AUTUMN SCHOOL PACESETTER LIFE SCIENCES GRADE 12 2025
DURATION 10 Hrs FOCUS TOPIC: GENETICS- P 2 TOPIC EXAMINED FOR 48MARKS.
RESOURCES JENN GENETICS CONTENT MANUAL
2021 EXAMINATION GUIDELINES
PAST NSC EXAMINATION PAPERS
DBE VIRTUAL WORKSHOP VIDEO
CHIEF MARKERS & DIAGNOSTIC REPORT
EMPHASIS
• Difference between gene & allele
• 2 alleles controlling a characteristic, one allele inherited from mother, other
allele inherited from the father
• In monohybrid cross- Genotype of parent before meiosis has 2 alleles for a
particular characteristic (diploid somatic cell) whilst the gametes of the parent
have 1 allele for that characteristic (haploid)
• Stress Law of dominance and Law of segregation according to examination
guidelines
• The correct format of genetic cross must be practised by all learners
• Stick to phenotype descriptions given in the question, learners should not use
their own words to describe a phenotype
• Be clear about difference in in complete dominance, complete dominance,
and codominance
• How inheritance of blood groups relates to codominance and complete
dominance
• Practice calculations based on phenotype / genotype ratios
• Confusing autosomal and sex-linked inheritance when interpreting a pedigree
diagram
DAY TEACHER ACTIVITY LEARNER ACTIVITY TIME
1
Invigilator Pre-test 30
min
- Genetics terminology explained 1,5
through diagrams and simplified in Homework hrs
words Activity 1 - 3 pg.10
Pg. 7 – 9
- Genetics and sexual reproduction
Pg. 11
2
Feeback for Homework Mark homework 10
min
- Monohybrid cross definition & format 50
for genetic cross using inheritance min
of eye colour (B – brown, b for blue) Classwork
Pg. 12-13 Activity 4 pg 16
- Teacher does example on the board
1)Homozygous brown eyes X blue
eyes 2)Homozygous brown eyes X Classwork (5min)
heterozygous brown Cross Heterozygous brown eyes x
blue eyes
- State Mendel’s Principle of
segregation as stated in pg 12 of
2021 examination guidelines) Ensure
all learners can do genetic cross-
identify struggling learners for further
assistance (maybe through using
different colours to represent lines or
using punnet square
- Types of dominance Classwork 1hr
State law of dominance when Activity 5 pg 16
teaching complete dominance (pg 11
of 2021 Examination Guidelines)
Pg.14-15 Homework
Activity 6 - 7 pg17-18
- Monohybrid cross with incomplete
dominance Classwork
Pg. 18-19 Activity 8
Pg 19
- Monohybrid cross with co-
dominance Homework
Pg. 19 - 20 Activity 9
Pg 21
3
Feedback for Homework Mark homework 10min
- Blood groups as an example of Classwork 50
Co-dominance Activity 10 min
Pg. 21 - 22 Pg. 22
Explain inheritance of blood
groups using table showing
phenotypes and possible
genotypes.
- Why Blood type inheritance is
controlled by multiple alleles
- Stress the difference between
genotype and alleles for blood
group
Classwork / Homework
- Explain how blood groups may be
Activity 11
used to determine paternity using
Pg. 22
marking guide for 2019 Nov paper 2
- Sex determination in humans 1 hr
Pg. 23 – 24
Explain karyotypes using diagram on
pg 23
Explain Sex determination using the
genetic problem on page 24 and the
marking guideline for November
2019 essay question
- Sex-linked inheritance Classwork & Homework
Pg. 24 - 26
Explain What is sex linked inheritance Activity 12
- Use haemophilia and colour- Pg 27
blindness to explain inheritance of
sex linked diseases.
- Explain why sex linked disorder
mostly affects males Homework
Explain why sex linked disorder Activity 13 - 16
affects fewer females Pg 27 – 28
4
- Feedback for homework Mark homework 10min
- Genetic Lineage/Pedigree
Pg. 29 - 31 Classwork 1 hrs
Define a pedigree diagram 50 min
Activity 17
- Interpretation of pedigree diagrams
Pg. 31
- Use a pedigree diagram to solve
inheritance that is not sex linked-
autosomal page 21
- Use a pedigree diagram for sex
linked inheritance
- NB XX for female and XY for male
with an allele on top of X
chromosome. APPLIES TO SEX Homework
LINKED INHERITANCE because Activity 18
gonosomes are for sex Pg. 32
determination
5
- Post Test 1 hr
Complete any work not covered 1 hr
Review misconceptions from test
Practice worksheet of mixed Genetic
Crosses
(To be developed)