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Immunopathology: Jamas Ari A Patologi Mulut Dan Maksilofasial FKG Unpad 2021

The document discusses immunopathology, which is the study of diseases caused by immune reactions and immune deficiencies. It covers topics like the immune system organs, hematopoiesis, the innate immune system, complement, the adaptive immune system, definitions of immunopathology, immunodeficiencies, autoimmunity, and hypersensitivity.

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058 Rayhan Alkumanonu Amrizal
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59 views18 pages

Immunopathology: Jamas Ari A Patologi Mulut Dan Maksilofasial FKG Unpad 2021

The document discusses immunopathology, which is the study of diseases caused by immune reactions and immune deficiencies. It covers topics like the immune system organs, hematopoiesis, the innate immune system, complement, the adaptive immune system, definitions of immunopathology, immunodeficiencies, autoimmunity, and hypersensitivity.

Uploaded by

058 Rayhan Alkumanonu Amrizal
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PPTX, PDF, TXT or read online on Scribd
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Immunopathology

Jamas Ari A
Patologi Mulut dan Maksilofasial
FKG UNPAD
2021
Immune system

Primary lymphoid organs—including the bone marrow and the


thymus—regulate the development of immune cells from immature
precursors. Secondary lymphoid organs—including the spleen,
lymph nodes, and specialized sites in the gut and other mucosal
tissues—coordinate the encounter of antigen with antigen-specific
lymphocytes and their development into effector and memory cells.
Blood vessels and lymphatic systems connect these organs, uniting
them into a functional whole.
Hematopoiesis

all functionally specialized, mature blood cells


(red blood cells, granulocytes, macrophages,
dendritic cells, and lymphocytes) arise from a
single cell type, the hematopoietic stem cell
(HSC). The process by which HSCs
differentiate into mature blood cells is called
hematopoiesis
Innate immune system

The main physical barriers—the body’s first line of defense


—are the epithelial layers of the skin and of the mucosal and
glandular tissue surfaces connected to the body’s openings;
these epithelial barriers prevent infection by blocking
pathogens from entering the body. Chemical barriers at
these surfaces include specialized soluble substances that
possess antimicrobial activity as well as acid pH. The
cellular innate immune responses to invasion by an
infectious agent that overcomes theinitial epitheli al barriers
are rapid, typically beginning within minutes of invasion.
These responses are triggered by cell surface or intracellular
receptors that recognize conserved molecular components of
pathogens.
Denditric cells
Complement

complement (spelled with an e)


refers to a set of serum proteins that
cooperates with both the innate and
the adaptive immune systems to
eliminate blood and tissue pathogens
The Major Pathways of
Complement Activation
Adaptive immune system
Definition of Immunopathology
 1. that branch of biomedical science concerned with IMMUNE RESPONSES to disease, with 
IMMUNODEFICIENCY diseases, and with diseases caused by immune mechanisms.
 2. the structural and functional manifestations associated with IMMUNE RESPONSES
 to disease or with diseases caused by immune mechanisms. adj., adj immunopatholog´ic.
(Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.)

The study of diseases or conditions resulting from immune reactions.
Farlex Partner Medical Dictionary © Farlex 2012

 The study of the role of immunological processes in the production of disease and in its diagnosis and treatment.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
Immunodeficiency

immunodeficiency disorders a
re 
a group of disorders in which 
part of the immune system is 
missing 
ordefective. Therefore, the
body's ability to fight infection
s is impaired. As a result, the p
erson with an immunodeficien
cy
disorder will have frequent inf
ections that are generally more
 severe and last
longer than usual
Autoimun
Hypersensitivity
Thank you

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