 Rosewood Drive, Danvers, MA 01923, USA (http://www.copyright.com/ or telephone 978-750-8400).

Product or corporate names may be trademarks or registered trademarks, and are used only for identification and explanation without
intent to infringe.

This book contains information from reputable sources and although reasonable efforts have been made to publish accurate
information, the publisher makes no warranties (either express or implied) as to the accuracy or fitness for a particular purpose of
the information or advice contained herein. The publisher wishes to make it clear that any views or opinions expressed in this book by
individual authors or contributors are their personal views and opinions and do not necessarily reflect the views/opinions of the
publisher. Any information or guidance contained in this book is intended for use solely by medical professionals strictly as a
For personal use only.

supplement to the medical professional’s own judgement, knowledge of the patient’s medical history, relevant manufacturer’s
instructions and the appropriate best practice guidelines. Because of the rapid advances in medical science, any information or advice
on dosages, procedures, or diagnoses should be independently verified. This book does not indicate whether a particular treatment is
appropriate or suitable for a particular individual. Ultimately it is the sole responsibility of the medical professional to make his or her
own professional judgements, so as appropriately to advise and treat patients. Save for death or personal injury caused by the
publisher’s negligence and to the fullest extent otherwise permitted by law, neither the publisher nor any person engaged or employed
by the publisher shall be responsible or liable for any loss, injury or damage caused to any person or property arising in any way from
the use of this book.

A CIP record for this book is available from the British Library.

Library of Congress Cataloging-in-Publication Data available on application

ISBN-13: 9781853179822

Orders may be sent to: Informa Healthcare, Sheepen Place, Colchester, Essex CO3 3LP, UK
Telephone: +44 (0)20 7017 5540
Email: [email protected]
Website: http://informahealthcarebooks.com/

For corporate sales please contact: [email protected]

For foreign rights please contact: [email protected]
For reprint permissions please contact: [email protected]
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