PHINMA University of Pangasinan
College of Health Sciences
Name of Student Nurse: Trisha Neil M. Vergel de Dios Date: 10/10/24
Level/block/group: 2BSN-25 Hospital/Area: RHU Calasiao Clinical Instructor: Iane Morales
NAME OF DRUG MECHANISM OF ACTION CONTRAINDICATIONS SIDE EFFECTS ADVERSE EFFECTS NURSING RESPONSIBILITIES
GENERIC NAME • Nicorandil has a dual mechanism that • Hypotension: • Common Side Effects: • Cardiovascular: Nursing Responsibilities
Nicorandil combines potassium channel activation Nicorandil can cause a
and nitrate-like vasodilation. It dilates significant drop in blood •Headaches Hypotension Pre-Administration:
the coronary arteries, which increases pressure, so it should be
BRAND NAME blood flow to the heart, improving used cautiously in •Feeling dizzy or weak Tachycardia 1. Patient Assessment:
oxygen delivery. At the same time, by patients with already Flushing
Dancor, Ikorel
opening potassium channels, it relaxes low blood pressure. •Feeling or being sick Cardiovascular Evaluation: Check the
the smooth muscles in blood vessels, (nausea or vomiting) patient’s baseline blood pressure and
reducing both the preload and afterload • Concurrent use of heart rate. Nicorandil can cause
on the heart, ultimately lowering PDE5 inhibitors (e.g., •Flushing • Gastrointestinal: hypotension, so it’s important to
CLASSIFICATION myocardial oxygen demand. sildenafil): The establish baseline vitals.
• Drug Class: Potassium combination can cause Oral ulcers
channel activator with dangerous drops in Review Current Medications: Assess
nitrate-like properties blood pressure. Nausea for the use of other vasodilators,
especially PDE5 inhibitors like
• Severe kidney or liver Vomiting sildenafil, which could dangerously
INDICATION disease: Use with potentiate the hypotensive effects of
• Angina Pectoris caution in these Nicorandil.
(Stable Angina): patients as the drug's
Nicorandil is primarily metabolism may be • Neurological: History of Ulcers: Nicorandil is known
prescribed for the affected. to cause ulcers (oral or
treatment and Headaches gastrointestinal), so it’s important to
prevention of angina assess if the patient has a history of
pectoris in patients with Dizziness these conditions.
coronary artery disease.
It helps reduce the
frequency and severity
of anginal attacks by 2. Patient Education:
improving blood flow to
the heart muscles and Explain that headaches are a common
reducing oxygen side effect, especially when starting
demand. treatment, and often subside with
time. Advise patients to take
• Off-Label Uses: analgesics like paracetamol if needed.
It is occasionally used in
certain cases of Inform them that they should rise
unstable angina or slowly from sitting or lying positions to
heart failure where prevent dizziness or fainting due to
other treatments have drops in blood pressure.
been inadequate or
poorly tolerated. Instruct patients on how to recognize
Nicorandil’s dual action early signs of ulcers, such as mouth
on both arteries and sores or stomach pain, and encourage
veins makes it a them to report these symptoms
versatile option in immediately.
managing ischemic
heart conditions.
DOSAGE & FREQUENCY
• For Angina: The usual Post-Administration:
starting dose is 10 mg
twice daily, which may 1. Monitoring and Evaluation:
be increased to 20 mg
twice daily depending Monitor blood pressure regularly,
on the patient’s especially after initiating therapy or
response and tolerance. increasing the dose. Nicorandil can
The dose can be cause significant hypotension,
adjusted to minimize particularly in older adults or those
side effects, especially with other antihypertensives.
in patients prone to
headaches. Assess for anginal relief: Monitor how
well the patient’s anginal symptoms
are controlled and whether there is a
reduction in frequency and severity of
chest pain episodes.
Watch for adverse effects: Common
complaints such as headache or
gastrointestinal issues (e.g., ulcers)
should be closely monitored and
managed.
2. Patient Education (Post-
Administration):
Reinforce the importance of
adherence to medication, even if side
effects such as headaches occur, since
they often diminish over time.
