ANGINA
By:p. DHILIP KUMAR
DEFINITION
Angina or chest pain is the clinical
manifestation of reversible myocardial
Ischemia
Causes of Angina
• Non cardiac conditions like anemia,
hypoxemia, anxiety, pneumonia, asthma,
physical exertion, COPD and low blood volume
• Cardiac conditions like coronary artery spasm,
coronary artery thrombosis, dysrrhythmias,
heart failure and valve disorders, aortic
stenosis, cardiomyopathy, tachycardia
Types of Angina
• Chronic stable Angina: It refers to chest pain that occurs intermittently
over a long period with the same pattern of onset, duration and intensity
of symptoms.
• Silent Ischemia: It refers to the ischemia that occurs in the absence of
any subjective symptoms.
• Nocturnal Angina or Angina decubitus: It occurs only at night but not
necessarily when the person is in the recumbent position or during
sleep.
• Prinzmetal’s Angina or Variant Angina: It occurs at rest usually in
response to spasm of a major coronary artery.
PATHOPHYSIOLOGY
Coronary atherosclerosis
Attraction of platelets to the arterial wall
Thrombus adhere to the wall of the artery
Occlusions of the coronary arteries
Lack of blood flow to myocardium
Anaerobic metabolism
Accumulation of lactic acid to the muscles
Angina pectoris
Assessment of Angina
P- precipitating events i.e. what events or activities
precipitated the pain
Q- quality of pain i.e. how is the pain felt whether
dull, aching, squeezing, tight or pressure type
R- Radiation of Pain i.e. to all what areas pain is
radiating
S- severity of pain i.e. on a scale of 0-10 rate the pain
T- timing of pain i.e. when the pain begins and the
duration and frequency of pain
DIAGNOSTIC EVAUATION
• History and physical examination
• ECG
• Chest X-ray
• Exercise stress test
• Echocardiogram
• Nuclear imaging tests
• CT scan
• Positron emission tomography
• Coronary angiography
• Laboratory test- CK-MB, CBC, Lipid profile, C- reactive protein,
myoglobin.
management
• Admn morphine sulfate to reduce pain.
• Drug therapy Anti platelet therapy (Aspirin)
• Admn Inj.Nitroglycerine
• β- Adrenergic blockers (Metoprolol, Inderol)
• Calcium channel blockers (Amlong, Nimodip)
• ACE inhibitors (captopril, ramipril)
• Fibronolytic agents (Streptokinase, Heparin)
• Percutaneous coronary intervention
SURGICAL MANAGEMENT
• Coronary artery bypass graft surgery(CABG)
• Minimally invasive direct coronary artery
bypass
• OFF- PUMP CORONARY ARTERY BYPASS
• Transmyocardial Laser
Revascularization(TMR)