Benign Pelvic and Perineal
masses
Prof (M) Dr Mohd Hashim Omar
Jabatan Obstetrik & Ginekologi
Fakulti Perubatan, UKM
Introduction
Recognition of a pelvic or perineal mass
requires a complete familiarity with con
stitutes normal female pelvic anatomy
Definition of “Normal” differs depending on
pubertal status, phase of menstrual cycle,
occurrence of menopause, previous surgery
and known intercurrent disease.
Gynaecologic and Obstetrical
Pelvic Masses
Uterine Ovarian
Pregnancy Benign tumours (solid and
Leiomyomata cystic)
Adenomyosis Malignant tumours (mainly
Congenital anomalies
solid)
Carcinoma
Sarcoma
Pregnancy
Pyometra Ligamentary
Tubal Endometroid
Inflammatory(Hydro-S) Benign tumours
Pregnancy(ectopic) (Leiomyoma, haematoma)
Benign tumours (adenomatoid, Malignancy (mainly
myoma)
metastatic)
Carcinoma
Pelvic Anatomical Consideration
Ovaries Uterus
Prepubertal & Multiparous uterus
Menopause remain symetrically
Measure less than 2 cm larger 2-3cm larger
in its longest Diameter than nulliparous
AND not not clinically
palpable
Smaller (atrophic) in
prepubertal &
Fallopian Tube menopausal
Delicate and not
palpable
Pelvic Mass
Size
Preferably the mass is describe as anterior or
posterior, midline, left or right to a given
reference point ( usually Uterus)
Most often, uterine size is compared and
describe as the size of pregnant uterus at a
given gestation period
Measurement in cm is preferred
Pelvic Mass
Mobility or Fixation
The ovaries, fallopian tube, and uterus are
suspended by pliable, distensible ligaments
Highly mobile
usually the uterus move with the mass if the
mass arising from the uterus.
Inflammatory lesions, malignancy,
endometriosis, previous radiotherapy and
previous surgery diminishes mobility
Pelvic Mass
Consistency
To differentiate the mass is solid, cystic or
both component.
Benign, simple ovarian cyst are smooth and
soft (cystic)
Ovarian malignancy, fibroid are solid
Pelvic Mass
Tenderness
Tender uterus is typically adenomyosis or
endometritis
Salpingitis or tubal pregnancy will result in
tenderness to palpation or cervical motion
Torsion and infarction of mass can also lead
to tenderness
Pelvic Mass
Shape and Symmetry
Uterus is a symmetric structure
Enlargement of any of its components can lead to
an irregular enlargement
Symmetrical enlargement suggest pregnancy or
adenomyosis
Diagnosis and management of
pelvic masses
Premenarchal Female
No Physiologic ovarian lesion or pregnancy-related
masses
Mainly related to congenital anomalies involving
Complete or partial duplication of Mullerian system
Benign or malignant ovarian cyst (germ cell)
Congenital cyst of mesonephric system
Pelvic kidney
A careful history and examination including EUA, IVP
and serum tumour markers (AFP and Beta HCG) as
well as karyotyping should always be done.
Cont.
The sexual abuse also should be role out
Pelvic inflammatory disease and pelvic abscess
Chronic haematomas secondary to forced sex
Diagnosis and management of
pelvic masses
Menstruating Female
Intrauterine and ectopic pregnancy are always a
diagnostic consideration
Careful menstrual history, sexual activity and
pregnancy symptoms
Pattern of menstrual cycle, amounts and any pain
should be asked
Association factors eg. Fever, pain, dyspareunia
and progression
Constitutional symptoms
Diagnosis and management of
pelvic masses
Postmenopausal Female
Pelvic mass is consider omnious
Consider malignant
Functional cyst do not enter into the
differential diagnosis
Fibroid and endometriosis get smaller or
better during menopause
Silent PID lead to pelvic abscess should be
considered
Benign Uterine lesions
Leiomyomas of Uterus
The most common tumour of uterus
20-40% in women over 35 years old
Frequently cause no symptoms
It is the commonest indication for
hysterectomy
Growth of fibroid is faster and incidence of
fibroid in black women
Cont (fibroid)
Pathology
Is discrete and may be single or more
Cut surface has a glistening, white colour with a
characteristic whole-like trabeculation
Pseudocapsul comprised of compressed cell on the
outer layer
Occur in several location, cervix, uterus, broad
ligaments.
Symptoms may related to the size and site of the
fibroid
Cont (fibroid)
Pathogenesis
Aetiology is not established
Hormonal influence on the growth of
leiomyomas is obvious
Growth rapidly during pregnancy , OCP,
PCOS, granulosa cell tumour
Rarely before menarrche and regress after
menopause
Cont (fibroid)
Secondary Changes of Fibroid
Because of sparce in blood supply, fibroid are
subjected to severe degenerative changes
Hyaline degeneration is the most common and not clinically
significant and lead to Calcification
Cystic degeneration is an extreme form of hyaline
degeneration
Red degeneration occur in pregnancy and menopause
The main symptom is pain due to congestion and swelling
Sarcomatous degeneration is rare.
Cont (fibroid)
Sign and Symptoms
Compression symptoms eg. Discomfort, urinary
retention, constipation
Menstrual problems: Submucosa and intramural
fibroid.
Hydronephrosis and hydroureter
Polycytemia in Right broad ligament fibroid
Pain in red and sarcomatous degeneration
Cont (fibroid)
Treatment
Conservative
Asymptomatic
Pregnancy
Surgical
Symptomatic
Completed family : Hysterectomy
Not completed family: Conservative surgery/
Myomectomy
Benign Uterine lesions
Adenomyosis
Benign uterine disease caractersed by endometrial
glands and stroma found within the uterine
musculature
There is hypertrophy and hyperplasia of the
myometrium
Resulting a diffuse enlarged uterus
There is ectopic growth of endometrial tissue
The incidence is difficult to determine
50% asymptomatic
Adenomyosis (cont)
Pathology
Uterus is diffusely enlarged
There may be small, dark, bloody cystic area throughout
the of the uetrus within myometrium
Microscopically : islands of endometrial tissue includibg
glands and stromal scattered in the myometrium
50% of patient with adenomyosis have a uterine fibroid
When endometrial carcinoma is present, adenomyosis is
frequently associated
Implying a common aetiology factors such as hyperestrogenism
Adenomyosis (cont)
Clinical Characteristics and diagnosis
Patient is in between 40 to 50
Parous, and has symptoms of menorrhagia
Menorrhagia is resistant to hormonal treatment
Dysmenorrhoea in 25% of patient
Diagnosis is made clinically by the symptoms and
examination of symmetrically enlarged uterus
Diagnosis is only confirmed by HPE
Adenomyosis (cont)
Treatment
Medical treatment
Pseudopregnancy drugs: OCP/progesterone
Pseudomenopause drugs: Danazol/GnRH
Surgical treatment
Hysterectomy
Benign Ovarian Mass
Functional Cyst
Most commonly found during reproductive age
Rarely cause symptoms or require treatment
Follicular cyst
Normally only one follicle will goes to full development and
ovulation
Others degenerated and the follicular fluid is absorbed
Replaced by fibrous and hyaline
If fluid not absorbed: Follicular cyst.
Rarely beyond 7 cm diameter
Decrease in size and disappear within 6-8 weeks
Functional Cyst (cont)
Corpus luteum cysts
During pregnancy, CL may become cystic and
enlarged
No clinical significant; however if ruptured may
confused with ectopic
Rarely get twisted
Functional Cyst (cont)
Theca-lutein cysts
May occur in molar pregnancy
Large cyst derived from theca cells or luteinized
granulosa cells
Not require treatment unless it undergone torsion,
rupture or haemorrhage
Cause by excessive HCG stimulation
The cyst will disappear with the disease treatment
Benign Ovarian Mass
Luteoma of pregnancy
Uncommon
Occur in pregnancy and is the result of excessive response
of ovarian stroma to high level of HCG
Tumour disappear once pregnancy terminated
Occasionally they secrete androgen and cause hirsutism of
mother,and musculinization of female fetus
Tubo-ovarian inflammatory mass
Para-ovarian Cyst
Cysts arise from the mesonephric remnants and located in
the mesovarium
Benign Ovarian Mass
Benign neoplastic cysts
Epithelial tumour
Serous
Mucinous
Endometrial
Clear cell or mesonephroid
Adenofibromas
Brenner
Sex Cord Stromal Tumour
Thecoma, fibroma and Sertoli-Leydig cell
Germ Cell Tumours
Mature teratoma
Benign Perineal masses
Benign solid tumour Cystic tumor
Condylomata Epithelial inclusion
Seborrheic Keratosis cyst
Acrochordons Bartolin’duct (abscess
(fibroepithelial polyps) or cyst
Fibromas Mucous cyst
Neurofibromatosis Hydrocoele, hernia
Hidradenoma and/or cyst of the
Accesory breast canal of nuck
Sebaceous adenoma
Benign Perineal masses
Cystic Masses
Epidermal Inclusion Cyst
Sebaceous cyst
Extremely common on the vulva and usually
appear as multiple small, firm subcutaneous
nodule
Ocassionally are recurrently infected with
associated irritation, demanding incision and
drainage
Cystic Masses (cont)
Bartholin’s duct abscess/cyst
Bartholin’s gland entering the interoitus just above
the fourchette at the vaginal outlet
May be dilated as the result of chronic infection
and/or cyst formation
Thank