Recommended Books (Latest edition):
1. Y.K. Sing, Environmental Science, New Age International Pvt, Publishers,
Bangalore
2. Agarwal, K.C. 2001 Environmental Biology, Nidi Publ. Ltd. Bikaner.
3. Bharucha Erach, The Biodiversity of India, Mapin Pu blishing Pvt. Ltd.,
Ahmedabad – 380 013, India,
4. Brunner R.C., 1989, Hazardous Waste Incineration, McGraw Hill Inc. 480p
5. Clark R.S., Marine Pollution, Clanderson Press Oxford
6. Cunningham, W.P. Cooper, T.H. Gorhani, E & Hepworth, M.T. 2001,
Environmental Encyclopedia, Jaico Publ. House, Mumbai, 1196p
7. De A.K., Environmental Chemistry, Wiley Eastern Ltd.
8. Down of Earth, Centre for Science and Environment
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SEMESTER III
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BP301T. PHARMACEUTICAL ORGANIC CHEMISTRY –II (Theory)
45 Hours
Scope: This subject deals with general methods of preparation and reactions of some
organic compounds. Reactivity of organic compounds are also studied here. The syllabus
emphasizes on mechanisms and orientation of reactions. Chemistry of fats and oils are
also included in the syllabus.
Objectives: Upon completion of the course the student shall be able to
1. write the structure, name and the type of isomerism of the organic compound
2. write the reaction, name the reaction and orientation of reactions
3. account for reactivity/stability of compounds,
4. prepare organic compounds
Course Content:
General methods of preparation and reactions of compounds superscripted with asterisk (*) to be
explained
To emphasize on definition, types, classification, principles/mechanisms, applications, examples
and differences
UNIT I 10 Hours
Benzene and its derivatives
A. Analytical, synthetic and other evidences in the derivation of structure
of benzene, Orbital picture, resonance in benzene, aromatic
characters, Huckel’s rule
B. Reactions of benzene - nitration, sulphonation, halogenation-
reactivity, Friedelcrafts alkylation- reactivity, limitations,
Friedelcrafts acylation.
C. Substituents, effect of substituents on reactivity and orientation of
mono substituted benzene compounds towards electrophilic
substitution reaction
D. Structure and uses of DDT, Saccharin, BHC and Chloramine
UNIT II 10 Hours
Phenols* - Acidity of phenols, effect of substituents on acidity, qualitative
tests, Structure and uses of phenol, cresols, resorcinol, naphthols
Aromatic Amines* - Basicity of amines, effect of substituents on basicity,
and synthetic uses of aryl diazonium salts
Aromatic Acids* –Acidity, effect of substituents on acidity and
important reactions of benzoic acid.
UNIT III
10 Hours
Fats and Oils
a. Fatty acids – reactions.
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b. Hydrolysis, Hydrogenation, Saponification and Rancidity of oils, Drying
oils.
c. Analytical constants – Acid value, Saponification value, Ester value,
Iodine value, Acetyl value, Reichert Meissl (RM) value – significance and
principle involved in their determination.
UNIT IV 08 Hours
Polynuclear hydrocarbons:
a. Synthesis, reactions
b. Structure and medicinal uses of Naphthalene, Phenanthrene, Anthracene,
Diphenylmethane, Triphenylmethane and their derivatives
UNIT V 07 Hours
Cyclo alkanes*
Stabilities – Baeyer’s strain theory, limitation of Baeyer’s strain theory,
Coulson and Moffitt’s modification, Sachse Mohr’s theory (Theory of
strainless rings), reactions of cyclopropane and cyclobutane only
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