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94 views1 page

Activity-Problem

Uploaded by

Dionne Sebastian Doromal
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as DOCX, PDF, TXT or read online on Scribd
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Biochemistry

Individual Activity, Section D


Final term

Instruction:
1. Read and understand carefully each situation. Expound your knowledge in Biochemistry by solving
the problem. Explain very well in your own words, 5 pts for each problem.
2. Use yellow pad with your name in writing your answers.
3. Date due: December 2, lecture time. Beyond the set date and time, output will not be accepted.
4. Copying from one another and directly from the source will NOT be tolerated. Paraphrase facts
obtained. Remember, AI can be detected.
5. Cite all your references.

1. Mary Jane is an actress whose nature of work entails irregular taking of meals. More often than not, she skips
breakfast especially during early shooting calls. With this situation, she complains of headache and weakness from time
to time. Because of her hectic schedule, she has to resort to drinking bottled juices and burgers/fast foods to augment
hunger and stress.
Apply your knowledge in biochemical energy and food metabolism in the case of Mary Jane. Analyze her food
intake and predict the consequence if she does this for a long time.

2. Baby Tristan, a two week old baby developed symptoms which were similar to those of an older sibling who died
shortly after birth. The parents were so alarmed and soon discovered that their son has Maple Syrup Urine Disease
(MSUD), a recessively inherited metabolic disorder.
Describe this disease and explore the genetics of the disease and the ultimate dilemma of treatment options
of this disease.

3. Margarette, is a working student assigned in the canteen and after an exhausting morning work, drank a liquid from
the refrigerator. She was accidentally poisoned and was hospitalized for a long time, being in a very critical condition.
Investigation result showed that the “drink” was laced with cyanide, a sabotage act of an angry employee to destroy the
name of the establishment.
Determine the mechanism of neurotoxin poisoning, describe the mechanism of cyanide poisoning. Relate this
to the function of a neuron by using knowledge of cellular membrane potentials and the actions of neurotoxins at the
molecular level of cell function. Based on this premise, do you think Margarette can recover fully from this accident?

4. In a “weird “party, David came into the room where it is being held and just grabbed a drink from bottles of
antifreeze marked "alcohol" without checking. On the other hand, his friends Gio and Garry, who came just right after
him drank a mixture of ethanol and methanol. Unfortunately David died but Gio and Garry survived.
Explain fully the reason based on your knowledge of enzyme structure and functions.

5. Red Bull is advertised as an “energy drink”. It contains caffeine (80 mg/250 ml), B group vitamins, glucose and
sucrose, taurine and water. Teddy, after a basketball practice went home, and surprisingly knowing from a classmate
that the Biochemistry lecture examination is scheduled on the next day, he immediately purchased 2 cans and drunk
the contents, believing that it will boost his energy in studying. He studied the whole afternoon and later, feeling that he
needs to relax, secretly grabbed a shot of vodka from his father’s home bar.
When we say something gives us “energy” what does that mean? Do you think Red Bull really provides
energy? If it really boosts Teddy’s energy to study, what is the underlying principle behind that? Explain in the
context of both carbohydrate metabolism and caffeine as an ingredient.
Take note also that Teddy also had a shot of vodka. What would be the underlying effect on him? Explain.

6. Michael’s body mass index (BMI) is 32 suggesting obesity. He has high low density lipid (LDL) cholesterol (176 mg/dL),
and smokes cigarettes. His doctor has informed him that he has at least three risk factors for heart disease. The doctor
advises Michael to lose weight, watch his diet, and stop smoking. Michael, a college student, does not know how to go
about making these lifestyle changes. What can you suggest?

7. In a grocery store, you saw that the label on a jar of peanut butter states: Contains no cholesterol. React on this using
your knowledge in lipid biomolecule.

8. People born with a particular genetic defect have low numbers of receptor proteins for cholesterol in their liver cells.
How could this affect their blood cholesterol concentrations? Explain what significance this could have on their
health.

9. How are lipids used by cells? Explain thoroughly.

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