Hepatitis A, B, C and HIV: The Hepatitis Education Project Seattle, Washington
Hepatitis A, B, C and HIV: The Hepatitis Education Project Seattle, Washington
Topics of Discussion
Goals
Increase awareness and understanding Prevent transmission Educate patients about care and treatment
Ground Rules
Open and interactive Educational focus Respectful and attentive No medical diagnosis
Liver Function
Hepa means liver; itis means inflammation 2nd largest organ Performs over 500 different functions Lacks nerve endings Able to regenerate
Hepatitis Viruses
Hep A
Fecal-oral transmission Contaminated food & water Blood & bodily fluids
Blood
Hep B
Hep C:
Transmitted via contaminated blood & bodily fluids Risk of sexual transmission is high
Hepatitis B
Vaccine preventable In the U.S. most adults get over this infection on their own (90-95%) People infected for a long time have a higher risk of getting liver cancer
Liver cancer possible before cirrhosis (unlike HCV) Liver cancer screening is important
Protect Yourself
Use condoms
Hepatitis C
Hepatitis C is a virus transmitted via contaminated blood There is NO VACCINE It is very common U.S. and Worldwide
About 4-5 million Hep C+ people in the U.S. About 200 million Hep C+ people in the World
Injection drug use Tattoos (especially in jail or prison, street tattoos) Blood transfusions (pre-1992) Intranasal drug use
Occupational exposure
Fighting
Drug Use is #1
works needles, syringes, cottons, cookers, pipes, straws, rinse water, etc.
Cleaning with bleach is preferred, but isnt reliable against hepatitis viruses
Tattoos
Tattoos done in prison or jail are the most risky Best protection: get tattoos at licensed shops (autoclave, disposable inks and needles)
Get tested
First blood test looks for exposure. This is called an Antibody test. Second blood test looks for virus. This is called a PCR or confirmatory test.
25% Resolve
75% Chronic
Resolve (25)
Chronic (75)
Stable (34)
Cirrhosis (41)
Mortality (25)
Healthy livers are plump and smooth Cirrhotic livers are nodular; bumpy and shrunken
Dangerous Combinations
These can cause much worse & much faster liver damage
Symptoms of Hep C
Most people have no symptoms.
Symptoms can include: Fatigue (frequently tired) Memory or concentration problems (brain fog) Joint pains Insomnia (cant sleep) Depression
Liver Biopsy
Gives you a scar stage, a rating of the amount of scarring Stages of scarring:
No scarring Mild Moderate scarring, Treatment maybe Bridging fibrosis, Treatment yes! Cirrhosis, Treatment yes! (if liver can tolerate)
Types of Hep C
Hepatitis C is like a family with 6 different brothers or sisters. These siblings represent the different genotypes of Hep C
Genotype 1: needs one year of treatment, by far the most common type in the U.S. Genotype 2 or 3: needs six months of treatment
Is there a cure?
Yes, for many but not all.
Hep C Treatment
Treatment Goals
Kill the virus Stop scarring of the liver Prevent cirrhosis Get rid of the fatigue and other symptoms
Interferon
Interferon is an injection given just under the skin 3 times per week Pegylated interferon is injected once a week.
Side Effects:
Ribavirin
Side Effects:
Anemia low blood, makes a person feel tired
Rash Insomnia
Loss of appetite
Cough
Protease Inhibitors
Two new drugs: Telaprevir Boceprevir Both are oral medications taken every 8 hrs Both were added to IFN/riba treatment in 2011
Side Effects:
Telaprevir main side effect: Rash Boceprevir main side effect: Anemia
Alternatives to Treatment
May be useful for easing side effects
Milk thistle
Heliotropium Skullcap Jin Bu Huan Germander Sassafras Comfrey Senna Valerian Pennyroyal
Share needles or works Share tattoo equipment Share razors, nail clippers or toothbrushes Donate blood
Get tested
Limit alcohol Get vaccinated against Hep A and B Talk with your doctor to find out if you need treatment
Books on Hep C are available in all Washington State prison libraries Go online to learn more at http://www.hcvadvocate.org Visit your local Public Health Clinic Contact the Hepatitis Education Project Phone: 1-800-218-6932 Address: 911 Western Ave. #302, Seattle, WA 98104 Websites: http://www.hepeducation.org http://hcvinprison.org