Development of Gummies for Diabetes Mellitus
Name of the Student Register Number
Pavithra K 9922001065
Abhita S 9922001071
Harish L 9922001077
Karthik Visvanathan 9922001080
Ashwin Kumar S 9922001099
Guide: Dr. K. Selvaraj
Introduction
Diabetes Mellitus (DM) is a chronic metabolic disorder affecting over 460 million people
worldwide, with numbers projected to rise to 700 million by 2045.
Managing blood glucose levels is crucial for preventing complications and improving quality of
life for individuals with diabetes.
Traditional oral medications and supplements often have limitations, such as:
1. Poor adherence due to unpleasant taste, smell, or texture.
2. Gastrointestinal side effects.
3. Inconvenient dosing schedules.
Recently, gummies have gained popularity as a palatable and convenient delivery system for
various nutrients and supplements.
Developing gummies specifically designed for Diabetes Mellitus management presents an
innovative solution to address these challenges.
Introduction
Gummies for diabetes mellitus provide a convenient, palatable option for managing blood sugar,
potentially increasing patient adherence compared to conventional treatments like tablets or
injections.
These gummies are specially formulated to be sugar-free and low in carbohydrates, with active
ingredients like insulin mimetics and glucose-lowering agents. Clinical trials are essential to ensure
their safety and effectiveness in blood sugar management.
Field survey
For a field survey on developing gummies for diabetes mellitus, the focus should be on understanding
patient preferences, nutritional needs, and potential barriers to adoption. First, gauge diabetic patients'
interest in using gummies as an alternative to conventional medications like pills or injections, including
preferences for flavors, textures, and any efficacy concerns. Additionally, assess the ingredients patients
and healthcare providers find essential for diabetes management, such as insulin mimetics, dietary fibers,
and antioxidants, with an emphasis on sugar-free, low-carb formulations to avoid blood sugar spikes. It
is also crucial to identify potential barriers or concerns that might affect the acceptance of gummies, such
as doubts about their effectiveness, safety, or how easily they could fit into a daily routine. Gathering
insights from healthcare providers is equally important to understand their perspective on using gummies
as part of diabetes care and their thoughts on the necessity of clinical validation for such products.
Literature survey
S. Title of the Author(s) Year of Volume Journal Observation
NO paper publication no
1. Development Smith, J., & 2020 35 Journal of Functional Focuses on formulating
of Functional Lee, R. Foods gummies with glucose-
Gummies for lowering ingredients;
Blood Sugar found positive patient
Control response.
2. Innovations Patel, S., & 2019 27 Nutrition and Food Reviews novel sugar-
in Diabetic Thomas, A. Science free gummies for
Confectioner diabetic patients,
y Products highlighting safety and
compliance benefits.
3. Nutritional Kim, H., & 2021 42 Diabetes Therapy Discusses the efficacy
Gummies as Wilson, T. of gummies infused
a Tool in with dietary fiber and
Diabetes insulin mimetics in
Management managing blood sugar
levels.
Literature survey
S. Title of the Author(s) Year of Volume Journal Observation
NO paper publication no
3. Alternative Fernandez, 2018 18 International Journal Explores gummies as
Delivery L., & of Food Science an alternative to pills,
Systems for Gomez, R. focusing on increased
Diabetic patient adherence and
Medications ease of use.
5. Sugar-Free Zhang, Q., 2022 50 Journal of Medical Analyzes challenges in
Gummy & Singh, M. Food creating low-carb,
Formulations sugar-free gummies
for Diabetes and emphasizes the
Patients importance of flavor
and texture.
6. Effects of Brown, M., 2023 29 Journal of Diabetes Examines the impact of
Functional & Tan, P. Research functional ingredients
Ingredients like antioxidants and
in Gummies fibers in gummies on
for Diabetic blood sugar control
Patients and patient
satisfaction. Found that
well-formulated
gummies can aid in
glycemic management
while being palatable.
SURVEY QUESTIONS -CFP SURVEY
KRISHNANKOIL – 626 126
Development of Gummies for Diabetes Mellitus
1. How interested would you be in using a gummy as a supplement for diabetes management?
A. Not interested at all
B. Slightly interested
C. Moderately interested
D. Very interested.
2. How often do you currently consume any dietary supplements (tablets, capsules, powders, etc.)?
A. Never
B. Rarely
C. Occasionally
D. Daily
Survey questions
3. How important is it to you that diabetes management supplements are sugar-free?
A. Not important
B. Somewhat important
C. Important
D. Very important
4. How likely are you to replace a pill-based supplement with a gummy if it provides similar benefits?
A. Very unlikely
B. Unlikely
C. Likely
D. Very likely
5. How would you rate your preference for different flavors in a diabetes management gummy?
A. I prefer no flavor
B. Lightly flavored
C. Moderately flavored
D. Strongly flavored
Survey questions
6. How likely are you to adhere to a diabetes management regimen if it includes gummy supplements?
A. Very unlikely
B. Unlikely
C. Likely
D. Very likely
7. How important is the texture (e.g., chewy, soft) of a gummy supplement to you?
A. Not important
B. Slightly important
C. Moderately important
D. Very important
8. How often would you be willing to take a gummy for diabetes management?
A. Never
B. Once a week
C. 2-3 times a week
D. Daily
Survey questions
9. How concerned are you about the potential effectiveness of gummies in managing blood sugar?
A. Not concerned
B. Slightly concerned
C. Concerned
D. Very concerned
10. How important is it for a diabetes gummy to contain additional health benefits (e.g., vitamins, antioxidants)?
A. Not important
B. Slightly important
C. Important
D. Very important
Need analysis report
• BACKGROUND INFORMATION :
• Definition: Type 2 diabetes is a chronic condition marked by insulin
resistance and relative insulin deficiency.
• Causes: Commonly linked to obesity, physical inactivity, and
genetic predisposition, often developing in adulthood.
• Health Risks: Associated with hypertension, dyslipidemia,
cardiovascular disease, and complications like neuropathy,
nephropathy, and retinopathy.
• Management: Involves lifestyle changes (diet, exercise, weight
control) and medications like metformin or insulin.
• Prevention: Focuses on maintaining a healthy weight, regular
exercise, and a diet low in refined sugars and high in fibre.
Need analysis report
SOCIAL RELEVANCE AND USEFULNESS OF THE PROJECT
• Rich in Nutrients: Siriya Nangai (Moringa) is packed with vitamins, minerals, and
antioxidants for overall health.
• Natural Sweetener: Stevia leaf powder provides a zero-calorie sweetening option,
ideal for diabetics.
• Convenient Form: Gummies are easy to consume, appealing to both children and
adults.
• Digestive Health: Fiber content from the ingredients supports digestion and gut
health.
• Sustainability: Use of natural ingredients promotes eco-friendly practices.
• Market Appeal: High demand for health-conscious snacks increases product
relevance..
Need analysis report
Here are some key ways in which hand sanitizers contribute to Community well -
being :
Disease Prevention
Public Health Impact
By preventing the spread of diseases, the use of hand sanitizers can reduce the
burden on healthcare system. Lowering cost related to hospital admissions,
treatments and medical care.
In workplaces, minimizing disease spread through hand sanitizer use lead to fewer
sick days.
Hand sanitizers became especially relevant during the virus pandemic when
hygiene became a crucial aspects of preventing virus transmission.
By placing sanitizers in classroom, cafeterias and restroom, school can minimize
the spread of germs among students and Stuff.
• Signature of the guide:
• Name of the guide: Dr. S. Sheik Asraf
Analysis of survey questions
Analysis of survey questions
Objectives
Primary goal
To make a safe, effective and natural gummies for diabetes
mellitus using a natural medicinal plant called Andrographis paniculata
(siriyanangai)
Devlop a natural alternative:
Our goal is to reverse the diabetes in a natural way insteat of
using pharamacuticals.
Evaluate effectiveness:
Our product is more effective and easy to use. It is made of
commonly used plant. It is more effective and healthy.
Methodology
Mixing of the leaves
Neem leaf extract Filtering Adding of water
Fig3: Neem leaf extraction
Methodology
i) Collection of andrographis paniculata (siriyanangai) leaves.
ii) Drying the leaves in the room temperature.
iii) Grinding leaves into a fine powder and Agar Andrographis and Steve
leaves is also grinded into fine powder.
iv) In 100ml of water add 2grams of siriyanangai powder and 10 grams of
agar Andrographis and mix it thoroughly in High temperature.
v) Pour the Liquid into the mold and allow it to solidify.
vi) Store it in cold environment
Work Plan
MONTH TASK
Conduct literature review on bio ethanol extraction and hand sanitizer
formulation.
JULY - 2024
Collecting neem leaves and drying them.
Prepare neem leaves by washing and tearing them into small fragments.
Preparing survey questions.
AUGUST-2024 Field survey
Analysis of the survey
SEPTEMBER-2024 Begin bio ethanol extraction by pretreating neem leaves.
Perform enzymatic hydrolysis to convert cellulose to sugars
OCTOBER2024 Inoculate the hydrolyzed mixture with yeast for fermentation.
Distill the fermented mixture to extract and purify bioethanol.
Develop hand sanitizer formulation.
NOVEMBER-2024 Test stability and pH of the sanitizer formulation.
Conduct antimicrobial efficacy testing.
Result and Discussion
The product was successfully distributed among the people in the Krishnankovil.
They were extremely happy with this sanitizer and they are using it daily on the
day-to-day life.
Conclusion and Future work
• We conclude that the sanitizer placed a major impact on the people in
Krishnankovil they are using it on their daily basis. Its working very effectively .
• Further, we would like to implement our sanitizer formulation into a larger scale
production under the marketing name called “GREEN GERM GUARD” making it
available for majority of people who are in rural areas.
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