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Fertilization
i t
MEd sis
ing part 2
FERTILIZATION
_emIaa Sperm OVUM
FERTILIZATION
2M Oocyte arrested
_Enzaas Sperm OVUM
12
mmmm
ploidy INN
idol
2N
spermatogonium
46 Single chromosomes XY
2C
2C
C numberof chromatids
Bloodtestis Barriers
TIGHTfounction bysertolicell
Made
2N
Inspermalocyte
46 Sister chromatids XX
4C yy
4C
IN IN
XX spermatocyte YY
µ
spermatocyte
2C 2C Medicesis
23Single chromosomes f j
x 112 x In Y 112 x In
grass sperm grass sperm grass Sperm grass sperm
Ic Ic Ic Ic
12
mmmm
ploidy INN
idol
2N
Oogonium
46 Single chromosomes
2C
2C
C numberof chromatids
i
2N
ins 46 Sister chromatids
oocyte 4C
4C
PROPHASE I
IN IN
ry ry
2 Oocyte 2 Oocyte
2C 2C Mediesis
METAPHASE IT
x
112
X or
OVUM Polar Polar Polar
1C body body body
FERTILIZATION
mazard Sperm ovum XX
Y 7
Triad Sperm ovum XY
The structure of the sperm
Head Middle
piece
Tail
flagellum
µ
I
T
1
y
f 2
Neck Mitochondrion
Acrosome Nucleus
centriole
The structure of the ovum
Mecitiesis
cell membrane vitellinemembrane
cortical granules Zona pellucida
Cytoplasm in
Spf
nucleolus'tthhg
coronaradiata
Mm3smmB
e i r 3
Nucleus r go 3
follicular cells
Nuclearmembrane
0 of
the corona radiata EPL
2P2
EP3
ZP4
The holy trinity binds
them together
Steps of fertilization
and
i o I o
iiithhy.io
e i r
rg
3
3 oh
MEdesis
u
0
I Capacitation 2 Acrosomal reaction 3 Polyspermy block
4 II
Completion
of meiosis 5
Zygote formation
2Moocyte 0 Ovum
CLEAVAGE
p
Embry 0
Zygote
1 cell
1 cell
Steps of fertilization
and
i o I o
iiithhy.io
e i r
rg
3
3 oh
MEdesis
u
0
I Capacitation 2 Aerosomal reaction 3 Polyspermy block
4 II
Completion
of meiosis 5
Zygote formation
2Moocyte 0 Ovum
I Capacitation Head
capacity Middle
piece Tail
f
is.iagenum
Last step in sperm maturation f
i
f
Ready to fertilize fleek
Mitochondrion
Uterinewall secretionstrigger Capacitation Acrosome Nucleus
centriole
destabilizes
a
sperm'splasmamembrane
Bmmm wer
µ
l MEdesis
Preparesthesperm's tip Catt permeability Kil
g
for the Acrosomal Contraction Hyperactivity
reaction
TT strength speed of flagellum beating
ftp.gswims faster full Capacity
Extremist body
2 AcRosomal Reaction
Recognition between aa.aesperm egg To ensure same species fertilization
why
ofsperm Iafegg
when sperm reachestheZonapellucida actinfilaments will bind 2103 aaaasperm egg
Release of hydrolyticenzymes bythesperm'sAcRosome i digestthruthe Zona pellucida
the Zona pellucida ensures same species fertilization
MEdesis cellmembrane vitellinemembrane
Head
corticalgranules
Zona pellucida
Middle
Piece Ta
f is.la
Cytoplasm
on I o b l
Effie
coronaradiata
nudeoiusflthhg.io
ee 3 r Mitochondrion
Nucleus r 3 AcrosomeNucleus
centriole
Nuclearmembrane
0 follicular cells
of
the corona radiata
3 Polyspermy Block
3N in
Blocks Polyspermy i Blocks Polyploidy
Depolarization
FAST BLOCK EST Lactivation 1Repulsion
ofothersperms
Nat
Rapidonset shortduration
pj
SLOW BLOCK is
slow onset longduration cellmembrane vitellinemembrane
Cattrelease Corticalreaction corticalgranules
Zona pellucida
b
Exocytosis Cortical
ofgranules cytoplasm
on I o
thhg
Nadeau coronaradiata
C A ei r 3
Nucleus 3
Zonapellucida IMPENETRABLE
MEMBRANE
aCutthelink between
Nuclearmembrane
0 of
follicularcells
thecoronaradiata
Zonapellucida plasmamembrane
byreleasinghydrolyticenzymes
4 II
Completion
ofmeiosis
24oocyte 0 ovum
12
mmmm
ploidy z
it'ffilioidd
2N
Oogonium
46 Single chromosomes
2C
2C
c number
ofchromatids
i
2N
jr'soocyte 46 Sister chromatids
4C
PROPHASE I 4C
IN O'Taste
oocyte
2C 2C Medicesis
METAPHASE LT
x
112
X or
OVUM Polar Polar Polar
1C body body body
5
Zygote formation
CLEAVAGE
p
Embryo
Zygote
1 cell
1 cell
CLEAVAGE
I f
Morula
Zygote 12 16 cells
1 cell
Embryo
1 cell
IMPLANTATION
orwww.m
Fan
T
yjh
of
H
g
Bilamminar Embryo Trilaminal embryo
endoderm a
Hypoblast
Primitivestreak
r
Blastocyst cavity a
Blastocele
0
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om
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