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Doc-20250614-Wa0064 250615 084914

The document outlines key topics in pharmacology, focusing on various systems and drug classes, including cardiovascular, renal, anti-neoplastic, autacoids, anti-thyroid drugs, corticosteroids, and antimicrobials. It includes specific questions and areas of discussion for each topic, such as the mechanisms of action, clinical implications, and adverse effects of various drugs. The aim is to provide a comprehensive understanding of these pharmacological agents and their applications.

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barmananubhab00
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10 views2 pages

Doc-20250614-Wa0064 250615 084914

The document outlines key topics in pharmacology, focusing on various systems and drug classes, including cardiovascular, renal, anti-neoplastic, autacoids, anti-thyroid drugs, corticosteroids, and antimicrobials. It includes specific questions and areas of discussion for each topic, such as the mechanisms of action, clinical implications, and adverse effects of various drugs. The aim is to provide a comprehensive understanding of these pharmacological agents and their applications.

Uploaded by

barmananubhab00
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as PDF, TXT or read online on Scribd
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PHARMACOLOGY IMPs

Here’s a few IMP Topics we’re going to be breaking down this week

●​ Cardiovascular System- Beta Blockers


●​ Renal System
●​ Anti-Neoplastic drugs
●​ Autacoids
●​ Anti-thyroid drugs and Corticosteroids
●​ Antimicrobials

PYQs

Cardiovascular System- Beta Blockers

●​ Explain the mechanism of antihypertensive action of beta blockers. Add a note on their
limitations.
●​ Why are beta blockers avoided in bronchial asthma?
●​ What is intrinsic sympathomimetic activity (ISA)? Give examples.
●​ Compare cardioselective and non-selective beta blockers. Discuss their clinical
implications.
●​ Why is abrupt withdrawal of beta blockers dangerous?​

Renal System

●​ Classify diuretics. Discuss the mechanism of action, uses, and adverse effects of loop
diuretics.
●​ Write short notes on: (any 2)
○​ Carbonic anhydrase inhibitors
○​ Mannitol
○​ Diuretics in hypertension
○​ Drug-induced nephrotoxicity
●​ Discuss the pharmacology of drugs used in the treatment of acute pulmonary edema.
●​ Describe the mechanism of action and clinical uses of potassium-sparing diuretics.

Anti-Neoplastic Drugs

●​ Name two cell cycle-specific anticancer drugs.


●​ Mention two toxicities of cisplatin and their prevention.
●​ What is tumor lysis syndrome?
●​ Name two hormonal agents used in cancer.
●​ Write a note on cancer chemotherapy-induced toxicities and their management.

Autacoids​

●​ Discuss the role of leukotrienes in asthma. Describe leukotriene pathway inhibitors and
their therapeutic uses
●​ Write short notes on the following:
○​ Platelet Activating Factor (PAF)
○​ Bradykinin
○​ Uses of prostaglandin analogues
○​ Eicosanoids in inflammation

Anti-thyroid drugs and Corticosteroids

●​ Discuss the pharmacological management of hyperthyroidism. Include drugs, their


mechanisms, and indications.
●​ Write short notes on:
○​ Differences between PTU and Methimazole
○​ Iodide in thyroid disease
○​ β-blockers in hyperthyroidism
○​ Drug-induced hypothyroidism
●​ Classify antithyroid drugs. Describe the mechanism of action, uses, and adverse effects
of thioamides.

Antimicrobials

●​ Classify β-lactam antibiotics. Describe the mechanism of action, spectrum, resistance


mechanisms, and adverse effects of penicillins.
●​ Classify antitubercular drugs. Write the mechanism of action, resistance, and adverse
effects of isoniazid.
●​ Write short notes on:
○​ Mechanism of action of sulfonamides
○​ Metronidazole
○​ Fixed Drug Combination for TB (FDCs)
○​ Mechanism of resistance to antibiotics​

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