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Lec 2 - Haematopoiesis

The document discusses haemopoiesis, the process of blood cell formation, and the sites where it occurs throughout fetal development and adulthood. In fetuses, haemopoiesis begins in the wall of the yolk sac and later occurs in the liver and spleen. By the fifth to ninth month of fetal development, the primary site shifts to the bone marrow, where it remains for the rest of one's life. The bone marrow contains haemopoietic stem cells that can differentiate into various blood cell types and is made up of trabecular and vascular components that support this process.

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18 views10 pages

Lec 2 - Haematopoiesis

The document discusses haemopoiesis, the process of blood cell formation, and the sites where it occurs throughout fetal development and adulthood. In fetuses, haemopoiesis begins in the wall of the yolk sac and later occurs in the liver and spleen. By the fifth to ninth month of fetal development, the primary site shifts to the bone marrow, where it remains for the rest of one's life. The bone marrow contains haemopoietic stem cells that can differentiate into various blood cell types and is made up of trabecular and vascular components that support this process.

Uploaded by

bujalkan
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as PPT, PDF, TXT or read online on Scribd
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HAEMOPOIESIS,

HAEMOPOIETIC SITE AND


BONE MARROW

BY,
MUHAMMAD NABIL FIKRI BIN ROSLAN
Learning Outcomes

In the end of this lesson, students should be able to:

1. Describe the process of haemopoiesis.


2. Identify the haemopoiesis site in fetus, infants, and
adults.
3. Describe the structure and functions of Bone
Marrow.
Site of haemopoiesis

Haemopoiesis
: The process
whereby blood
cells are
made.
Site of haemopoiesis

Begins in the wall of the yolk sac


2nd month the liver, followed by spleen
5th to 9th month onwards the bone marrow
Haemopoietic stem cell and progenitor cells

All blood cells derived from a common stem cell.

Immunophenotyping:

CD34+
CD38-

Stem cell (100x objective)


Bone marrow specimen
stained with Wrights
Stain
Diagrammatic representation of the bone marrow
pluripotent stem cell and the cell lines that arise from it
Bone marrow structure
Thank You

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