Vancomycin
GLYCOPEPTIDES CLASS &
AMINOGLYCOSIDE CLASS
Glycopeptides Class Key NCLEX Tips: Aminoglycosides Class
Vancomycin Tobramycin
KEY Words: Gentamicin Cystic Fibrosis
Indication: REPORT Signs of Toxicity
Neomycin
MRSA C DIFF
Given for serious infections like: Ear Damage “Ototoxicity”
MRSA & C Diff in the gut NCLEX TIP - Vertigo (loss of balance) Indication:
NCLEX TIP - Tinnitus (ringing of the ears)
Treat infections in cystic fibrosis
MOA: Kidney Damage “Nephrotoxic”
MOA:
Inhibits cell wall synthesis REPORT / NOTIFY HCP
Creatinine Blocks protein synthesis of the
OVER 1.3 = Bad Kidney
bacteria to STOP bacterial
KEY Words: growth but the NCLEX
BUN Over 20
PEAK & Trough does not focus on this, but
Urine output 30ml/hr rather on the way this drug
Check 15 – 30 minutes BEFORE
“next dose” or “administration”
or LESS = Kidney Distress can HARM THE PATIENT
Draw & review levels
REPORT and HOLD NCLEX
Over 20 = Vancomycin
KEY POINT:
Draw & Review levels
Assess site every 30 minutes for: KEY POINT:
pain, redness & swelling BUN/Creatinine
Very Toxic in combo with
Red mans Syndrome Vancomycin
KEY Words:
Rapid infusion
***Notify HCP of Increas-
Sudden onset of severe: Monitor BP
ing
Infuse SLOWLY at least BUN/Creatinine!
Hypotension
over 60 minutes
Flushing & pruritis “itching” (<10mg/min)
Red rash on face, neck,
chest & extremities Common NCLEX Question
120/80 A patient in sepsis is prescribed
90/60
several antibiotics during their
80/50
hospital stay. What patient teaching
should be included?
(see exhibit for list of meds)
Levofloxacin
Doxycycline
ANAPHYLAXIS Vancomycin
Azithromycin
Hive 1. Avoid direct sun exposure
Wheezing 2. Oral birth control ineffective
IMMEDIATELY 3. Take until symptoms subside
STOP infusion & administer 4. Monitor QT interval
Epinephrine!
5. Suppliment with vitamin B6
E – Edema “Angioedema”
P – Pruritis & Hives 6. Monitor creatinine and BUN
I – Insp. / Exp. “Wheezes”
Notes