Name: Fathy Ezzat Fathy Abdel-Awad
Group: A6
Livagoal (Silymarin) Overview
Mechanism of Action of Livagoal
Livagoal (Silymarin) is a flavonoid complex derived from milk thistle. It has
hepatoprotective properties and works by stabilizing hepatocyte membranes, reducing
oxidative stress, and enhancing liver regeneration.
- Acts as an antioxidant, neutralizing free radicals that damage liver cells.
- Enhances protein synthesis in hepatocytes, promoting liver tissue regeneration.
- Inhibits inflammatory pathways, reducing liver inflammation and fibrosis.
Livagoal is commonly used for liver protection in cases of hepatitis, cirrhosis, and toxic liver
damage.
Side Effects of Livagoal
Common Side Effects:
- Nausea
- Diarrhea
- Abdominal bloating
- Allergic reactions (rash, itching)
Serious Side Effects:
- Severe allergic reactions (swelling, difficulty breathing)
- Gastrointestinal disturbances in high doses
Nursing Role for Side Effects
- Monitor for allergic reactions and educate patients to report any signs of swelling or
difficulty breathing.
- Advise patients to take the medication with food to reduce gastrointestinal side effects.
- Encourage proper hydration to manage mild diarrhea.
- Monitor liver function tests periodically to assess efficacy and safety.
Visceralgine (Tiemonium Methylsulfate) Overview
Mechanism of Action of Visceralgine
Visceralgine (Tiemonium Methylsulfate) is an antispasmodic drug that works by blocking
muscarinic receptors, leading to relaxation of smooth muscles in the gastrointestinal and
urinary tract.
- Reduces spasms by inhibiting parasympathetic nerve stimulation on smooth muscle.
- Relieves pain caused by visceral muscle contractions in conditions like irritable bowel
syndrome and renal colic.
Visceralgine is commonly used to treat abdominal cramps, biliary colic, and painful bladder
spasms.
Side Effects of Visceralgine
Common Side Effects:
- Dry mouth
- Blurred vision
- Dizziness
- Constipation
Serious Side Effects:
- Urinary retention
- Increased intraocular pressure (caution in glaucoma patients)
- Tachycardia or palpitations
Nursing Role for Side Effects
- Educate patients on the risk of dry mouth and advise increased fluid intake.
- Monitor for signs of urinary retention, especially in elderly patients.
- Caution in patients with glaucoma due to the risk of increased intraocular pressure.
- Assess for cardiovascular side effects like palpitations and tachycardia.
- Advise patients to avoid driving if they experience dizziness or blurred vision.