VISVESVARAYA TECHNOLOGICAL UNIVERSITY

“JNANA SANGAMA”, BELAGAVI-590018, KARNATAKA

2022-2023

BIOLOGY FOR ENGINEERS [21BE45]

Seminar Report on
“BIOPRINTING TECHNIQUES AND MATERIALS”
Submitted in partial fulfillment of the requirements for the award of the degree of
BACHELOR OF ENGINEERING
in
INFORMATION SCIENCE AND ENGINEERING
TEAM: BLACK

RAHUL M WALI 1AT21IS081 SRAVAN KUMAR 1AT21IS110

SIBIRAJ 1AT21IS107 SANJU M 1AT21IS098
REHAN AHMED 1AT21IS086 SYED ASIL 1AT21IS116
SWAROOP SHETTY 1AT21IS114 NIROSH 1AT21IS073
SANSKAR 1AT21IS099 y MOHAMMED SAQLAIN 1AT21IS063

Under the Guidance of

Mrs. Priyanka
Assistant Professor
Dept of BS&E
Atria I.T

ATRIA INSTITUTE OF TECHNOLOGY

(Affiliated to Visvesvaraya Technological University)
ASKB Campus, Anand Nagar
Bengaluru-560024
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 CONTENTS

Sl.no Topic Page number

1 INTRODUCTION 3
2 PRINCIPLE OF WORKING 4

3 INSTRUMENTATION 5

4 ADVANTAGES and DISADVANTAGES 6

5 CONCLUSION 7

6 REFERENCES 8

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 INTRODUCTION

Bioprinting, at the nexus of biology, engineering, and medicine, offers revolutionary potential in
tissue engineering and regenerative medicine. It enables the precise creation of three-dimensional
biological structures using biocompatible materials and living cells. Various bioprinting techniques, such
as inkjet, extrusion-based, laser-assisted, and microvalve-based, provide diverse options for crafting
intricate tissues. The choice of biomaterials, like natural hydrogels and synthetic polymers, is pivotal for
ensuring biocompatibility and an optimal environment for cell growth. Bioprinting promises
personalized treatments, reduced transplant rejection risks, and expedited drug development via in vitro
models. Despite existing challenges, such as vascularization and regulatory hurdles, bioprinting stands
poised to revolutionize healthcare and address critical medical needs..

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 PRINCIPLE OF WORKING
Bioprinting operates on the principle of layer-by-layer deposition of biocompatible materials and
living cells to fabricate three-dimensional biological structures. Various bioprinting techniques, such as
inkjet, extrusion-based, laser-assisted, or microvalve-based, are employed to precisely position bioink
(cell-laden solutions) onto a substrate. These techniques rely on computer-aided designs and precise
control mechanisms to create complex tissue patterns. The chosen biomaterials, typically natural
hydrogels or synthetic polymers, provide a supportive environment for cell growth and tissue
development. The integration of cells is central to bioprinting's success, and the cells must remain viable
throughout the printing process. This layer-by-layer approach allows for the creation of intricate,
functional tissues and organs tailored to specific medical needs.

3D Printing of Skin: Bioprinting Techniques

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 INSTRUMENTATION
Bioprinting Instrumentation: Precision in Tissue Fabrication :
Bioprinting relies on specialized instruments, including computer-controlled platforms, print
heads, and bioink cartridges. These components work together to deposit biocompatible materials and
living cells layer by layer, following digital designs. Monitoring tools ensure accuracy, while
environmental conditions are maintained for cell viability, enabling precise and reproducible tissue
fabrication.

CELL SEEDING
Types of Bioprinting Instruments

Bioprinting instruments are essential for the fabrication of complex biological structures.
Several types of bioprinting instruments exist, each with its unique capabilities and
applications. These instruments play a crucial role in advancing tissue engineering and
regenerative medicine.
1. Inkjet Bioprinters: Inkjet bioprinters operate by ejecting droplets of bioink onto a substrate,
allowing for precise layering of cells and materials. They are commonly used for applications
requiring high-resolution patterning and are well-suited for creating tissue models.
2. Extrusion-Based Bioprinters: Extrusion-based bioprinters use a nozzle to continuously
dispense bioink, making them suitable for building thicker, more complex structures. These
instruments are versatile and widely employed in tissue engineering.
3. Laser-Assisted Bioprinters: Laser-assisted bioprinters use focused laser beams to position
cells and materials with extreme precision. They are ideal for creating intricate, high-resolution
tissue constructs.

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 ADVANTAGES and DISADVANTAGES
ADVANTAGES

Precision : Bioprinting instruments enable the precise placement of cells and biomaterials, allowing for
the creation of complex, customized tissue structures.
Reduced Transplantation Risks: Bioprinting can produce tissues tailored to a patient's specific needs,
reducing the risk of transplant rejection.
Accelerated Research: These instruments provide valuable in vitro models for drug testing and disease
research, potentially speeding up pharmaceutical development.
Personalized Medicine: Bioprinting holds the promise of personalized medicine, offering patient-
specific solutions for healthcare.

PRINTING ORGANS

DISADVANTAGES :-
Complexity: Bioprinting instruments require specialized knowledge and expertise, limiting widespread
adoption.
Cost: High initial and operational costs can be a barrier to entry for many researchers and healthcare
institutions.
Cell Viability: Ensuring the viability of cells during and after printing remains a challenge, impacting
the functionality of bioprinted tissues.

Regulatory Hurdles: Regulatory approval for bioprinted products can be a lengthy and complex
process, slowing down their integration into mainstream healthcare

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 CONCLUSION

In conclusion, self-healing bio-concrete stands as a remarkable testament to the power of

innovation in addressing long-standing challenges in the construction industry. By blending the
principles of biotechnology and engineering, this extraordinary material exemplifies a sustainable
approach to building resilient and enduring infrastructure. The ability of bio-concrete to autonomously
repair cracks not only extends the lifespan of structures but also reduces maintenance demands and
associated costs. As we look ahead, the adoption of self-healing bio-concrete holds the promise of
fostering a more environmentally conscious and economically efficient construction landscape, where
structures not only withstand the test of time but also contribute to a greener and more sustainable future.
This convergence of science and construction encapsulates the spirit of progress, offering a tangible
glimpse into the potential of technology to reshape the way we build and maintain the world around us.

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 REFERENCES

https://www.researchgate.net/publication/303172092_A_review_paper_on_self_healing_concrete
https://www.irjet.net/archives/V5/i5/IRJET-V5I5732.pdf
file:///C:/Users/care6/Downloads/105252-238922-1-PB.pdf

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