Antipsychotic

Generic aripiprazole risperidone quetiapine

Brand Abilify Risperdal Seroquel
Therapeutic Antipsychotic Antipsychotic Antipsychotic
Tablet/ODT Tablet/ODT Tablet/ER Tablet

Dosage forms Solution Solution

IM Suspension

Bipolar disorder-
Manic episode or maintenance Autism
Schizophrenia Manic or Mixed Bipolar I Bipolar
Indications Depression Schizophrenia Schizophrenia
Tourette's Major Depressive disorder

Take with food but avoid alcohol or

Avoid alcohol Take with food but avoid alcohol
other CNS depressants
Avoid activities requiring mental alertness Avoid activities requiring mental Avoid activities requiring mental
or coordination until drug effects are alertness or coordination until drug alertness or coordination until drug
realized effects are known. effects are known.
Report signs/symptoms of hyperglycemia,
Use caution during activities leading to Use caution during activities leading to
extrapyramidal effects, and neuroleptic
an increased core temperature. an increased core temperature.
malignant syndrome
Report worsening depression, suicidal
Rise slowly from a sitting/supine
ideation, or unusual changes in behavior, Rise slowly from a sitting/supine position
position
especially at initiation of therapy or with
PT Counseling dose changes. Children, adolescents, and Report signs/symptoms of Report signs/symptoms of
young adults are at higher risk for these hyperglycemia, arrhythmia, tardive hyperglycemia, arrhythmia, tardive
effects during the first few months of dyskinesia, or neuroleptic malignant dyskinesia, or neuroleptic malignant
therapy syndrome syndrome
Keep dispersible tablet in blister pack
Drug may impair heat regulation. Drug may
until use. Place on tongue and swallow
also lower seizure threshold. Patients with
after dissolved. Oral solution may be
history of seizures or conditions that lower
mixed with water, coffee, orange juice,
seizure threshold should report increased
or low fat milk, but should not be mixed
seizure activity
with cola or tea.
Avoid sudden discontinuation
 Anticonvulsant
Generic divalproex phenytoin gabapentin lamotrigine levetiracetam oxcarbazepine pregabalin topiramate
Brand Depakote Dilantin Neurontin Lamictal Keppra Trileptal Lyrica Topamax
Therapeutic Anticonvulsant Anticonvulsant Anticonvulsant Anticonvulsant Anticonvulsant Anticonvulsant Anticonvulsant Anticonvulsant
ER/DR Tablet Chewable Tablet Tablet/ER Tablet Tablet/Chewable/ODT/ER Tablet/ODT/ER Tablet/ER Tablet
DR Capsule Sprinkles Capsule Capsule Capsule Capsule/ER/ER Sprinkle
Dosage forms Solution Solution Solution
Suspension Suspension Suspension

Absence seizure Tonic Clonic Seizure Bipolar I Tonic Clonic Seizure Neuropathic Pain Tonic Clonic Seizure
Complex partial epileptic
seizure Partial Seizure Partial Seizure Partial Seizure Partial Seizure Partial Seizure
Indications
Manic Bipolar Postherpetic neuralgia Postherpetic neuralgia
Myoclonic Seizure Fibromyalgia Migraine prophylaxis

First dose on 1st day should be

May cause nausea, diplopia,
Take with food to avoid GI taken at bedtime. ER Take with food, but not alcohol,
Avoid Alcohol Avoid Alcohol Avoid Alcohol nervousness, confusion, and
irritation. Avoid alcohol formulation should be taken grapefruit, or grapefruit juice
many other CNS effects
with the evening meal
Avoid activities requiring mental Avoid activities requiring mental Avoid activities requiring mental Avoid activities requiring mental Avoid activities requiring mental Avoid activities requiring mental Avoid activities requiring mental
alertness until drug effects are alertness until drug effects are alertness until drug effects are Review driving restrictions for alertness until drug effects are alertness until drug effects are alertness until drug effects are alertness until drug effects are
realized; drug may cause realized; drug may cause realized; drug may cause patients with seizures realized; drug may cause realized; drug may cause realized; drug may cause realized; drug may cause
somnolence or dizziness somnolence or dizziness somnolence or dizziness somnolence or dizziness somnolence or dizziness somnolence or dizziness somnolence or dizziness
Report signs/symptoms of Seek medical attention if rash
Do not discontinue drug Do not discontinue drug Avoid sudden discontinuation of Avoid sudden discontinuation of Avoid sudden discontinuation of Avoid sudden discontinuation of
pancytopenia, hepatotoxicity, develops. Slow titration
abruptly, as this may precipitate abruptly, as this may precipitate drug, may increase seizure drug, may increase seizure drug, may increase seizure drug, may increase seizure
systemic lupus erythematosus, necessary to minimize side
status epilepticus. status epilepticus. activity activity activity activity
or severe skin reaction effects.
PT Counseling Sprinkle capsules can be Suspension requires extensive Report mood swings, agitation,
Advise patient to report
Report worsening depression, Talk to your health-care signs/symptoms of serious Seek medical attention for new
swallowed whole or opened and shaking before administration. hostile behavior, suicidal
suicidal ideation, or unusual provider if you become or plan dermatologic reactions, eye problems or high body
sprinkled onto soft food; do not Do not crush extended-release ideation, or unusual changes in
changes in behavior to become pregnant. myelosuppression, or temperature
chew. capsules behavior.
hepatotoxicity
Instruct patient to swallow Suspension should be shaken
extended-release tablet whole; well and dose prepared
Many drug interactions; check do not chew, break, or crush. immediately using oral dosing
Place oral disintegrating tablet May decrease sweating; avoid
with health-care provider when Wait 2 h after antacid before ODT tablet may be placed on syringe. Suspension can be Solution must be used within 45
formulation on tongue and hot temperatures (including hot
starting new medications or OTC taking gabapentin. the tongue and dissolved with a mixed in a small glass of water d of first opening the bottle.
allow to dissolve tubs and saunas).
products sip of water, or dissolved in just prior to administration or
approximately 15 mL of liquid may be swallowed directly from
in a cup and taken immediately the syringe
 Antiparkinsonian Alzheimer's
Generic benztropine ropinirole pramipexole carbidopa/levodopa donepezil memantine
Brand Cogentin Requip Mirapex Sinemet Aricept Namenda
Therapeutic Antiparkinsonian Antiparkinsonian Antiparkinsonian Antiparkinsonian Alzheimer's Alzheimer's
Tablet Tablet/ER Tablet/ER Tablet/ER/ODT Tablet/ODT Tablet
ER Capsule ER Capsule
Dosage forms
Solution

Extrapyramidal Disease Alzheimer's/Dementia: mild- Alzheimer's Disease

Parkinsonism Parkinson Disease Parkinson Disease Parkinson Disease severe
Indications
Restless Leg Syndrome Restless Leg Syndrome

Take at bedtime, with or May be taken with or without

Avoid alcohol Avoid alcohol/CNS Depressants Avoid alcohol/CNS Depressants
without food. food
Drug may impair heat
regulation. Advise patient to use
Avoid sudden discontinuation of If you are using the oral The oral solution is packaged
caution with activities leading to Do not discontinue abruptly, as Allow disintegrating tablet to
drug, it increases risk of disintegrating tabs, place on top with a dosing device that should
an increased core temperature, this may cause emergent dissolve on tongue and follow
neuroleptic malignancy of the tongue; does not require be used to administer the
such as strenuous exercise, hyperpyrexia and confusion. with a glass of water.
syndrome water or swallowing. medication.
exposure to extreme heat, or
dehydration
Adverse effects may be more
Patient should avoid activities Patient should avoid activities Patient should avoid activities
frequent at dose escalation and
PT Counseling requiring mental alertness or requiring mental alertness or requiring mental alertness or
tend to resolve with continued
coordination until drug effects coordination until drug effects coordination until drug effects
use. Report signs/symptoms of
are realized are realized are realized
GI bleeding.
Instruct patient to report
sudden muscle weakness or Rise slowly from sitting/lying- Report new or increased
stiffness, and signs/symptoms of down position. Report new gambling urges, sexual urges,
tardive dyskinesia (tongue onset or exacerbation of compulsive eating or buying, as
thrusting, facial grimacing/tics, dyskinesia, changes in BP, well as new-onset or worsening
random movements of fainting, or unusual urges. dyskinesia.
extremities).
Take with food if nausea occurs
 MISC
Generic potassium isosorbide mononitrate nitroglycerin digoxin amiodarone
Brand Klor-Con Imdur Minitran, Nitrostat, Nitro-Dur Lanoxin Cordarone
Therapeutic Electrolyte Antianginal Antianginal Antiarrhythmic Antiarrhythmic
ER Tablet/Effervescent Tab IR/ER Tablet Sublingual Tablet Tablet
ER Capsule ER Capsule
Dosage forms Solution Sublingual Solution Solution
Powder for Solution Transdermal Patch/Ointment
Rectal Ointment
Translingual Aerosol Solution

Hypokalemia Angina prophylaxis Acute Angina or prophylaxis Atrial fibrillation Ventricular arrythmia
Indications
Heart Failure

Do not eat or drink after placement of

Take with food. Take the powder, granule, take this medicine on an empty stomach with at Take after morning meals (and Take consistently with regard to
tablets. Spray should be sprayed onto or
or oral liquid only after mixing in 4 oz of least half a glass of water after evening meals if giving in meals but avoid taking with
under tongue; do not inhale; do not spit
water or juice. Avoid drinking alcohol divided doses) grapefruit or grapefruit juice
out or rinse mouth after use
Crush or break only specifically designed
This medicine can cause dizziness. Avoid driving, Report signs/symptoms of Use sunscreen, avoid tanning
extended-release formulations. Capsules
using machines, or doing anything else that could bradycardia. Do not discontinue beds and prolonged sun
may be opened, sprinkled on apple sauce,
be dangerous if not alert. drug suddenly. exposure.
and ingested immediately.
Sit prior to using sublingual tablets,
Report signs/symptoms of
PT Counseling Completely dissolve effervescent tablets in Stand up slowly if this medicine causes light- lingual aerosol, or spray.
cardiac arrhythmias, pulmonary
liquid and sip slowly over a 5-10 min period. headedness from orthostatic hypotension Rise slowly from a sitting position in
toxicity, or liver toxicity
order to prevent light-headedness.
This medicine can cause headaches, which is a Allow a 10- to 12-h/d drug-free interval
Multiple drug interactions so
sign that the medicine is working. Acetaminophen to avoid development of nitrate
inform providers about all
may be used to relieve the headache. tolerance for both patches and
medications you are taking
Talk with your doctor if the headache is severe extended-release capsules.
Tablet should be dissolved under tongue Patient medication guide must
Swallow the extended-release tablet whole. Do
or in buccal pouch at 1st sign of angina; be dispensed with this
not break, crush, or chew it
do not swallow or chew tablet medication.
Do not stop using this medicine suddenly without
Do not use with phosphodiesterase
asking a health-care provider. The dose may need
inhibitors, which may result in
to be slowly decreased before stopping it
hypotension
completely
Avoid concomitant use of erectile dysfunction Avoid concurrent use of alcohol, CNS
medications as this may increase risk of severe depressants, antihypertensives, or other
hypotension drugs that cause hypotension.
Scored tablets may be split. The ointment may stain clothing.
 Antihypertensive
Generic furosemide chlorthalidone Hydrochlorothiazide triamterene/HTCZ spironalactone doxazosin terazosin
Brand Lasix Hygroton, Thalitone Esidrix Dyazide, Maxzide Aldactone Cardura Hytrin
Therapeutic Antihypertensive Antihypertensive Antihypertensive Antihypertensive Antihypertensive Antihypertensive Antihypertensive
Class (FYI) Loop Diuretic Thiazide Diuretic Thiazide Diuretic Potassium Sparing Diuretic Potassium Sparing Diuretic α1-Adrenergic Blocker α1-Adrenergic Blocker
Tablet Tablet Tablet Tablet Tablet Tablet/ER
Capsule Capsule Capsule
Dosage forms
Solution

Hypertension Hypertension Hypertension Hypertension Hypertension Hypertension Hypertension

Edema realated to heart Edema related to heart
Edema Edema Edema
failure, renal failure failure
BPH (benign prostatic BPH (benign prostatic
Indications Heart Failure
hyperplasia) hyperplasia)
Nephrotic Syndrome
Hypokalemia

Avoid alcohol (may cause Avoid alcohol (may cause Avoid alcohol (may cause Avoid alcohol (may cause Avoid alcohol (may cause
hypotension) and NSAIDs (may hypotension) and NSAIDs (may hypotension) and NSAIDs (may hypotension) and NSAIDs (may hypotension) and NSAIDs (may Avoid Alcohol
decrease effectiveness) decrease effectiveness) decrease effectiveness) decrease effectiveness) decrease effectiveness)
Avoid sudden discontinuation of
Increased risk of sun sensitivity; Increased risk of sun sensitivity;
drug, as this may cause rebound
use sunscreen and avoid tanning use sunscreen and avoid tanning
hypertension.
Avoid activities requiring This medicine may cause This medicine may cause
Avoid activities requiring Avoid activities requiring
coordination until drug effects dizziness or blurred vision. Avoid dizziness or blurred vision. Avoid
coordination until drug effects coordination until drug effects
are realized, as drug may cause driving, using machinery, or May cause dizziness May cause dizziness driving, using machinery, or
are realized, as drug may cause are realized, as drug may cause
dizziness, vertigo, or blurred doing anything else that could doing anything else that could
dizziness, vertigo dizziness, somnolence
vision. be dangerous if not alert. be dangerous if not alert.
Report signs/symptoms of Instruct patient to report Report signs/symptoms of
Rise slowly from a sitting/lying Rise slowly from a sitting/lying
PT Counseling hypotension, decreased urine signs/symptoms of dyspnea, Report signs/symptoms of Use with caution in patients hyperkalemia (muscle
position, as this drug may cause position, as this drug may cause
output, or ototoxicity; severe hypotension, gout, or heart hypotension with sulfonamide allergy weakness, fatigue, bradycardia)
orthostatic hypotension orthostatic hypotension
skin reactions failure. and hyponatremia (confusion,
May be taken with or without dry mouth, thirst, weakness, Initial dose should be taken with Take drug at bedtime to
Take in the morning with food food. Take early in the day to hypotension, decreased breakfast, particularly with minimize side effects, especially
avoid nocturia. urination). sustained release products the 1st dose.
Syncope or loss of Syncope or loss of
consciousness is possible with consciousness is possible with
Avoid foods that are high in Avoid foods that are high in
Eat high-potassium foods, as 1st dose or dose increases, 1st dose or dose increases,
Eat high-potassium foods during potassium, potassium potassium, potassium
directed by health-care especially if patient is in an especially if patient is in an
therapy supplements or potassium- supplements or potassium-
professional. upright position. Report upright position. Report
containing salt substitutes. containing salt substitutes.
priapism to health care provider priapism to health care provider
immediately. immediately.
 Antihypertensive
Generic clonidine propranolol atenolol metoprolol carvedilol nebivolol hydralazine
Brand Catapres Inderal Tenormin Toprol Coreg Bystolic Apresoline
Therapeutic Antihypertensive Antihypertensive Antihypertensive Antihypertensive Antihypertensive Antihypertensive Antihypertensive
Class (FYI) α2-Adrenergic Blocker Beta Blocker Beta Blocker Beta Blocker Alpha/Beta Blocker B1 Selective Peripheral Vasodilator
Tablet/ER Tablet Tablet Tablet Tablet Tablet
ER Capsule ER Capsule
Dosage forms Solution
Transdermal Patch

Hypertension Hypertension Hypertension Hypertension Hypertension Hypertension Hypertension

ADHD Angina pectoris Angina pectoris Angina
Indications Cardiac dysrythmia Heart Failure Heart Failure
Impaired left ventricle
Migraine prophylaxis AMI function-post MI

Avoid alcohol, CNS depressants Avoid alcohol Avoid alcohol Avoid alcohol
Avoid driving, using machinery,
Use caution with driving and This medicine may cause This medicine may cause This medicine may cause
or doing anything else that
other tasks requiring alertness. dizziness dizziness dizziness
could be dangerous if not alert.
Diabetic patients should Diabetic patients should Diabetic patients should Diabetic patients should Diabetic patients should
May cause nausea, vomiting,
carefully follow blood glucose as carefully follow blood glucose as carefully follow blood glucose as carefully follow blood glucose as carefully follow blood glucose as
insomnia, constipation, fatigue
beta-blockers may mask beta-blockers may mask beta-blockers may mask beta-blockers may mask beta-blockers may mask
or dry mouth
symptoms of hypoglycemia. symptoms of hypoglycemia. symptoms of hypoglycemia. symptoms of hypoglycemia. symptoms of hypoglycemia.
Patient should report chest
Report signs/symptoms of Report signs/symptoms of heart
pain, palpitations,
hypotension, exacerbation of Report signs/symptoms of failure, bradyarrhythmias, . Report signs/symptoms of
signs/symptoms of
angina peripheral edema, hypotension, CHF, or bronchospasm, hypotension, hypotension, worsening heart
tachyarrhythmia, hypotension,
fatigue, hypotension, or hepatic exacerbation of angina with syncope, or exacerbation of failure, or bronchospastic
agranulocytosis, systemic lupus
dysfunction with initial dosing initial dosing and dose changes. angina with initial dosing and disease
PT Counseling erythematosus, or
and dose changes. dose changes.
hepatotoxicity.
Avoid abrupt discontinuation; Avoid abrupt discontinuation; Avoid abrupt discontinuation; Avoid abrupt discontinuation;
Avoid abrupt discontinuation to Avoid abrupt discontinuation to Avoid abrupt discontinuation to
exacerbations of angina may exacerbations of angina may exacerbations of angina may exacerbations of angina may
avoid rebound hypertension. avoid rebound hypertension. avoid rebound hypertension.
occur occur occur occur
Swallow extended-release tablet
whole. Apply patch to hairless
Take immediate-release tablets
area of intact skin on upper
on an empty stomach; ER can be
outer arm or chest; rotate patch Take on an empty stomach Take on an empty stomach Take carvedilol with food or milk
taken with or without food but
location. If patch loosens during
consistently
the 7-d wearing, secure
adhesive cover
Drug may cause sexual side
effects, fatigue, and depression
 Antihypertensive
Generic benazepril enalapril lisinopril quinapril ramipril
Brand Lotensin Vasotec Prinivil, Zestril Accupril Altace
Therapeutic Antihypertensive Antihypertensive Antihypertensive Antihypertensive Antihypertensive
Class (FYI) ACE Inhibitior ACE Inhibitior ACE Inhibitior ACE Inhibitior ACE Inhibitior
Tablet Tablet Tablet Tablet
Capsule
Dosage forms
Solution

Hypertension Hypertension Hypertension Hypertension Hypertension

Heart Failure Heart Failure Heart Failure Heart Failure
Indications
Kidney Disease Acute MI Risk of stroke, MI, death

Most common adverse effect is

dry cough.
May cause dizziness that may May cause dizziness that may May cause dizziness that may May cause dizziness that may
worsen if dehydrated worsen if dehydrated worsen if dehydrated worsen if dehydrated
Seek medical attention
Avoid sudden discontinuation;
immediately if you experience
PT Counseling any facial swelling rebound hypertension can occur

Avoid pregnancy. Avoid pregnancy. Avoid pregnancy. Avoid pregnancy.

Use potassium supplements or Use potassium supplements or Use potassium supplements or Use potassium supplements or Use potassium supplements or
salt substitutes only under salt substitutes only under salt substitutes only under salt substitutes only under salt substitutes only under
medical supervision. medical supervision. medical supervision. medical supervision. medical supervision.
Take at the same time daily.
 Antihypertensive
Generic losartan olmesartan valsartan diltiazem verapamil amlodipine nifedipine
Cardizem, Dilacor XR,
Brand
Cozaar Benicar Diovan Taztia XT, Tiazac Calan/SR, Isoptin SR Norvasc Adalat CC, Procardia XL
Therapeutic Antihypertensive Antihypertensive Antihypertensive Antihypertensive Antihypertensive Antihypertensive Antihypertensive
Class (FYI) ARB ARB ARB Calcium Channel Blocker Calcium Channel Blocker Calcium Channel Blocker Calcium Channel Blocker
Tablet Tablet Tablet Tablet/ER Tablet/ER Tablet ER Tablet
Capsule/ER 12hr/ER 24 hr ER Capsule Capsule
Dosage forms

Hypertension Hypertension Hypertension Hypertension Hypertension Hypertension Hypertension

Diabetic nephropathy Heart Failure Stable angina Angina Stable/Variant Angina Stable/Variant Angina
Reduce risk of MI Atrial Arrythmia Atrial Arrythmia
cerebrovascular accident, in Paroxysmal supraventricular
Indications hypertensive patients with tachycardia
left ventricular hypertrophy;
prophylaxis, diabetic
nephropathy

Avoid sudden discontinuation; This drug is available in multiple Avoid sudden discontinuation; Avoid sudden discontinuation;
May cause orthostatic
rebound hypertension can Avoid sudden discontinuation brand names with varying rebound hypertension can rebound hypertension can
hypotension.
occur. properties by brand occur. occur.
Avoid activities that could be
dangerous if dizziness occurs at
may cause dizziness. Avoid follow administration May cause dizziness; avoid
initiation of therapy. Dizziness
May cause dizziness that may May cause dizziness that may driving, using machinery, or instructions specific to the Rise slowly from a sitting or driving or using hazardous
may be worse if too much water
worsen if dehydrated worsen if dehydrated doing anything else that could prescribed brand with regards lying position to avoid dizziness. machinery until effects are
is lost from the body due to
be dangerous if not alert to meals and timing. known.
excessive sweating, diarrhea, or
vomiting.
PT Counseling Seek medical attention if Seek medical attention if
Report symptomatic Report symptomatic
report signs/symptoms of Report signs/symptoms of
angioedema, excessive fluid angioedema, excessive fluid hypotension or exacerbation of hypotension, exacerbation of
hypotension, bradyarrhythmia, hypotension, bradyarrhythmia,
loss, hyperkalemia, reduction in loss, hyperkalemia, reduction in angina with initial dosing and angina, peripheral edema,
peripheral edema, or syncope. peripheral edema, or syncope.
urination, or jaundice occurs urination, or jaundice occurs dose changes fatigue, or hypotension
Do not crush or chew extended-
release products. Contents of Report signs/symptoms of
Use potassium supplements or Use potassium supplements or Use potassium supplements or
extended-release capsules may peripheral edema, fatigue, Take Adalat CC on an empty
salt substitutes only under salt substitutes only under salt substitutes only under
be sprinkled on food and hypotension, or hepatic stomach
medical supervision medical supervision medical supervision
swallowed without chewing, dysfunction
followed by water
Avoid pregnancy Avoid pregnancy Avoid alcohol, NSAIDS Avoid alcohol Avoid alcohol Avoid grapefruit juice.
 Antihyperlipidemic
Generic simvastatin lovastatin atorvastatin pravastatin rosuvastatin
Brand Zocor Altoprev, Mevacor Lipitor Pravachol Crestor
Therapeutic Antihyperlipidemic Antihyperlipidemic Antihyperlipidemic Antihyperlipidemic Antihyperlipidemic
Tablet Tablet/ER Tablet Tablet Tablet

Dosage forms

Hyperlipidemia Hyperlipidemia Hyperlipidemia Hyperlipidemia

1° or 2° prevention of 1° or 2° prevention of 1° or 2° prevention of
atherosclerotic CV disease Coronary arteriosclerosis atherosclerotic CV disease atherosclerotic CV disease CV Disorder
2° prevention of CV events 2° prevention of CV events
Indications with or at risk for CAD Hypercholesterolemia with or at risk for CAD CV accident prevention hypertriglyceridemia
Familial Familial Familial Familial Familial
hypercholesterolemia hypercholesterolemia hypercholesterolemia hypercholesterolemia hypercholesterolemia
mixed lipidemia

Avoid grapefruit (>1L/day) Avoid grapefruit (>1L/day)

Avoid excessive alcohol Avoid excessive alcohol Avoid excessive alcohol Avoid concurrent heavy alcohol Do not drink alcohol
Report signs/symptoms of
Contact prescriber immediately rhabdomyolysis, jaundice Contact prescriber immediately Contact prescriber immediately
if pregnancy occurs while taking (yellowing of skin or eyes), or if pregnancy occurs while taking if pregnancy occurs while taking
atorvastatin renal failure atorvastatin Contraindicated in pregnancy. atorvastatin
There are multiple significant There are multiple significant
drug-drug interactions with drug-drug interactions with
simvastatin. Consult a health- lovastatin. Consult a health-care
PT Counseling care professional prior to professional prior to starting any
starting any new medications, new prescription or OTC
including OTC and herbal drugs. medications
Does not take the place of Does not take the place of Does not take the place of Does not take the place of Does not take the place of
lifestyle changes (diet, exercise) lifestyle changes (diet, exercise) lifestyle changes (diet, exercise) lifestyle changes (diet, exercise) lifestyle changes (diet, exercise)
to lower cholesterol levels. to lower cholesterol levels. to lower cholesterol levels. to lower cholesterol levels. to lower cholesterol levels.
Swallow extended-release Notify prescriber if unexplained
tablets whole; do not chew, muscle tenderness or weakness
crush, or cut occurs
Immediate-release tablets
should be taken with the
evening meal. Extended-release Take in the evening
tablets should be taken at
bedtime.
 Antihyperlipidemic
Generic Omega 3 acid Ethyl Esters fenofibrate gemfibrozil ezetimibe
Brand Lovaza Lofibra, Tricor Lopid Zetia
Therapeutic Antihyperlipidemic Antihyperlipidemic Antihyperlipidemic Antihyperlipidemic
Tablet Tablet
Liquid filled Capsule Capsule/DR

Hypercholesterolemia,
Coronary arteriosclerosis;
primary
prophylaxis-familial
hypercholesterolemia or
combined hyperlipidemia
mixed dyslipidemia Primary hypercholesterolemia
Familial hypercholesterolemia-
Indications Familial type V
homozygous, with atorvastatin
hyperlipoproteinemia
Hypertriglyceridemia Hypertriglyceridemia or simvastatin
Fredrickson type IV
hyperlipoproteinemia Mixed hyperlipidemia

Fenoglide tablets and Lipofen R

Take with or without food and may
Swallow the whole capsule; take capsules should be given with Take 30 min before breakfast
be taken at the same time as a
with food food; others can be taken and dinner
concurrent statin
without food
report signs/symptoms of In patients receiving a bile acid
Seek medical attention if severe
rhabdomyolysis, jaundice sequestrant concurrently, ezetimibe
rash, chest pain, heart Take 1 h before or 4-6 h after a
PT Counseling palpitations, or shortness of bile acid binding resin
(yellowing of skin or eyes), or should be taken at least 2 h before
renal failure. or 4 h after the bile acid
breath.
sequestrant is taken
Products are not
interchangeable
Do not use if you have severe
kidney disease or liver disease.
 Anticoagulant Antiplatelet
Generic warfarin dabigatran apixaban rivaroxaban enoxaparin prasugrel ticagrelor clopidogrel
Brand Coumadin Pradaxa Eliquis Xarelto Lovenox Effient Brilinta Plavix
Therapeutic Anticoagulant Anticoagulant Anticoagulant Anticoagulant Anticoagulant Antiplatelet Antiplatelet Antiplatelet
Tablet Tablet Tablet Tablet Tablet Tablet
Dosage forms Capsule Prefilled Syringe
Multi-Dose Vial
Atrial fibrillation Acute coronary syndrome
Treatment and prevention of Hip/knee replacement DVT Prophylaxis for: Prevention of Acute ST segment elevation
atrial fibrillation; history of myocardial
initial or recurrent deep Prevention of abdominal surgery thromboembolism after myocardial infarction
myocardial infarction; surgery infarction
venous thrombosis and thromboembolism: hip/knee replacement percutaneous coronary managed medically
prosthetic cardiac valve DVT/PE
pulmonary embolism, > in patients after orthopedic acute medical illness intervention
component embolism; non–ST segment elevation
Indications Also after hip replacement surgery
pulmonary embolism; myocardial infarction
>in patients with nonvalvular
thrombosis, Prevention of stroke and atrial fibrillation Thrombosis prevention in
post myocardial infarction; systemic embolism in patient Acute ST segment elevation
venous thromboembolism arteriosclerotic vascular
with nonvalvular atrial myocardial infarction
disease
fibrillation
Unstable angina and non–Q-
DVT/PE
wave myocardial infarction
Do not take more than 100
Avoid alcohol, cranberry
mg/d of aspirin. Let your
products, and drastic changes in May be given with or without Administer with the evening May be given with or without
Take with or without food healthcare provider know if you
vitamin K consumption from food meal food
have any signs of bleeding or
diet (cruciferous vegetables).
shortness of breath.
Do not stop taking apixaban
Do not stop therapy abruptly Do not stop therapy abruptly
without talking with your . If self-administered (outside
Avoid situations/activities in without first talking with without first talking with
Increased risk of stroke on health-care provider, stopping Doses ≥15 mg should be taken health-care facility), instruct
which cuts, bruising, or injury is prescriber to minimize the risk prescriber to minimize the risk
discontinuation. early may increase the risk of with food. patient on appropriate
likely to occur. of re-thrombosis, particularly of re-thrombosis, particularly
stroke, especially in patients administration technique
after stent placement after stent placement.
with atrial fibrillation
Treatment must be suspended Report signs/symptoms of Report signs/symptoms of
PT Counseling Report signs/symptoms of Seek medical attention if any Warn of risks of epidural (spinal)
Monitor for signs of thrombosis
prior to surgical procedures, bleeding, especially if used bleeding, especially if used
hemorrhage, skin and tissue unexpected bleeding or trouble anesthesia while taking
using protocols provided in the and bleeding complications. concomitantly with concomitantly with
necrosis. breathing. rivaroxaban.
product package insert anticoagulant therapy anticoagulant therapy.
Educate patient on signs and
Many significant drug-drug Apixaban should be interrupted symptoms of bleeding and Ticagrelor should be
Tablet may be crushed, but
interactions, consult health-care 24-48 h prior to dental and interactions with other discontinued 5 d prior to
Do not open capsules. should not be split for purposes
professional prior to new surgical procedures and re- anticoagulant or antiplatelet elective surgery, if an
of dividing doses
prescription or OTC use started after hemostasis medications, including OTC antiplatelet effect is not desired
medications
Avoid OTC NSAIDs and high- Avoid OTC NSAIDs and high-
dose aspirin, they increase the dose aspirin, they increase the
risk of bleeding. risk of bleeding.
 Antidiabetic
Generic metformin sitagliptin glimepiride glipizide pioglitazone
Brand Glucophage Januvia Amaryl Glucotrol Actos
Therapeutic Antidiabetic Antidiabetic Antidiabetic Antidiabetic Antidiabetic
Tablet/ER Tablet Tablet Tablet/ER Tablet

Dosage forms Solution

Diabetes mellitus, type 2 Diabetes mellitus Diabetes mellitus Diabetes mellitus Diabetes mellitus
Indications Polycystic ovary syndrome

Take with morning meal if once-

daily dosing. Take with morning Take with food or milk in the Take 30 min before morning May take without regard to
Take with meals
and evening meal if twice-a-day morning meal food
dosing
When used in combination with
Avoid alcohol; this increases the Do not drink alcohol; may cause Do not drink alcohol; may cause
insulin or sulfonylureas, risk of
risk of lactic acidosis. a disulfiram reaction a disulfiram reaction
hypoglycemia may be increased
Drink plenty of liquids to
PT Counseling Use a sunscreen and avoid Use a sunscreen and avoid
improve elimination of
sunlamps and tanning beds. sunlamps and tanning beds.
metformin
Monitor blood glucose in Monitor blood glucose in
. Monitor blood glucose in
frequent intervals (2-4 times per frequent intervals (2-4 times per
frequent intervals (2-4 times per
day); if <70 mg/dL, eat candy or day); if <70 mg/dL, eat candy or
d)
sugar and contact prescriber sugar and contact prescriber
Do not chew or crush extended- May require several weeks for
release formulation. max effect.
 Antidiabetic
Generic liraglutide Insulin Aspart Insulin Lispro Insulin Detemir Insulin Glargine
Brand Victoza Novolog Humalog Levemir Lantus, Toujeo
Therapeutic Antidiabetic Antidiabetic Antidiabetic Antidiabetic Antidiabetic

Dosage forms Solution: Pen Injector Solution: Pen Injector Solution: Pen Injector Solution: Pen Injector
Injection Solution Injection Solution Injection Solution Injection Solution

Diabetes type 2 Diabetes, type 1 and 2 Diabetes, type 1 and 2 Diabetes, type 1 and 2 Diabetes, type 1 and 2
Indications Chronic weight management

Dispose needles in sharps Dispose needles in sharps Dispose needles in sharps Dispose needles in sharps
container. Do not share needles; container. Do not share needles; container. Do not share needles; container. Do not share needles;
Can be injected without regard
this increases the risk of this increases the risk of this increases the risk of this increases the risk of
to meals
transmission of infectious transmission of infectious transmission of infectious transmission of infectious
diseases. Rotate injection sites. diseases. Rotate injection sites. diseases. Rotate injection sites. diseases. Rotate injection sites.
Administer in upper arm, thigh,
or abdomen. Change needle for Store unopened vials in Store unopened vials in Store unopened vials in Store unopened vials in
each injection, do not share refrigerator. refrigerator. refrigerator. refrigerator.
pens, even if needle is changed.
If also using insulin, administer You may choose to keep open You may choose to keep open You may choose to keep open You may choose to keep open
PT Counseling
with separate injection in a non- vials at room temperature if it is vials at room temperature if it is vials at room temperature if it is vials at room temperature if it is
adjacent area painful to inject cold insulin painful to inject cold insulin painful to inject cold insulin painful to inject cold insulin
Monitor blood glucose
periodically (typically daily, Monitor blood glucose in Monitor blood glucose in Monitor blood glucose in Monitor blood glucose in
more frequently if administered frequent intervals (2-4 times per frequent intervals (2-4 times per frequent intervals (2-4 times per frequent intervals (2-4 times per
with sulfonylurea or insulin). If day); if <70 mg/dL, eat non- day); if <70 mg/dL, eat non- day); if <70 mg/dL, eat non- day); if <70 mg/dL, eat non-
<70 mg/dL eat non-sugar free sugar free candy, glucose sugar free candy, glucose sugar free candy, glucose sugar free candy, glucose
candy, glucose tablets, or drink tablets, or drink a glass of juice tablets, or drink a glass of juice tablets, or drink a glass of juice tablets, or drink a glass of juice
a glass of juice and contact and contact prescriber and contact prescriber and contact prescriber and contact prescriber
prescriber
Not for IV or IM use. Do not
share pens, even if needles are
changed.
 Hormone
Generic levothyroxine thyroid testosterone estradiol conjugated estrogens medroxyprogesterone
Brand Synthroid Armour Thyroid AndroGel, Androderm Estrace Premarin Provera, Depo-Provera
Therapeutic Hormone/Thyroid Hormone/Thyroid Hormone/Androgen Hormone/Estrogen Hormone/Estrogen Hormone/Progestin
Tablet Tablet Tablet Tablet Tablet
Capsule
Dosage forms Transdermal Patch/Cream
Topical Gel
Mucoadhesive for buccal

Secondary physiologic
Hypothyroidism Hypothyroidism Hypogonadism Abnormal vasomotor function Abnormal vasomotor function amenorrhea
Breast cancer, metastatic, for Abnormal uterine bleeding
TSH Suppression palliation only Primary ovarian failure unrelated to menstrual
Prevention cycle
of estrogen-
Thyroid Cancer Atrophic vulva or vagina Atrophic vulva or vagina induced endometrial
Indications Carcinoma of prostate hyperplasia
Decreased estrogen level, Decreased estrogen level,
secondary to hypogonadism, secondary to hypogonadism,
castration, or primary ovarian castration, or primary ovarian
failure failure
Postmenopausal osteoporosis, Postmenopausal osteoporosis,
prophylaxis prophylaxis

Gel to be applied to clean, dry, Menstrual bleeding should

Take on an empty stomach, with intact skin of the shoulders and occur 3-7 d after last dose.
Take on an empty stomach, with Take at bedtime to minimize side
water at least 30 min before upper arms and/or abdomen, Patients should report if
water effects. Take with or without meals.
food. but should not be applied to menstruation does not occur
genitals within 7 d after last dose.
Discuss potential long-term adverse
Gel should be allowed to dry effects of hormone therapy
Report abnormal vaginal bleeding
Avoid antacids and iron within 4 well; swimming and showering including myocardial infarction, Do not use if you become
or signs/symptoms of a
h of dose. should be avoided for 5-6 h stroke, deep vein thrombosis, pregnant.
thromboembolic disorder
after application. pulmonary embolism, and breast
PT Counseling
cancer
Patients should keep application
Do not smoke during therapy, as
May require 6-8 wk for May require 6-8 wk for site covered, as direct skin
this increases the risk of
symptomatic improvement. symptomatic improvement. contact can transfer drug to
thromboembolic events
others
Do not stop using this medicine Virilization has been reported in
suddenly without asking your children who were secondarily
Avoid abrupt discontinuation doctor; may need to slowly exposed to testosterone gel
decrease dose before stopping it (coming in contact with bare
completely skin around gel application site
Male patients should report too
frequent or persistent erections
Female sexual partners of
patients using drug should
report male-like changes
Do not use higher doses than
you have been prescribed, or
combine with other anabolic
steroids, serious adverse effects
can occur
Seek medical attention if chest
pain, shortness of breath, signs
of stroke or behavioral changes.