Scribd
Upload
38 views2 pages

Chapter 3 Oral Comprehension

The document outlines the importance of oral comprehension in communication and foreign language acquisition, particularly in the context of a scientific English course. It focuses on CAR T-cell therapy, explaining its mechanism, differences from normal T cells, and the process of creating CAR T cells. The content emphasizes the role of T cells in the immune system and their ability to target cancer cells.

Uploaded by

mahammedi salah
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
38 views2 pages

Chapter 3 Oral Comprehension

The document outlines the importance of oral comprehension in communication and foreign language acquisition, particularly in the context of a scientific English course. It focuses on CAR T-cell therapy, explaining its mechanism, differences from normal T cells, and the process of creating CAR T cells. The content emphasizes the role of T cells in the immune system and their ability to target cancer cells.

Uploaded by

mahammedi salah
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
You are on page 1/ 2

Scientific English courses Responsible : RAHMOUNE.

H 2024/2025 L3 /IMC

Chapter 03: English oral comprehension

What is oral comprehension?


 Oral comprehension is one of the most fundamental stages in
communication and in the acquisition of a foreign language;

 Understanding spoken language, such as conversations, stories, and


informational texts, is known as listening comprehension. This involves
extracting and constructing meaning from the spoken words;

 Listening comprehension and oral communication are intertwined. While


listening comprehension is the process of understanding and interpreting
spoken language, oral communication is the process of conveying
information through spoken language;

 In oral communication, information is given, received or transferred


between two individuals.

So, you are going to listen to a video about cancer immunotherapy: CAR T- cell therapy
explained.
Listen carefully. Take notes if you wish. You will then have to answer the questions bellow.

1. What is CAR T- Cell therapy?


- CAR T- Cell therapy is a strategy that has been developed as an individual treatment against
cancer by reprogramming T Cells to express artificially a chimeric antigen receptor or CAR to
fight cancer cells.
- CAR T-cell therapy is used as a treatment option against cancer cells.

2. What are the target cells that can be eliminated by T lymphocytes?


Virus-infected cells and tumor/ cancer cells

1
Scientific English courses Responsible : RAHMOUNE. H 2024/2025 L3 /IMC

3. What is the difference between CAR T cells and normal T cells?


The only characteristic that makes car t cells different from natural t cells is the chimeric antigen
receptor.

4. How are CAR T cells made?

- Step 1: Blood is removed from the patient and the T cells are isolated and cultured
- Step 2: Involves the genetic modification, using a virus vector such as the lentivirus which
carries the genetic information that encodes for the chimeric antigen receptor and this process
called viral transduction after the t cell infection, the car gene is inserted then the protein
receptor is produced after transcription and translation.

Step 3: The CAR T cell population is expanded in the lab and then finally infused back into the
patient,

The CAR T cells can ( patrol) control the whole body, recognize tumor cells with the distinct
antigen such as CD19 and eliminate the cancer cells by different mode of action such as release
of cytokines, perforin/ ganzyme and Fas/ Fas Ligand.

5. T cells are an important pillar of the human immune system (pilier)

6. CAR T cells possess normal T cell receptors and they expressed artificially
chimeric T cell receptors

You might also like