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Compositional Analysis and Clinical Applications of Chandraprabha Vati – A

Classical Review

Article in World Journal of Pharmaceutical Research · May 2025

DOI: 10.20959/wjpr202510-36653

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 World Journal of Pharmaceutical Research
Sharma et al. World Journal of Pharmaceutical Research
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Volume 14, Issue 10, 286-293. Review Article ISSN 2277–7105

COMPOSITIONAL ANALYSIS AND CLINICAL APPLICATIONS OF

CHANDRAPRABHA VATI – A CLASSICAL REVIEW

Sonali D. Konkeri1, Pankaj Sharma2* and Aashish Patel1

1
Department of Kayachikitsa, KAHERs Shri BM Kankanawadi Ayurveda Mahavidyalaya,
PG Studies & Research Centre, Belagavi Karnataka.
2
Department of Rasayana Evam Vajikarana Tantra, KAHERs Shri BM Kankanawadi
Ayurveda Mahavidyalaya, PG Studies & Research Centre, Belagavi Karnataka.

ABSTRACT
Article Received on
25 March 2025, Ayurveda contains various kalpa and herbo-mineral formulations,
Revised on 15 April 2025, which are beneficial in many diseases in the broader aspects.
Accepted on 05 May 2025
DOI: 10.20959/wjpr202510-36653 Chandraprabha Vati is a common herbo-mineral preparation which is
efficient in various disorders mainly of genito-urinary and even in the
broader aspect, as it is said to be sarvaroganashini. Chandraprabha
Vati comes under khalaveeya Rasayana. The preparation described by
Sharangadhar Samhita is accepted by AFI and is taken here for the
critical review of its actions and properties. It is made up of 37
*Corresponding Author
ingredients and is indicated in prameha, mutravahasrotasa vyadhi,
Dr. Pankaj Sharma
anaha, shoola, shwasa, kasa, shukradosha, pandu, kamala,
Department of Rasayana
Evam Vajikarana Tantra, gudagatavyadhi, netraroga, dantaroga, kushtha, aartavaruja,
KAHERs Shri BM agnimandya and various other diseases. Overall, it has anti-
Kankanawadi Ayurveda inflammatory, renal protective, hepato-protective, anti-diabetic effects.
Mahavidyalaya, PG Studies
Under broader aspect it also has rasayana, vrushya, balya, tridosha
& Research Centre,
shamaka effect. Chandraprabha Vati is a miscellaneous formulation
Belagavi Karnataka.
and can be used in variety of ailments successfully. Hence this study is
done to understand and explore the formulation in various ways through the aspect of the
classics.

KEYWORDS: Ayurveda, Chandraprabha Vati, Rasayana, Mutrakrichra, Prameha.

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Sharma et al. World Journal of Pharmaceutical Research

INTRODUCTION
The main principle of Ayurveda is maintaining health of a person who is healthy, and treating
the diseased patient. In treatment protocol the main aim is to do shodhana and shamana of
vitiated doshas to achieve dosha samyata and other is to prevent the marmas (prana sthana)
from getting vitiated. There are 107 marmas discussed in the literature, and from those
marmas hridaya, basti and shiro marma are the vital marma, which on vitiation (aaghata)
may cause serious complication or death.

One such formulation which mainly act on one of the trimarma i.e., basti is Chandraprabha
Vati which comes under khalveeya rasayana and is a combination of herbal and mineral
drugs. Meaning of chandraprabha is, ‘Chandra’ means moon and ‘Prabha’ means lustre so
from this we can understand that the one which gives lustre like moon is chandraprabha.[1]
The term Chandraprabha is also said to be generated due to the fact that it represents the first
ingredient of the formulation. There is difference in opinion of experts about the drug
Chandraprabha.

It is described in different classical texts like Sharangadhar Samhita, Rasendra Sara

Sangraha, Bhaishajya Ratnavali, Siddha Yoga Sangraha, Bharata Bhaishajya Ratnakara,
Yoga Ratnakara etc. and have also narrated some difference in ingredients and indications. It
is recommended in prameha, mutravahasrotaja vyadhi, anaha, shoola, shwasa, kasa,
shukradosha, pandu, kamala, gudagatavyadhi, netraroga, dantaroga, kushtha, aartavaruja,
agnimandya and various other diseases. Hence has been attributed as “Sarvaroga Nashini.”[2]

OBJECTIVE
This writeup aims at exploring the various aspects where the Chandraprabha Vati is
indicated and could be utilised and how it acts in various diseases along with having main
action in mutrakrichra.

MATERIALS AND METHOD

Various Ayurvedic texts have been studied to gather all relevant information about this
formulation. Mainly we have found details about this from Sharangadhar Samhita
Madhyama Khanda 7/40-498[2] and Bhaishajya Ratnavali Prameha Chikitsa 102-1109.[3]
Also we have reviewed from scientific journals, internet publications for this present work.
Composition of chandraprabha vati: Chandraprabha Vati contains 37 individual drugs
which have Shilajatu and Guggulu present in maximum quantity i.e., 32 parts each and Sita

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 Sharma et al. World Journal of Pharmaceutical Research

and Loha Bhasma in 16 and 8 parts accordingly. Trivrita, Danti, Patraka, Tvak, Ela and
Vamshalochana are present in 4 parts each. Rest of the drugs in 1 part each. Chandra is the
very first and main ingredient used in this formulation which is described as Karpoora
according to AFI, hence gives the medicine its name.[4]

Table 1: Rasapanchaka and Doshaghnata of chandraprabha vati.

S.
Drug Latin Name Rasa Virya Vipaka Guna Quantity Action
No.
Tikta,
Cinnamomum Laghu, Tridosha-
1 Chandraprabha Katu, Sheeta Katu 1 part
camphora Tikshna hara
Madhura
Acorus Katu, Laghu, Vata-
2 Vacha Ushna Katu 1 part
calamus Tikta Tikshna kaphahara
Tikta,
Cyperus Laghu, Kapha-
3 Musta Katu, Sheeta Katu 1 part
rotundus Ruksha pittahara
Kashaya
Andrographis Laghu, Kapha-
4 Bhunimba Tikta Ushna Katu 1 part
paniculata Ruksha pittahara
Tinospora Laghu, Tridosha-
5 Amrita Tikta Ushna Madhura 1 part
cordifolia Snigdha hara
Cedrus Laghu, Kapha-
6 Devadaru Tikta Ushna Katu 1 part
deodara Snigdha vatahara
Curcuma Tikta, Laghu, Tridosha-
7 Haridra Ushna Katu 1 part
longa Katu Ruksha hara
Aconitum Tikta Laghu, Tridosha-
8 Ativasha Ushna Katu 1 part
heterophyllum ,Katu Ruksha hara
Bberberis Tikta, Laghu, Kapha-
9 Darvi Ushna Katu 1 part
aristata Kashaya Ruksha pittahara
Laghu, Kapha-
10 Pippali moola Piper longum Katu Ushna Katu 1 part
Ruksha vatahara
Laghu,
Plumbago Kapha-
11 Chitrak Katu Ushna Katu Ruksha 1 part
zeylanica vatahara
Tikshna
Katu,
Coriandrum Tikta, Laghu, Tridosha-
12 Dhanyaka Ushna Madhur 1 part
sativum Madhur, Snigdha hara
Kashaya
Lavana
Terminalia Laghu, Tridosha-
13 Haritaki Varjit Ushna Madhua 1 part
chebula Ruksha hara
Sarv Ras
Lavana
Emblica Tridosha-
14 Amalaki Varjit Sheeta Madhura Guru 1 part
officinalis hara
Sarv Ras
Terminalia Laghu, Kapha-
15 Vibhitaki Kashaya Ushna Madhura 1 part
bellirica Ruksha pittahara
Piper Laghu, Kapha-
16 Chavya Katu Ushna Katu 1 part
retrofractum Ruksha vatahara

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Laghu,
Katu, Kapha-
17 Vidanga Emblica ribes Ushna Katu Ruksha 1 part
Kashaya vatahara
Tikshna
Laghu,
Scindapsus Kapha
18 Gajapippali Katu Ushna Katu Ruksha 1 part
officinalis shamaka
Tikshna
Zingiber Kapha
19 Shunthi Katu Ushna Madhura Snigdha 1 part
officinalis vatahara
Laghu,
Katu, Kapha-
20 Maricha Piper nigrum Ushna Katu Ruksha 1 part
Tikta vatahara
Tikshna
Laghu, Kapha-
21 Pippali Piper longum Katu Anushna Madhura 1 part
Snigdha vatahara
Purified
Makshik Katu, Laghu, Kapha-
22 copper iron Ushna Katu 1 part
bhasma Tikta Tikshna pittahara
sulphate
Laghu,
Hordeum Katu, Kapha-
23 Yava kshara Ushna Katu Ruksha, 1 part
vulgare Kshara vatahara
Sara
Katu, Laghu, Kapha-
24 Sajji kshara Ushna Katu 1 part
Kshara Tikshna vatahara
Saindhava Lavana, Tridosha-
25 Sheeta Madhura Laghu 1 part
lavana Madhur hara
Lavana, Tikshna,
26 Vida lavana Ushna Madhura 1 part Vatahara
Madhura Sukshma
Sauvarchala Lavana, Laghu,
27 Ushna Madhura 1 part Vatahara
lavana Madhur Sukshma
Madhur, Laghu,
Operculum Kapha-
28 Trivrita Katu, Ushna Katu Ruksha 4 parts
terpenthum pittahara
Tikta Tikshna
Tikshna,
Katu, Kapha-
29 Danti Baliospermum Ushna Katu Sara, 4 parts
Kashaya vatahara
Laghu
Katu, Laghu,
Cinnamomum Kapha-
30 Patraka Tikta, Ushna Katu Ruksha 4 parts
tamala vatahara
Madhur Tikshna
Katu, Laghu,
Cinnamomum Kapha-
31 Twak Tikta, Ushna Katu Ruksha 4 parts
verim vatahara
Madhur Tikshna
Madhur, Laghu, Tridosha-
32 Ela Elettaria Sheeta Madhura 4 parts
Katu Ruksha hara
Laghu,
Bambusa Kashay Kapha-
33 Vamshalochana Sheeta Madhura Ruksha 4 parts
bambos Madhur pittahara
Tikshna
Madhur, Kapha-
34 Loha bhasma Iron Sheeta Madhura Guru 8 parts
Tikta pittahara
Saccharum Guru,
35 Sita Madhur Sheeta Madhura 16 parts Pittahara
officinalis Snigdha
36 Shilajatu Asphaltum Katu, Ushna Katu Guru, 32 parts Kaphahara

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 Sharma et al. World Journal of Pharmaceutical Research

Tikta Ruksha
Laghu,
Katu,
Commiphora Snigdha, Tridosha-
37 Guggulu Tikta Ushna Katu 32 parts
mukul Picchila, hara
Kashaya
Sara

DISCUSSION
Analysis of rasa panchaka of chandraprabha vati: To understand the function of the
medicine, one should know about their properties like rasa, guna, virya, vipaka and doshic
action. Maximum drugs from the Chandraprabha Vati are katu, tikta rasa, ushna veerya and
gunas like laghu, ushna, tikshna, ruksha. It is tridoshahara but more commonly act as
vatakapha shamaka. The ingredients also help in apana vayu anulomana, shodhana of
bahudrava shleshma and decreases the vitiated kleda. Here for the purpose of the study the
reference is taken from Sarangadhara Samhita Madhyam Khanda, where total 37 drugs are
combined to prepare this formulation or Yoga.

Prameha: Prameha is a condition in which there will be atipravritti of mutra due to

increased chala guna of vata dosha. The main factors in samprapti of prameha are kledak
kapha dushti, dhatwagni mandya, dhatu shaithilya. Hence here sthira and stambhana line of
treatment along with shodhana and deepana, pachana karma should be adopted.[5]
Chandraprabha Vati due to its laghu, ruksha guna helps in shodhana of vitiated shleshma
and kleda also katu-tikta rasa, ushna virya helps in this process. Deepana and pachana karma
reduce the dhatwagni mandya. Shilajatu and guggulu have main properties like rukshana and
chedana which will act on kapha dosha and also as rasayana. As described in samhitas,
kledavahan is karma of mutra and Chandraprabha Vati contains drugs like musta, devdaru,
tamalpatra, dhanyak, etc are mutrajanaka in nature which reduces the kled.[6]

Mutrakrichra: Mutrakrichra is caused due to srotorodha of mutramarga by vitiated

tridoshas and apan vayu dushti. Most of the drugs in Chandraprabha Vati have katu-tikta
rasa, ushna virya and laghu, ruksha guna which helps to remove the avarodha of srotas of
mutravaha srotas.[6] Also one of the main complaint of mutrakrichra is burning micturition.
Chandraprabha Vati has alkaline substances like Yavakshara and Svarjikakshara which will
help in reducing the pH of urine and further alleviating the complaint of burning micturition.
Guggulu is proven drug which have anti-inflammatory property, thus relieving inflammatory
conditions in entire genito-urinary tract.[7] Drugs like devadaru, ela, vidanga, panchalavana
have vatanulomaka properties which reduces apana vayu dushti. The drug Chandraprabha

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Sharma et al. World Journal of Pharmaceutical Research

Vati in this combination is rasayana, tridoshaghna, mutrala with deepana-pachana and

sheeta veerya properties which help in correcting the agni, there by overcoming the
pathogenesis of mutrakricchra.[8] Chandraprabha Vati is recommended in urinary tract
infection on the basis of its anti-inflammatory, antioxidant and alkalizing properties and also
maintain the flora of urinary tract.[9]

Mutraghata: In mutraghata, the production of mutra is less, Chandraprabha Vati contains

drugs like musta, devdaru, tamalpatra, dhanyaka, etc are mutrajanaka in nature, which
enhances the production of mutra.[6]

Ashmari: In this context the main steps of treatment could be ashmari bhedana,
mutravirechana, deepana pachana, vedanasthapana and shothahara. The constituents of
Chandraprabha Vati have ashmari bhedana, mutrala, vedanasthapana, shothahara, basti
shodhana, daha shamaka and deepana pachana properties. Which will further lead to
disintegration and expulsion of ashmari from urinary tract. The drugs like karpoora, musta,
devadaru, guggulu, triphala, ela, shilajati, makshika bhasma act as analgesic and help in
reducing pain.

Vibandha: It may be considered as apana vata vaigunya and can be understood as

constipation. Rukshata of pakwashaya is one of the important causes for vibandha and the
ingredients of Chandraprabha Vati helps in deepana, pachana and apana anulomana thereby
relieving vibandha.

Vicharchika kushtha: Vicharchika kushtha has kapha dominance in it and it is a

raktapradoshaja vyadhi which can be correlated with eczema. Chandraprabha Vati also has
the properties like kushthaghna, kandughna and krimighna.

Arsha & Bhagandara: Vata is the predominant dosha accompanied by Pitta and Kapha in
this condition. Hence Chandraprabha Vati helps in management of the same.

Aartavaruja: Aartavaruja or Kashtartava is explained in classics under the spectrum of

yonivyapada. It is the commonest gynaecological complaint. It occurs due to tridosha dushti
and mainly due to vata predominance in yoni. Especially there is derangement of apana and
vyana vata. The properties of Chandraprabha Vati are vata anulomaka and kaphahara which
maintain the proper functioning of apana vata. Also, it shows fruitful results in aartava ruja
and shukradhatugata roga.[6]

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Sharma et al. World Journal of Pharmaceutical Research

Yakrut vikara: In Yakruta vikaras (hepatomegaly), due to tikta katu rasa, kaphahara and
mutrala properties of Chandraprabha Vati it helps in reducing the symptoms. In kumbha
kamala, jaundice patients end up in ascites with portal hypertension. The liver tissues are
replaced by scar tissue. So, Chandraprabha Vati possesses properties like tikta madhura
rasa, agni dipana, yakrut vishesha and Rasayana.[6]

Apart from these, Chandraprabha Vati is utilised in shoola, granth arbuda, aantravruddhi,
shwasa, kasa, aagnimandya, aruchi and as vrushya and rasayana due to its composition with
shilajatu, guggulu, makshika and lauha like druga, with qualities of srotoshodhana and
kledashoshana. As per Gune Shashtri, the drugs like suvarnamakshika, lauha bhasma help in
in improving and increasing the rakta dhatu and is also pittashamaka and sthambhaka.
Shilajatu have the properties of rasayana shukra – artava doshanashaka and hence will
improve the dhatu pariposhana karma. Guggulu on the wide aspect acts as vata shamaka,
shothanashaka, balya and rasayana. And the other drugs have the properties of deepana,
pachana and mutrala.

CONLCUSION
Chandraprabha Vati, with its unique combination of katu-tikta rasa, ushna virya, and laghu-
ruksha guna, exhibits deepana, pachana, shodhana, and rasayana properties. It effectively
balances tridoshas, particularly vata and kapha, offering therapeutic benefits in prameha,
mutrakrichra, ashmari, and various systemic disorders by promoting agni and
srotoshodhana. Further research on Chandraprabha Vati is warranted to validate its
pharmacological actions, standardize its formulation, and explore its molecular mechanisms,
especially in conditions like Prameha and Mutrakrichra. Clinical trials and experimental
studies can strengthen its evidence-based application and enhance its integration into modern
therapeutic protocols.

Financial Support and Sponsorship

Nil.

CONFLICTS OF INTERESTS
There are no conflicts of interest.

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