ONLINE GUIDANCE

BADLAPUR (W)

BIOLOGY CLASS XII

Class 12 - Biology
Time Allowed: 1 hour and 15 minutes Maximum Marks: 75

1. Which of the following is genetic disease? [1]

a) Klinefelter’s syndrome b) Turner’s syndrome

c) Down’s syndrome d) Patau’s syndrome

2. In somatic cells of human beings chromosomes exists as: [1]

a) Haploid b) Heterologous pairs

c) Single circular chromosome d) Homologous pairs

3. The given karyotype represents: [1]

a) Down’s syndrome b) Klinefelter’s syndrome

c) Turner’s syndrome d) Normal man

4. Which is a dominant trait? [1]

a) Albinism b) Rh factor

c) Haemophilia d) Colour blindness

5. Which one of the following cannot be explained on the basis of Mendel’s Law of Dominance? [1]

a) Alleles do not show any blending and both b) The discrete unit controlling a particular
the characters recover as such in the F2 character is called a factor
generation

c) Factors occur in pairs d) Out of one pair of factors one is dominant

and the other recessive
6. If a part of chromosome gets detached and lost during the cell division, the mutation so produced is called: [1]

a) Inversion b) Transcription

c) Deletion d) Euploidy
7. Grain colour in wheat is determined by three pairs of polygenes. Following the cross AABBCC (dark colour) × [1]
aabbcc (light colour), in F2 generation what proportion of the progeny is likely to resemble either parent?

a) Less than 5 percent b) None of these

1 / 11
 c) One third d) Half
8. How many types of genotypes are formed in F2 progeny obtained from self-pollination of a dihybrid F1? [1]

a) 3 b) 9

c) 1 d) 6
9. Which of the following condition will form intersex Drosophila? [1]

a) Two sets of autosomes and two A- b) Three sets of autosomes and one A-
chromosomes chromosome

c) Three sets of autosomes and two A- d) Two sets of autosomes and three A-
chromosomes chromosomes
10. Statement I: The bridge between one generation and the next are sperm and ovum. [1]
Statement II: Both sperm and ovum contribute equally to heredity.
Statement III: Somatic diploid cells possess two chromosomes as well as two mendelian factors of each type.

a) All three statements are incorrect b) All three statements are correct

c) Only statement I and II are correct d) Only statement II and III are correct
11. Multiple genes are involved in the inheritance of: [1]

a) Phenylketonuria b) Colourblindness

c) Sickle-cell anaemia d) Skin colour

12. In monohybrid cross what is the ratio of homozygous dominant and homozygous recessive individuals in F2 [1]
generation?

a) 2 : 1/1 : 2 b) 3 : 1/1 : 3

c) 1 : 2 : 1 d) 1 : 1
13. Two genes R and Y are located very close on the chromosomal linkage map of the maize plants. When RRYY [1]
and rryy genotypes are hybridized, the F2 segregation will show:

a) Segregation in 3:1 ratio b) A higher number of parental types

c) A higher number of the recombinant types d) Segregation in the expected 9:3:3:1 ratio
14. The inheritance pattern of a gene over generations among humans is studied by the pedigree analysis. Character [1]
studied in the pedigree analysis is equivalent to:

a) Maternal trait b) Quantitative trait

c) Polygenic trait d) Mendelian trait

15. The given pedigree chart shows the inheritance of which of the following mendelian disorder? [1]

A. Sex linked dominant trait

B. Autosomal dominant trait
C. Sex linked recessive trait

2 / 11
 D. Autosomal recessive trait

a) (D) b) (C)

c) (A) d) (B)
16. In Drosophila the AXY condition leads to femaleness whereas in human beings the same condition leads to [1]
Klinefelter’s syndrome in male. It proves:

a) In human beings Y chromosome is active in b) In Drosophila Y chromosome decides

sex determination femaleness

c) Y chromosome is active in sex d) Y chromosome of man has genes for

determination in both human beings and syndrome
Drosophila
17. In our society, female are blamed for producing female children due to: [1]

a) Scientific reasons b) False notation

c) Production of the same kind of gametes d) Biological concepts

18. Amino acid substituted in sickle-cell anaemia is: [1]

a) Valine for glutamic acid in alpha chain b) Valine for glutamic acid in beta chain

c) Glutamic acid for valine in beta chain d) Glutamic acid for valine in alpha chain
19. Select the incorrect statement. [1]
i. Male fruit fly is heterogametic.
ii. In male grasshoppers, 50% of sperms have no sex-chromosome.
iii. In domesticated fowls, sex of progeny depends on the type of sperm rather than the egg.
iv. Human males have one of their sex-chromosome much shorter than the other.

a) Option (i) b) Option (iii)

c) Option (iv) d) Option (ii)

20. A normal visioned man whose father was colour blind, marries a woman whose father was also colour blind. [1]
They have their first child as a daughter. What are the chance that this child would be colour blind?

a) 25 % b) 100%

c) 50 % d) zero per cent

21. A heterogamous tall plant produces tall and dwarf plants after selflng. This conforms the Mendel’s law called as: [1]

a) Law of dominance b) Law of purity of gametes

c) Law of segregation d) Law of independent assortment

22. Choose the right sequence from table: [1]

S. No. Syndrome Genotype Bar body

(A) Turner syndrome 44 + XO 1

(B) Criminal syndrome 44 + XYY 0

(C) Klinefelter syndrome 44 + XXY 1

(D) Cri-du-chat syndrome 44 + XXX 2

3 / 11
 Find out the correct statements of above table:

a) B, C b) A, B

c) C, D d) A, D

23. The genotypes of a husband and wife are IAIB and IAi. Among the blood types of their children, how many [1]

different genotypes and phenotypes are possible?

a) 3 genotypes : 4 phenotypes b) 4 genotypes : 3 phenotypes

c) 4 genotypes : 4 phenotypes d) 3 genotypes : 3 phenotypes

24. In Mendelian genetics one of the following characters is the dominant: [1]

a) Green colour of seeds b) Green colour of pods

c) Wrinkled seeds d) Terminal flowers

25. Henking X-body present in 50% of sperms is now known as: [1]

a) Lamp brush chromosomes b) Autosomes

c) Y-chromosome d) X-chromosome
26. Haemophilia is: [1]

a) Autosomal sex linked disorder b) T-linked

c) Deficiency disorder d) Sex linked disorder

27. If a genetic disease is transferred from a phenotypically normal but carrier female to only some of the male [1]
progeny, the disease is:

a) Autosomal recessive b) Sex-linked recessive

c) Sex-linked dominant d) Autosomal dominant

28. Dihybrid cross proves the law of: [1]

a) Purity of gametes and genes b) Segregation of gene

c) Dominance of gene d) Independent assortment

29. Person having genotype IAIB would show the blood group as AB. This is because of: [1]

a) Incomplete dominance b) Pleiotropy

c) Segregation d) Co-dominance
30. If a colourblind woman marries with a normal man, the offspring will be: [1]

a) All daughters normal and all son will be b) All normal

colourblind

c) All daughters will be colourblind and all d) All colourblind

sons will be normal
31. Segregation of homologous chromosomes occurs during: [1]

a) Gametes formation b) During gene expression

c) During mitosis division d) During equational division

32. On the basis of the sex chromosome shown below, the bird shown is [1]

4 / 11
 a) Female b) Cannot be decided

c) Transgender d) Male
33. A colourblind girl will always have colourblind: [1]

a) Mother b) Brother

c) Father d) Sister
34. In Antirrhinum (Snapdragon), a red flower was crossed with a white flower and in F1 generation, pink flowers [1]

were obtained. When pink flowers were selfed, the F2 generation showed white, red and pink flowers. Choose

the incorrect statement from the following:

a) This experiment does not follow the b) Ratio of F2 is 1

4
(Red): 2

4
(Pink): 1

Principle of Dominance. (White).

c) Pink colour in F1 is due to incomplete d) Law of Segregation does not apply in this
dominance. experiment.

35. What map unit (Centimorgan) is adopted in the construction of genetic maps? [1]

a) A unit of distance between genes on b) A unit of distance between two expressed

chromosomes, representing 1% cross over. genes, representing 100% cross over.

c) A unit of distance between two expressed d) A unit of distance between genes on

genes, representing 10% cross over. chromosomes, representing 50% cross over.
36. “Gametes are never hybrid”. This is a statement of [1]

a) Law of segregation b) Law of random fertilisation

c) Law of dominance d) Law of independent assortment

37. Which of the following causes point mutation? [1]

a) Inversion b) Deletion

c) Transition d) All of these

38. Albinism is a: [1]

a) Hereditary disease b) Deficiency disease

c) Sex-linked disease d) Contagious disease

39. In human males, some recessive genes express their effect because: [1]

a) Only two sex chromosome b) Only one Y-chromosome

c) Single genome d) Only one X-chromosome

40. The pairs of chromosomes present in human beings somatic cells are: [1]

a) 45 b) 46

5 / 11
 c) 22 d) 23
41. Test cross is: [1]

a) TT × TT b) Tt × Tt

c) Tt × tt d) Tt × TT
42. On crossing red and white flowered plants the ratio of red and white flowered plants in F2-generation was 60 : [1]

20, then on selfing the heterozygous red flowered plants, the offsprings would be:

a) 52 : 48 b) 84 : 16

c) 40 : 60 d) 72 : 24
43. Alleles are: [1]

a) True breeding homozygotes b) Different phenotype

c) Heterozygotes d) Different molecular forms of a gene

44. Mendel enunciated how many principles of inheritance? [1]

a) Three b) One

c) Two d) Four
45. Given below is a pedigree chart with symbols for sex-linked trait in humans. The trait of the above pedigree [1]
chart is:

a) Dominant X-linked b) Recessive X-linked

c) Recessive Y-linked d) Dominant Y-linked

46. Dihybrid test cross ratio proposed by Mendel is: [1]

a) 1 : 1 : 1 : 1 b) 1 : 2 : 2 : 4 : 1 : 2 : 1 : 2 : 1

c) 3 : 1 d) 9 : 3 : 3 : 1
47. Which of the following most appropriately describes haemophilia? [1]

a) Recessive gene disorder b) Dominant gene disorder

c) X-linked recessive gene disorder d) Chromosomal disorder

48. How many pairs of contrasting characters were chosen by Mendel for his publication of study with garden pea? [1]

a) 7 b) 3

c) 14 d) 5
49. Choose the right sequence from the table: [1]

(A) Inhibitory gene ratio (1) 1.9: 3: 4

(B) Complementary gene ratio (2) 1: 1: 1: 1

6 / 11
 (C) Recessive epistatic ratio (3) 12: 3: 1

(D) Dihybrid test-cross ratio (4) 13: 3

(E) Dominant epistasis ratio (5) 9: 7

a) A-2, B-l, C-4, D-5, E-3 b) A-4, B-5, C-l, D-2, E-3

c) A-l, B-2, C-4, D-3, E-5 d) A-5, B-4, C-3, D-2, E-1

50. 1. Shows tall stature with ferminised characters (gynaecomastia). [1]

2. Shows short stature, sterility, underdeveloped feminine characters, and webbed neck
3. Shows short-statured, small head, furrowed tongue, creased broad palm, retarded physical, psychomotor, and
mental development.
Identify the syndromes:

a) 1-Tumer’s syndrome, 2-Klinefelter b) 1-Down’s syndrome, 2-Klinefelter

syndrome, 3-Down’s syndrome syndrome, 3-Tumer’s syndrome

c) 1-Klinefelter syndrome, 2-Down’s d) 1-Klinefelter syndrome, 2-Tumer’s

syndrome, 3-Tumer’s syndrome syndrome, 3-Down’s syndrome
51. Test cross in plants or in Drosophila involves crossing: [1]

a) Between two genotypes with recessive trait b) The F1 hybrid with a double recessive

genotype

c) Between two genotypes with dominant trait d) Between two F1 hybrids

52. Barr body is observed in: [1]

a) Basophils of male b) Neutrophils of female

c) Basophils of female d) Eosinophils of female

53. A family has five girls and no son, the probability of the occurrence of son in 6th child is: [1]

a) 1

5
b) No chance

c) 1 d)
1

54. A disease caused by an autosomal primary non-disjunction is : [1]

a) Sickle cell anaemia b) Klinefelter’s syndrome

c) Turner’s syndrome d) Down’s syndrome

55. An organism with two identical alleles is: [1]

a) Dominant b) Hybrid

c) Homozygous d) Heterozygous
56. When a tall plant with round seeds (TTRR) is crossed with a dwarf plant with wrinkled seeds (ttrr), the F1 [1]
generation consists of tall plants with rounded seeds. How many types of gametes F1 plant would produce?

a) Eight b) One

c) Three d) Four
57. In case of co-dominance, the offsprings of F1 generation have the trait: [1]

7 / 11
 a) Of either of two parents b) Of both the parents

c) Of none of the parents d) Of only dominant parent

58. In a monohybrid cross the genotypic ratio of the offspring in F2 generation is: [1]

a) 1 : 1 : 1 : 1 b) 3 : 1

c) 4 : 0 d) 1 : 2 : 1
59. Study the pedigree chart of a certain family given below and select the correct conclusion which can be drawn [1]
for the character

a) The trait under study could not be colour b) The female parent is heterozygous
blindness

c) The male parent is homozygous dominant d) The parent could not have had a normal
daughter for this character
60. Assertion (A): The cross between red and white flower bearing snapdragon plants results in a pink coloured [1]
flower.
Reason (R): Incomplete dominance of red and white flower results into pink coloured flower.

a) Both A and R are true and R is the correct b) Both A and R are true but R is not the
explanation of A. correct explanation of A.

c) A is true but R is false. d) A is false but R is true.

61. Assertion (A): Hybrids are generally superior than their parents. [1]
Reason (R): All the dominant traits are present in the hybrid.

a) Both A and R are true and R is the correct b) Both A and R are true but R is not the
explanation of A. correct explanation of A.

c) A is true but R is false. d) A is false but R is true.

62. Assertion (A): In humans, a normal female has sex chromosomes (XX) and the male has sex chromosomes as [1]
(X Y ).
Reason (R): In chicken, sex chromosomes in the male are ZZ, and in females are ZW.

a) Both A and R are true and R is the correct b) Both A and R are true but R is not the
explanation of A. correct explanation of A.

c) A is true but R is false. d) A is false but R is true.

63. Assertion (A): The principle of segregation given by Mendel is the principle of purity of gametes. [1]
Reason (R): Gametes are pure for a character.

a) Both A and R are true and R is the correct b) Both A and R are true but R is not the
explanation of A. correct explanation of A.

c) A is true but R is false. d) A is false but R is true.

64. Assertion (A): Most insects including fruit fly Drosophila and mammals including human beings the females [1]

8 / 11
 possess two homomorphic sex chromosomes, named XX.
Reason (R): Parents are homogametry.

a) Both A and R are true and R is the correct b) Both A and R are true but R is not the
explanation of A. correct explanation of A.

c) A is true but R is false. d) A is false but R is true.

65. Assertion (A): Not all characters shows true dominance. [1]
Reason (R): Some characters shows incomplete and some shows co-dominance.

a) Both A and R are true and R is the correct b) Both A and R are true but R is not the
explanation of A. correct explanation of A.

c) A is true but R is false. d) A is false but R is true.

66. Assertion (A): Turner’s syndrome is caused due to the absence of one X chromosomes. [1]
Reason (R): The female suffering from the turner’s syndrome is sterile as ovaries are rudimentary along with
other secondary sexual characters.

a) Both A and R are true and R is the correct b) Both A and R are true but R is not the
explanation of A. correct explanation of A.

c) A is true but R is false. d) A is false but R is true.

67. Assertion (A): An organism with a lethal mutation may not even develop beyond the zygote stage. [1]
Reason (R): All types of gene mutations are lethal.

a) Both A and R are true and R is the correct b) Both A and R are true but R is not the
explanation of A. correct explanation of A.

c) A is true but R is false. d) A is false but R is true.

68. Assertion (A): Beri-beri can be studied by pedigree analysis. [1]
Reason (R): Non heritable and inheritable characters or disease can be studied by generating a pedigree of a
family.

a) Both A and R are true and R is the correct b) Both A and R are true but R is not the
explanation of A. correct explanation of A.

c) A is true but R is false. d) A is false but R is true.

69. Assertion (A): A recessive character that was not expressed in heterozygous condition may be expressed again [1]
when it becomes homozygous.
Reason (R): The characters never blend in heterozygous condition.

a) Both A and R are true and R is the correct b) Both A and R are true but R is not the
explanation of A. correct explanation of A.

c) A is true but R is false. d) A is false but R is true.

70. A man and a woman, who do not show any apparent signs of a certain inherited disease, have seven children (2 [2]
daughters and 5 sons). Three of the sons suffer from the given disease but none of the daughters are affected.
Which of the following mode of inheritance do you suggest for this disease?

a) Sex-linked dominant b) Autosomal dominant

c) Sex-linked recessive d) Sex-limited recessive

9 / 11
71. Read the following and answer any four questions: [4]
Haemophilia is a sex linked disease which is also known as bleeders disease as the patient will continue to bleed
even from a minor cut since he or she does not possess the natural phenomenon of blood clotting due to absence
of anti-haemophilic globulin or factor VIII and plasma thromboplastin factor IX essential for it. As a result of
continuous bleeding the patient may die of blood loss. Colour blindness is another type of sex linked trait in
which the eye fails to distinguish red and green colours. Vision is however, not affected and the colour blind can,
lead a normal life, reading, writing and driving (distinguishing traffic lights by their position).
i. If a haemophilic man marries a woman whose father was haemophilic and mother was normal then which of
the following holds true for their progenies?
a. Of the total number of daughters, 50% daughters are carrier and 50% are haemophilic.
b. All the daughters are haemophilic.
c. All sons are haemophilic and all daughters are normal.
d. All sons are normal, all daughters are carriers.
ii. A man whose father was colourblind and mother was normal marries a woman whose father was
haemophilic and mother was normal. Which of the following is true for their progenies? [Note: Percentage is
from the total number of progenies.]
a. 25% female progenies carry the gene for both haemophilia and colourblindness.
b. 25% male progenies carry only the gene of colourblindness.
c. 25% female progenies carry only the gene of colourblindness.
d. 25% male progenies and 25% female progenies carry the gene of haemophilia.
iii. Which of the following statements is incorrect regarding haemophilia?
a. It is a dominant disease.
b. A single protein involved in clotting of blood is affected.
c. It is recessive disease.
d. It is Mendelian disorder.
iv. Anup is having colourblindness and is married to Soni who is normal. What is the chance that their son will
have the disease?
a. 100%
b. 50%
c. 25%
d. 0%
v. Refer to the given cross.

Select the correct option regarding 1, 2, 3 and 4.

a. 1. Colourblind carrier female
2. Colourblind haemophilic female

10 / 11
 3. Normal male
4. Haemophilic male
b. 1. Colourblind people
2. Haemophilic female
3. Normal male
4. Haemophilic male
c. 1. Colourblind female
2. Colourblind and haemophilic female
3. Normal male
4. Normal male
d. 1. Colourblind carrier female
2. Normal female
3. Normal male
4. Haemophilic male
vi. Which of the following statement is incorrect?
I. In haemophilia single protein that is a part of the cascade of proteins involved in the clotting of blood is
affected.
II. Haemophilia is an autosomal linked recessive disease.
III. Colour blindness defect is due to mutation in certain genes present in the Y chromosome. IV. Colour
Blindness is a sex-linked recessive disorder.
a. I and II
b. III and II
c. III and IV
d. I and IV

11 / 11