Basic principles of vascular
surgery
Anatomy
Physiology
Pathology
Pathophysiology
Clinical presentation.History, physical
exam.
investigation
management
physiology
Haemostasis vasoconstriction
platelet
aggregation
Coagulation intrinsic, extrinsic
Fibrinolysis
Renin angiotensin system
Vascular pathology
Atherosclerosis: placque
formation,flow
effect, fate of the
placque
Risk factors
Clinical sequelae : stenosis, occlusion,
thrombosis,
embolisation,
aneurysm
Vascular pathology
1-Trauma:RTA,falls, stabs, gun shot,
sharps Iatrogenic
DRUG ADDICT
2-Inflammatory: (VASCULITIS)
Takayassaue, Kawasaki, Beurger
Connective tissue (SLE, polyart. Nod.,
Rh. Art.,)
3-Spasmodic Reynauds dis.,
phenomenon
4-Conginetal malformation : venous,
arterial
AVM
symptomatology
Chief complaint, history of the
present illness
Peripheral vascular symptoms
atherosclerosis risk factors
Review of important systems
Peripheral vascular
symptoms
Acute ischaemia
Chronic ischaemia
Infection
Neuropathy
Foot trauma/injury
Syndromes amaurosis fugax,
dysphagia lusoria, Leriche , TIA, CVA
Atherosclerosis risk factors
Nonmodifiable age , gender , family
Modifiable D.M., Hypertension, Smoking
Dyslipidaemia, obesity,
stress
Review of systems
Cardiac
Cerebral
Renal
Gastrointestinal
Renovascular hypertension
10-20%of secondary hypertension
Uncontrolled despite 2-3 meds
Flash pul.oedema
Hypokalaemia
Captopril test
Doppler US., MRA
Angioplasty
Examination
Pulse, B.P., Edema
Local inspection
Colour elevation,
dependency
Skin trophic changes
Driness, hair, nails,
wasting
venous filling
Ulcers , Gangrene
Ulcers def., types
Gangrene
infarction
Necrosis
Examination
Palpation temp. pulses, cap. Filling
Auscultation carotid , femoral
Investigation
Bood work, ECG, CXR
Non invasive vascular lab
ankle/brachial index
exercise test , toe pressure
doppler ultrasound
Invasive angiography, CT, MRA
Medical Management
1-Risk factors control
2-improve blood flow
aspirin, pentoxyphylline
clopidogrel, anticoagul.
Aspirin mechanism of action
Phosphlipids---arachidonic acid----(cyclo-
oxygena)--endoperoxides:
In plt. --------thromboxane(throm.synth)
ATP-----ADP(plt
aggreg.+vasocons)
In blood vessel endoth.
Endoperox.----prostacyclin(stimulate adenyl
cyclase)
ATP------cAMP(plt
sgreg.+vasodil)
-----5AMP
Surgical management
For rest pain, ulcers, gangrene
Embolectomy , thrombectomy,
Vascular reconstruction
Endart.,repair,
resection+interposition,Bypass
Using saphenous vein (reverse/insitu)or
PTFE
Amputation toe, transmet.,
symes,BK,AK