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The document contains a series of multiple-choice questions related to hyperlipidemia and lipid-lowering medications, focusing on risk factors, drug safety, effectiveness, and contraindications. Key topics include the safest drug classes for pregnant patients, the most effective treatments for familial hypercholesterolemia, and monitoring requirements for specific medications. It also addresses side effects and interactions associated with various lipid-lowering agents.

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Karan Praba
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5 views3 pages

3

The document contains a series of multiple-choice questions related to hyperlipidemia and lipid-lowering medications, focusing on risk factors, drug safety, effectiveness, and contraindications. Key topics include the safest drug classes for pregnant patients, the most effective treatments for familial hypercholesterolemia, and monitoring requirements for specific medications. It also addresses side effects and interactions associated with various lipid-lowering agents.

Uploaded by

Karan Praba
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
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41.

The primary risk factor for hyperlipidemia is:


A) Smoking
B) Sedentary lifestyle
C) Obesity
D) All of the above

42. Which lipid-lowering drug is safest in pregnancy?


A) Statins
B) Bile acid sequestrants
C) Fibrates
D) Niacin

43. Which drug class is MOST effective for familial hypercholesterolemia?


A) PCSK9 inhibitors
B) Fibrates
C) Niacin
D) Omega-3 fatty acids

44. A patient with a history of gallstones should avoid:


A) Fibrates
B) Statins
C) Ezetimibe
D) Omega-3 fatty acids

45. A 40-year-old woman with peptic ulcer disease should avoid:


A) Statins
B) Niacin
C) PCSK9 inhibitors
D) Omega-3 fatty acids

46. Which lipid-lowering agent is MOST effective in raising HDL cholesterol?


A) Niacin
B) Statins
C) Fibrates
D) Ezetimibe

47. Which drug should be taken at night for maximum effectiveness?


A) Pravastatin
B) Lovastatin
C) Atorvastatin
D) Rosuvastatin

48. Which of the following lipid-lowering agents does NOT lower triglycerides?
A) Statins
B) PCSK9 inhibitors
C) Fibrates
D) Omega-3 fatty acids

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49. Which drug class requires monitoring of liver function tests?
A) Statins
B) Bile acid sequestrants
C) Omega-3 fatty acids
D) PCSK9 inhibitors

50. What is the MOST serious side effect of statins?


A) Rhabdomyolysis
B) Constipation
C) Flushing
D) Hypertension

51. Statins should be used with caution in patients taking:


A) Warfarin
B) Clarithromycin
C) Metformin
D) Lisinopril

51. Which of the following drugs increases the risk of statin-induced myopathy?
A) Amlodipine
B) Erythromycin
C) Metformin
D) Aspirin

52. A 60-year-old woman on statins complains of muscle pain and weakness. What should be checked?
A) Creatine kinase (CK)
B) Serum sodium
C) Hemoglobin
D) White blood cell count

53. Which of the following lipid-lowering drugs is associated with an increased risk of gallstones?
A) Statins
B) Fibrates
C) PCSK9 inhibitors
D) Ezetimibe

54. The MOST serious side effect of fibrates when combined with statins is:
A) Hepatotoxicity
B) Rhabdomyolysis
C) Hypertension
D) Bradycardia

56. Which drug class can impair the absorption of fat-soluble vitamins (A, D, E, K)?
A) Statins
B) Fibrates
C) Bile acid sequestrants
D) PCSK9 inhibitors

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57. Which of the following should be monitored in patients on bile acid sequestrants?
A) Serum potassium
B) Vitamin D levels
C) Liver function tests
D) Blood glucose

58. Bile acid sequestrants are contraindicated in:


A) Complete biliary obstruction
B) Hypercholesterolemia
C) Type 2 diabetes
D) Hypertension

59. PCSK9 inhibitors are mainly used for:


A) Lowering triglycerides
B) Reducing LDL cholesterol
C) Increasing bile acid synthesis
D) Enhancing HDL cholesterol

60. Which patient would benefit MOST from a PCSK9 inhibitor?


A) A 30-year-old with low HDL
B) A 45-year-old with mild hypertriglyceridemia
C) A 55-year-old with familial hypercholesterolemia
D) A 60-year-old with gallstones

61. What is the primary route of administration for PCSK9 inhibitors?


A) Oral
B) Subcutaneous injection
C) Intravenous infusion
D) Transdermal patch

62. Which of the following is a potential drawback of PCSK9 inhibitors?


A) High cost
B) Severe muscle pain
C) Poor absorption
D) Liver toxicity

63. Niacin reduces cholesterol by:


A) Blocking cholesterol synthesis
B) Reducing free fatty acid mobilization
C) Enhancing bile acid reabsorption
D) Increasing triglyceride uptake

64. A major contraindication for niacin use is:


A) Peptic ulcer disease
B) Hypertriglyceridemia
C) Hypothyroidism
D) Low HDL cholesterol

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