The Laboratory in the Prevention and Control of
Healthcare-associated Infections: Making
healthcare facilities safer
REFERENCES: Week 3: Developing Laboratory Capacity for the Prevention and
Control of HAIs in Healthcare Settings
Why are Hospitals Becoming Unsafe: The impact of COVID-19
• Walsh, T.R. A one-health approach to antimicrobial resistance. Nat Microbiol 3, 854–855
(2018). https://doi.org/10.1038/s41564-018-0208-5
• https://www.nytimes.com/2022/07/13/health/cdc-drug-resistant-infections.html
The Role of the Laboratory in Keeping Hospitals Safe
• https://www.who.int/publications/i/item/WHO-EMP-IAU-2018.01
• Dramowski A, Cotton MF, Whitelaw A. Surveillance of healthcare-associated infection in
hospitalised South African children: Which method performs best?. South African Medical
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• Alemu AY, Endalamaw A, Bayih WA. The burden of healthcare-associated infection in
Ethiopia: a systematic review and meta-analysis. Trop Med Health. 2020 Sep 7;48:77.
Prioritizing Pathogens for Surveillance
• Mathur P, et al. Health-care-associated bloodstream and urinary tract infections in a network
of hospitals in India: a multicentre, hospital-based, prospective surveillance study. The Lancet
Global Health. 2022 Sep 1;10(9):e1317-25.
• https://www.cdcfoundation.org/blog/making-investment-infection-prevention-and-control-
nigeria
Integrated AMR Surveillance: ESBL producing bacteria
• https://www.who.int/indonesia/news/detail/28-08-2019-monitoring-visit-for-esbl-e.-coli---
the-tricycle-project-in-Indonesia
• https://www.who.int/initiatives/glass/glass-modules-7
• https://www.canada.ca/en/public-health/services/surveillance/canadian-integrated-
program-antimicrobial-resistance-surveillance-cipars
The Laboratory in the Prevention and Control of
Healthcare-associated Infections: Making
healthcare facilities safer
REFERENCES: Week 3: Developing Laboratory Capacity for the Prevention and
Control of HAIs in Healthcare Settings
Guidance on Outbreak Investigations
• https://www.cdc.gov/hai/outbreaks/outbreaktoolkit.html
• Reintjes R, Zanuzdana A. Outbreak Investigations. Modern Infectious Disease Epidemiology.
2009 Jul 28:159–76. doi: 10.1007/978-0-387-93835-6_9. PMCID: PMC7187955.
https://youtu.be/kYFIqTbRd2o
Case Studies and Self-study
• Rosenthal VD, et al. Impact of the International Nosocomial Infection Control Consortium's
multidimensional approach on rates of ventilator-associated pneumonia in 14 intensive care
units in 11 hospitals of 5 cities within Argentina. Am J Infect Control. 2018 Jun;46(6):674-679.
https://www.sciencedirect.com/science/article/abs/pii/S0196655317312907
• Antimicrobial stewardship programmes in health-care facilities in low- and middle-income
countries. A WHO practical toolkit 2019.
• Schwaber MJ, et al., Israel Carbapenem-Resistant Enterobacteriaceae Working Group.
Containment of a country-wide outbreak of carbapenem-resistant Klebsiella pneumoniae in
Israeli hospitals via a nationally implemented intervention. Clin Infect Dis. 2011 Apr
1;52(7):848-55.
• Zhao Y, et al. Outbreak of carbapenem-resistant Acinetobacter baumannii carrying the
carbapenemase OXA-23 in ICU of the eastern Heilongjiang Province, China. BMC Infect Dis.
2019 May 22;19(1):452. doi: 10.1186/s12879-019-4073-5. Erratum in: BMC Infect Dis. 2019
Jul 15;19(1):621.
Laboratory Systems and Diagnostics
• https://apps.who.int/iris/handle/10665/326480
• https://msfaccess.org/msf-mini-lab-project
https://youtu.be/XgPfA1VfQVY
The Laboratory in the Prevention and Control of
Healthcare-associated Infections: Making
healthcare facilities safer
REFERENCES: Week 3: Developing Laboratory Capacity for the Prevention and
Control of HAIs in Healthcare Settings
Strengthening Laboratory Quality
• LMTA and SLIPTA (WHO).
https://www.slmta.org/#:~:text=While%20SLIPTA%20measures%20the%20laboratory,to%20
with%20training%20and%20mentoring
• QMS 12 building blocks (CLSI). https://clsi.org/standards/products/quality-management-
systems/
• Quality assurance Handbook (CDC).
https://www.who.int/publications/i/item/9789241508179
• AST Quality Control (QC) panels for AST. https://clsi.org/media/2518/clsi_iqcp_microinfo.pdf
• The WHO SLIPTA Stepwise Process. https://www.afro.who.int/publications/who-guide-
stepwise-laboratory-improvement-process-towards-accreditation-slipta-african
• Jan Jacobs et al. 2019 Frontiers.
https://www.frontiersin.org/articles/10.3389/fmed.2019.00205/full
• Ombelet S, et al. Best Practices of Blood Cultures in Low- and Middle-Income Countries.
Front Med (Lausanne). 2019 Jun 18;6:131.
Continuous Professional Development
• https://www.ahrq.gov/health-literacy/improve/precautions/tool2b.html