(Q1) Gen Bio
(Q1) Gen Bio
3. Golgi Apparatus
- A series of f;attened sacs in convex 6. Chloroplast
shapes - Contains pigments called chlorophyll
- Processes and packages proteins and
substances produced by cells
- Found in plant and animal cells
4. Lysosome 7. Vacuoles
- Spherical vesicle containing digestive - Storage for water, food, enzymes,
enzymes that break down wastes wastes, pigments, etc.
- Autophagy “self eating”
- Phagocytosis (cells engulf other cells)
- Helps in programmed cell death
(Apoptosis)
8. Peroxisome
- Single-membrane microbody
- Contains enzymes that transfer H2
from various substrates to O2
producing H2O2
- H2O2: toxic peroxisome converts it to
H2O
9. Ribosomes
- Sites where the cell assembles
proteins
- Not bound by a cell membrane
- Two types: Free & Bound
10. Centrioles
- Aids in cell division by helping move
the genetic material
- Involved in organizing microtubules
(cytoskeleton) in the cytoplasm
Lesson 3 - Prokaryotic vs Eukaryotic Cells
3. Sperm Cell/Spermtozoon
- Function: Fertilize egg cells
- Characteristics: Long tail to
swim (flagella), numerous
mitochondria, chemical on the
head for egg cell entry
4. Egg Cell/Ovum
- Function: Carries genetic
material
- Characteristics: Large and
bulky, chemical change in the
membrane prevents
Lesson 4 - Cell Specialization
fertilization of more than one
- Cell differentiation sperm
- How generic cells change to different
types of cells for special functions 5. Nerve Cell/Neuron
- Function: Carry nerve impulses
through the body
In Animals - Characteristics: Long, thin
axon, branching dendrites,
myelinated
6. Muscle Cell nutrients throughout
- Function: Facilitate movement the plant
- Characteristics: Elongated and
elastic, numerous 3. Ground Meristem
mitochondria - will form the ground
tissues comprising
In Plants parenchyma,
1. Guard Cell collenchyma, and
- Function: Regulates rate of sclerenchyma cells
transpiration
- Characteristics: Cell wall has 2. Lateral Meristem
varying thickness - SECONDARY growth
- growing in: shoot, stem
2. Photosynthetic Cells 2 types: vascular cambium and
- Function: Produces food cork cambium
through photosynthesis 1. Vascular cambium
- Characteristics: Contains many - gives rise to secondary
chloroplasts xylem and phloem
Trichomes:
- in leaves and stems
- hair-like outgrowths that prevent
water loss and reflect excess light
LOWER EPIDERMIS
Guard cells:
- specialized structures that regulate
Organogenesis: the opening and closing of
2. development of the plant organs stomata
and occurs at the shoot system (such
as terminal buds) Stomata:
- slit-like structures which aids in the
3. Permanent Tissues exchange of gases between plants
- NON-dividing cells and the environment
- generally responsible for
photosynthesis LATERAL VIEW
1. Adaxial
2 types of Permanent Tissues - FRONT towards sunlight
1. Simple Permanent 2. Abaxial
- ONE kind of cell - BACK with veins
- 2 types: epidermal and ground
2. Ground
1. Epidermal
- photosynthesis (middle
- Epidermis: covers whole
layer)
body of nonwoody /
- 3 types: parenchyma,
young woody plants
collenchyma,
and is protected by a
sclerenchyma
waxy cuticle
- protects lower and
upper parts of leaves
- Cuticle: prevents loss of
water and invasion of
disease-causing
microorganisms
3. Sclerenchyma
2 KINDS OF SCLERENCHYMA
1. Sclereids
- strengthen seed coats and
are responsible for
gritty-textured flesh of
some fruits
2. Fibers
- used commercially as
components of rope and
flax fibers
2. Complex Permanent
- TWO or MORE kinds of cells
- 2 types of Vascular Tissues:
xylem and phloem
1. Xylem
- carries water and minerals
from the roots to the leaves
● Tracheids:
- thin and elongated cells where
water passes through
● Vessel Elements:
- have perforated plates that
allow the transport of water
through the vessels
Lesson 6 - Animal Tissues
Hierarchy of Biochemical Organization
SIMPLE COLUMNAR
PSEUDOSTRATIFIED COLUMNAR
Tissues
- groups of cells that are similar in
structure and function
STRATIFIED SQUAMOUS
4 Types of Animal Tissues
1) Epithelial Tissue
2) Connective Tissue
3) Muscular Tissue
4) Nervous Tissue
STRATIFIED CUBOIDAL
1. Epithelial Tissue
- forms the inner and outer lining of
organs, the covering in surfaces, and
the PRIMARY glandular tissue of the
body
- made up of tightly packed cells
because they cover and protect
STRATIFIED COLUMNAR
bodily structures
SIMPLE SQUAMOUS
2. Connective Tissue
- characterized by the presence of
ground substances and fibers that
support, bind, and protect organs
SIMPLE CUBOIDAL
Examples: hyaline cartilage, fibro
cartilage, elastic cartilage
Function: protection and support
REMEMBER!
CARTILAGE Tendons -> muscle to bone
- more flexible matrix than bone Ligaments -> bone to bone
- cartilage cells called chondrocytes
LOOSE CONNECTIVE TISSUE
- matrix contains more cells and lesser 3. Muscular Tissue
fibers than dense connective tissue - made up of highly specialized cells
so it is softer that contract to cause movement
Examples: adipose tissue or fat tissue
Function: protection, insulation,
storage, and support
SKELETAL MUSCLE
- attached to the skeleton or bones
Description:
- long, cylindrical, striated (with visible
stripes), and multinucleated (with
more than one nucleus)
Muscle Control: voluntary
SMOOTH MUSCLE
- found in the walls of hollow organs
such as intestines, stomach, bladder,
blood vessels, and uterus
Description:
- made up of nonstriated,
uninucleated, and spindle-shaped
(have pointed ends) cells
BLOOD Muscle Control: involuntary
- plasma
- cellular components consist of blood CARDIAC MUSCLE
cells - found in the heart
- with fibers that are only visible during Description:
clotting because they are made up of - uninucleated (one nucleus) and has
soluble proteins striations
Examples: blood and blood cells - has intercalated disks
Function: transport of substance, Muscle Control: involuntary
immune response, and blood clotting
4. Nervous Tissue
- mainly contain networks of nerve
cells that possess irritability and
conductivity to allow the
transmission and reception of
electrochemical impulses
MICROGLIAL CELLS
- ovoid cells in the CNS that can
transform into a phagocytic
macrophage to clean neuronal
debris and wastes
EPENDYMAL CELLS
- ciliated cells that line the central
cavities of the brain and the spinal
cord and form a fairly permeable
membrane between the cavities with
cerebrospinal fluid and the tissues of
CNS
Chromatid
- Half of a newly duplicated
SCHWANN CELLS chromosome
- surround all the nerve fibers and - Can refer to an unreplicated
produce myelin sheath similar to the chromosome
oligodendrocytes
Chromosome
- Packaged and organized structures
containing DNA of a living organisms
- If DNA is ready for cell division, it is
called chromosome
Gap 1 - S Phase
- Is there any damage in the cell’s
DNA?
- Is the cell large enough? Does it have
the necessary energy reserves and
doubled organelles?
- If not -> Gap 0 (resting phase)
0 gap phase
- Is the environment suitable?
Metaphase - Anaphase
- Are spindle fibers properly attached?
Aside from checkpoints, there are
regulatory proteins. These change
concentration when needed.
Cyclin
- Rise and fall at specific times
Kinase
- Speeds up phosphorylation (catalyst)
Phosphorylation = turning ON
Dephosphorylation = turning OFF
Metaphase
- Sister chromatid aligning at
Cyclin-dependent kinase (Cdk)
metaphase plate
- Becomes activated during
- Nucleolus and nuclear
phosphorylation
envelope disappear
completely
- Each chromosome receives
spindle fibers from the pair of
centrioles which are attached
to the kinetochores*.
MITOSIS
Prophase
- Chromatin condenses into
chromosome
- Nucleolus disintegrates ** Centromere - Binds 2 sister chromatids
- Mitotic spindle starts to form *** Telomere - Shrinks over time because of
- When nuclear membrane aging, the telomere on jelly fish last more as
disappears, they spread along the they live longer. It also serves as protection
cytoplasm for genetic material.
Anaphase
- The mitotic spindle pulls and
separates the sister
chromatids apart.
- The chromatids, now called Telophase - Cytokinesis (splitting of
daughter chromatids, are then cytoplasm)
pulled toward the opposite - Centrioles and all organelles
poles. are distributed in each
- The double-stranded daughter cell.
chromosomes separate - Complete separation of the
(centromere breakage) and cytoplasm produces two
move to the direction of the identical DIPLOID* daughter
centrioles. cells.
- A cleavage furrow* is produced * Has 2 sets of chromosomes.
to the opposite pull of the
centrioles.
Called cleavage furrow in animal cells and
cell plate in plant cells. Both result in the
appearance by which the cell is about to be
torn apart.
Metaphase I
- Nuclear envelope and
nucleolus disappear Telophase - Karyokinesis I
completely. - Spindle fibers disappear.
- Centrioles produce spindle - Nuclear envelope and nucleoli
fibers that will attach to the reappear.
kinetochore of the
homologous chromosomes.
- Homologous chromosomes
align to the metaphase plate.
- Notice that the loci or arms
of each sister chromatid vary
in color, this is because they
obtained a different but
same set of genes during
crossing-over.
Telophase - Cytokinesis I
- Complete separation of
cytoplasm and organelles with
two haploid daughter cells.
Anaphase I
- Reduces diploid homologous
number to haploid. Centrioles
pull each diploid homologous
pair to opposite poles of the
cell. Haploid sister chromatids
are formed.
MEIOSIS II
Telophase - Karyokinesis II
- Spindle fibers disappear,
releasing chromatids while the
nuclear envelope and
Metaphase II nucleolus reappears.
- Nuclear envelopes and - Results in UNDUPLICATED
nucleoli disappear completely. chromosomes.
- Each haploid chromosome
receives spindle fibers from
the pair of centrioles which are
attached to the kinetochores.
Haploid chromosomes align to
the central metaphase plate.
Telophase - Cytokinesis II
- Complete separation of each
cytoplasm and organelles,
forming four haploid daughter
cells.
ANEUPLOIDY
- state in which a cell has an abnormal
number of chromosomes
- in diploid organism, the most
common forms of aneuploidy are
monosomy and trisomy
* The four daughter cells containing haploid
chromosomes are ready to become 4 sperm CHROMOSOMAL CONDITIONS
cells in the testes of males or 3 polar bodies 1. Down Syndrome or Trisomy 21
and 1 egg cell in the ovary of females. - extra chromosome 21
- some physical characteristics of the
down syndrome include the
following:
- protruding tongue,
Lesson 9 - Chromosomal Conditions - small stature, and a
- short neck,
- eyes that slant upward
NON-DISJUNCTION
Phytosterol vs Cholesterol
5. Transport proteins
- Channel protein: have channels
where water molecules or other
solutes pass
- Carrier protein: alternates between
two shapes, moves a solute across
the membrane during the shape
change
- Membrane proteins:
- Transport
- Adhesion
- Recognition
- Receptor
1) ISOTONIC
- concentration of dissolved
substances in the solution is the
SAME as the concentration of
dissolved substances inside the cell
2) HYPOTONIC
- water enters a cell by osmosis,
causing the cell to SWELL and
BURST (CYTOLYSIS)
3) HYPERTONIC Active Transport
- water leaves a cell by osmosis, - Energy (ATP) is required
causing the cell to SHRINK - Against the concentration gradient
(PLAMOLYSIS)
Transporters/Carriers
● Uniporters - move one molecule at a
time
● Symporters - two molecules at a
time in the same direction
● Antiporters - two molecules at a
time in opposite directions
Bulk Transport
Endocytosis - taking in material by
enclosing it in a vesicle
● Phagocytosis
● Pinocytosis
● Receptor-mediated endocytosis
- small molecule can be linked from
end to end in countless ways to form
the polymers
Lesson 12 - Enzymes
PROTEINS
- made up of amino acid monomers
joined by a peptide bond
MONOMERS AND PROTEINS
TYPES OF METABOLISM
1. Catabolism Anabolism
a) Catabolism (exergonic)
- breakdown of materials
b) Anabolism (endergonic)
- builds complex materials from
simpler ones
TERMS
ENZYMES
- substances (proteins) that catalyze
chemical reactions
- three-dimensional protein
3 PARTS OF AN AMINO ACID configuration, with an active site
from where the substrate binds
CATALYST
- speeds up chemical reactions by
decreasing the activation energy
SUBSTRATE
- often an organic molecule, a
substrate possesses a structural
feature that complements the
geometry of the enzyme’s active site
Keratin
- protein that is the main component
in hair and nails
METABOLISM
- sum of all the chemical activities
taking place in a organism
DIFFERENT ENZYME MODELS
1. Lock-and-key model
ENZYMES PROCESS
3. Enzyme-Substrate Complex
TYPES OF ENZYMES
TABLE OF GLANDS AND ENZYME NAME