Vector-Borne Diseases Workshop Presentations Epa Region
Vector-Borne Diseases Workshop Presentations Epa Region
EPA, REGION 9
VECTOR-BORNE
DISEASES
WORKSHOP
U.S. EPA OPENING
REMARKS
BIOLOGY AND
CONTROL OF VECTORS
AND PUBLIC HEALTH
PESTS
Vector-Borne Diseases
Biology and Control of Vectors
and Public Health Pests
CDR Joe Laco, MSEH, RS/REHS
Environmental Health Officer
CDC National Center for Environmental Health
Division of Emergency Environmental Health
Services Environmental Health Services Branch
60 Percent!
Brain Teaser – 2
75 Percent!
What animals are
responsible for more human
illness and death than any
other group of mammals?
61
Using the current CDC statistical
model, how many West Nile
infections occurred in Texas in
2012?
118,160
Based on a published study in the
October 2012 edition of Epidemiology
and Infection, how many projected West
Nile virus infections have occurred in
the U.S. since 1999?
Over 3 Million!!!
What disease vector
ranks #1 in pathogen
diversity?
Ticks
Emergence/Resurgence of Vector-
• Pesticide Borne Diseases
• resistance
Decreased resources for surveillance,
prevention and control
• Deterioration of public health infrastructure
• Unprecedented population growth
• Uncontrolled urbanization
• Changes in agricultural practices
• Deforestation
• Increased travel
*Encyclopedia of Public
Health
Vecto
r
Transmitters of disease-
causing organisms that
carry a pathogen from one
host to another
Vector-Borne Disease
Transmission
Biological
• Most significant mode of transmission
- Arthropod ingests a pathogen while taking a
blood meal from an infected host
- Pathogen multiplies within the arthropod
(reservoir)
- Pathogen is transmitted to another host
when arthropod takes another blood
meal
Vector-Borne Disease
Transmission
Mechanical
• Vector physically carries pathogens from
one place or host to another, usually on
body parts or through the gastrointestinal
tract
Mosquito-Borne
Disease
Clinical spectrum of human WNV infections
~ 1% ~ 10% of WNND are fatal
WNND = West Nile WNND
Neuroinvasive Disease:
Meningitis,
Encephalitis, 1 WNND case =
Acute Flacid Paralysis 20 - 30% 140 - 250 infections
“West Nile Fever”
70 - 80%
Asymptomatic – Inapparent
WNV: Long-Term Outcomes
• WN Encephalitis and WN Fever
– Persistent disabling neurologic sequelae
common
– Tremors, movement disorders, cognitive
problems in >50%
– 8 published studies show complaints frequently
persist >1 year post infection (Some > 3
years)
– Fatigue, pain, subjective memory / concentration
problems
– Higher all-cause mortality rates >1 year post-
infection
*# Sejvar et al., J Neuropsychol 2008; ^Greenberg et al., EID
2005
WNV Human Cases 1999-
2012*
Year
16,045 WNND Cases
WNND
Cases
Fever
Cases
Total
cases
1999 59 3 62 x 140 Infections/WNND
2000 19 2 21
2001 64 2 66 ~ 2.24 million infections
2002 2946 1210 4156
2003 2866 6996 9862
16,045 WNND Cases
2004 1148 1391 2539
x 250 Infections/WNND
2005 1309 1691 3000
2006 1495 2761 4256 ~ 4.01 million infections
2007 1227 2371 3598
2008 689 667
1356 U.S. Population 311M
2009 386 334 720
Estimate 0.7% - 1.2% of population
2010 629 392 1021
2011 474 216 690
infected with WNV
2012 2734 2653 5387
Total
* data 16,045
as of 12/11/2012 20,689 36,734
West Nile Virus Total (Neuroinvasive and
Fever) Cases Reported in the United States
1999-2012*
WNND Cases Fever
Cases
10000
9000
Number of Cases
8000
7000
6000
5000
4000
3000
2000
1000
0
1999
2000
2001
2002
2003
2004
2005
2006
2007
2008
2009
2010
2012
2011
* data as of 12/11/2012
West Nile virus neuroinvasive disease incidence reported to ArboNET,
by state, United States, 2014
Source: ArboNET, Arboviral Diseases Branch, Centers for Disease Control and Prevention
West Nile virus cases incidence reported to ArboNET, by county, United
States, as of August 20, 2014
West Nile Virus Neuroinvasive Disease Incidence by State – United States,
2015 (as of January 12, 2016)
Source: ArboNET, Arboviral Diseases Branch, Centers for Disease Control and Prevention
West Nile Virus Disease Cases by State – United States, 2014
Non- Total
State Neuroinvasive Neuroinvasive Cases Deaths*
Arizona 80 27 107 13
Nevada 3 0 3 0
New Mexico 19 5 24 1
California 138
Nevada 1
New Mexico 3
Texas 32
Hawaii 19
Locally Acquired Dengue
Human Cases – US 2015
State Local Cases
Arizona 0
California 0
Nevada 0
New Mexico 0
Texas 0
Hawaii 200
Chikungunya Virus (CHIKV)
• Mosquito-borne alphavirus
3
Chikungunya Transmission Cycles
3
Chikungunya Virus Disease
• Characterized by acute onset of fever and severe polyarthralgia
• Acute symptoms typically resolve in 7‒10 days
• Mortality is rare; occurs mostly in older adults
• Variable proportions of patients report:
• Relapse of rheumatologic symptoms* in the months following
acute illness
• Persistent joint pains for months or years
California 275
Nevada 1
New Mexico 0
Texas 54
Hawaii 7
Locally Acquired Chikungunya
Human Cases – US 2015
State Local Cases
Arizona 0
California 0
Nevada 0
New Mexico 0
Texas 0
Hawaii 0
Zika virus disease (Zika)
• Disease spread primarily through the
bite of an infected Aedes mosquito.
• Many people infected with Zika virus
won’t have symptoms or will only
have mild symptoms.
• However, Zika can cause birth
defects and other problems such as
stillbirth and
miscarriage.
Zika
• Zika can be spread
through:
• Mosquito bites
• Aedes
US States* US Territories
• 1657 travel-associated cases† 21 travel-associated cases†
• 0 locally transmitted cases‡ 4729 locally transmitted cases‡
California 87
Nevada 11
New Mexico 3
Texas 76
Hawaii 10
Zika
199 201
6 4
2012 – Texas, 33 cases
2012 – Pennsylvania,
4146 cases
Lyme Disease
Roof
Rat
Hous
e
Mous
e
ECONOMIC IMPORTANCE
• Rats in the human environment
cause enormous economic loss
- Consume and contaminate
vast quantities of food
- Cause fires by gnawing the
insulation from electric wires
• Commensal rodents cost billions
of dollars each year in the United
States.
-Internal destruction to
computers and other sensitive
equipment
-Structural damage to
homes and businesses
Human Health Impact
Human Health Impact
RODENT-BORNE DISEASES
• Rats and mice spread diseases in
two distinct ways.
– Directly - by contamination of food, water and
air with their urine and feces
– Indirectly – by way of rodent fleas, ticks and
mites Direct Indirect
• Rat bite Plague
fever Murine
• Salmonellos typhus
is Scrub
• Leptospirosi
typhus
s
Tularemia
• Hantavirus
Bed
• Resurgence of a pest health
Bugs
departments have not dealt with
in over 50 years.
Why are they
back?
Greater international and domestic
travel
Lack of knowledge regarding
control of bed bugs due to their
prolonged absence
Increased resistance to
available pesticides
The continuing decline s or
.
elimination of effective vector/pest
control programs at state and local
Photo courtesy of Dr. Harold Harlan, Armed Forces
Pest Management Board Image Library (
• Harborag
e
• Water IPM
Water Harbor
• Life -age
Cycle
CONTROLING MOSQUITOES
Understanding the Mosquito Life-
Cycle
Egg Larva
s e
Pupa
e
Adul
t
CONTROLING MOSQUITOES
Understanding Mosquito
Breeding Habitats
CONTROLING MOSQUITOES
Understanding Mosquito
Breeding Habitats
CONTROLING MOSQUITOES
Monitoring
and
Surveillance
CONTROLING MOSQUITOES
Source
Reduction
CONTROLING MOSQUITOES
Adulticide
CONTROLING MOSQUITOES
Oils
• Suffocation – mechanical barrier at
surface
• Poisoning due to toxic properties
of the volatiles
CONTROLING MOSQUITOES
Larvicides
CONTROLING MOSQUITOES
Preventing Mosquito
Bites
Cover Up
CONTROLING MOSQUITOES
Preventing Mosquito
Bites
Use Repellent
• Use
Environmental
Protection
Agency (EPA)-
registered insect
repellents.
• DEET, picaridin,
IR535, or oil of
lemon eucalyptus
or
CONTROLING MOSQUITOES
Preventing Mosquito
Bites Use Repellent
For babies and children
• Do not apply onto
hands, eyes, mouth,
and cut or irritated
skin.
• Adults: Spray onto
your hands and then
apply to a child’s face.
• Do not use insect
repellent on babies
younger than 2 months
Controling Zika Infection
CONTROLING TICKS
• Repellents
• EPA-Approved
Products
• DEET, Picaridin, Oil
of Eucalyptus
• Clothing Applications
• Permethrin
• Tick-Checks
• Light-colored clothing
CONTROLING TICKS
Removing
Ticks
CONTROLING TICKS
Managing
Habitat
CONTROLING TICKS
Managing
Hosts
CONTROLING RATS
Recognizing the
Signs
Gnawin Rub
g Mark
s
CONTROLING RATS
Recognizing the
Signs
Dropping Sightings,
s Odors, Sounds
CONTROLING RATS
Recognizing the
Signs
Burrows
CONTROLING RATS
• Remove Harborage – No Place to
Live!
• Clean-Up
• Sanitation
CONTROLING RATS
• Prevent
Entry –
Keep Them
Out!
CONTROLING RATS
• Prevent
Entry –
Keep Them
Out!
CONTROLING RATS
• Prevent Entry
– No Place To
Live!
CONTROLING RATS
• CDC EOC
• Zika
WHAT RESOURCES ARE AVAILABLE?
CDC NCEH
• www.cdc.gov • Environmental Health
• CDC A-Z Index Services Branch
• Communication Tools • EH Workforce
• Materials for: Development/Traini
• Providers ng
• Parents • VCEHP Online
• Churches Course
• Daycares • Prevention Tools
• Housing/Lodging • IPM
• Infographics and Posters
• Technical Support
• Information, Education,
and Guidance
Articles, Links
• Needs/Gaps
• Disease and Vector Info
Identification
• PREVENTION
• NEHA
• Tools/Resources/
Training
DO YOU HAVE ANY ADVICE
FOR
Understanding Vectors TRIBESand
Education ON THIS TOPIC?
Outreach
• Biology an d Ecology • Community Members
• What/When/Where • Schools
• Complete Life Cycles • Healthcare Providers
• Vector
Identification • Communication Tools
Total population
~10,000 persons
97 cases and 10
deaths in 8 years
10.3% case- fatality
rate
The San Carlos Situation, cont.
The project area
• 600 households
• Estimated 1,000 dogs
(66% free-roaming)
• 2 deaths in Spring,
2012
• No permanent vet
services
• Animal control
recently established
• Motivated community
The RMSF Rodeo: 2012-2013
Goal: Improve human health
by improving the health
of dogs
PHASE I: control
• Monthly yard treatments
• Long-lasting tick collars
on all dogs
PHASE II: sustainability
• Prove tick control
can be maintained with
collars alone
The RMSF Rodeo Plan: Properly
Timed Pesticide Treatments
May June
Once a Summer
Once a Summer
July August
Yard Treatment
Bayer Ready To Spray Product
• Beta cyfluthrin spray
3 Gallon Sprayers
• Spray around the house
• Spray dog areas
ATVs
The RMSF Rodeo Plan: Improve Dog
Health
Place a long-acting tick collar
on every dog in a community
Encourage spay/neuter for
population control
Identify and remove strays Water
Improved care and ownership
• Tag, collar Food
• Restrain pets (via fence or Shade
tether)
Long-acting Tick Collars
Seresto ®
• 4.5% Flumethrin, 10% imidacloprid
• Visible marker of treatment
• 8 months of efficacy
Other tick control products may be
used
• Consider how often they need
to be reapplied
RMSF Rodeo Results: Tick Counts on
Dogs
Expected level of ticks without intervention
60%
40%
30%
20%
10%
0%
Phase I Phase II
RMSF Rodeo Results:
Environmental Burden
1400
Number of ticks observed 1200
1000
800
600
400
200
0
May 2012 June 2012 July 2012 Early Late March May 2013
August August 2013
2012 2012
Adults Nymphs Larv
ae
RMSF Rodeo Results: Human
Incidence of Rickettsia rickettsii
1.40
1.24 1.24
Human incidence
decreased 40%
Average cases per 1000 persons
1.20
1.00 0.90
0.80 0.71
0.60
0.40
0.20
0.00
Before start of RMSF Rodeo After start of RMSF Rodeo
Non-Rodeo Rodeo
Includes surveillance data 2 years prior to start of RMSF Rodeo, and 2 years after
RMSF Rodeo Partners
Keys to Effective RMSF Control
Controlling Ticks: Treat dogs with tick collars, and
yards with routinely applied pesticides
Maintaining Low Levels of Ticks: Once ticks are
controlled, maintaining low tick levels with collars
alone. Monitor levels and apply pesticide if needed.
Improving Pet Health: Introduce regular
spay/neuter programs, encourage pet restraint, and
identify and remove strays
Establishing Programs: Hire staff, purchase
permanent equipment
Other Tribal RMSF Prevention Efforts
Tohono O’odham Nation
Hopi Tribe
Gila River Indian Community
Many more…
Things to Consider
Scope of intervention needed
• Total population or targeted approach?
Current resources
• Personnel
• Animal control
• Monetary
Product selection
• Over the counter or restricted use?
• Water quality or agricultural restrictions?
• Period of efficacy
• Cost
Documenting progress
Addressing Sustainability
Affected tribes working to implement prevention
programs based on lessons learned in RMSF Rodeo
IHS emergency funds awarded to Arizona tribes for
RMSF prevention
Other public and private grants available
Naomi Drexler
[email protected]
Fabiola Estrada
Patti TenBrook
Land Division
US EPA R9
Overview
Integrated Pest Management
(IPM)
Pesticides and
Response to Zika
Resources
What is IPM?
Low
Commo Better impact
Long-
n- understandi on
term ng
human
sense
solution of pests health &
strateg
s the
y
environme
nt
Identif
y
Pest
Monitor
Assess and
the Effect Assess
of Pest Numbers
Manageme and
nt Damage
IPM
Practice
s and
Principle
s Guidelines
Pest
Manageme for
nt Manageme
nt Action
tools
Preventi
on of
Pest
Problems
Interventi
on
Preventio
n EDUCATION/SANITATION
What is a Pesticide?
A pesticide is any
substance "intended
for preventing,
destroying, repelling,
or mitigating any
pest....”
Pesticide Safety
Pesticide
Use
Pesticide Risk
Aging Compromis
Population ed
Immune
s Systems
Exposure Toxicity
RIS
K
Pregnan
Childre
t
Wome n
n 17
1
IPM
for
Ve c t o r s
P
hysical
Public Information and Education
Protect Yourself and Others
• Long Sleeves/Pants
• EPA-registered Repellents
• Window/Door Screens, Nets, A/C
• Media
campaign/coverage.
• Participation in
community events.
• A comprehensive
school program
Mosquito Vector Surveillance
Collect and analyze data on
abundance mosquito populations.
Minimize emergent
vegetation and surface debris
on the water.
Biological
Gambusia affinis (Mosquito
fish)
Microbial and Chemical
Adulticid
es
Know Your Pest
Daytime Nighttime
biters biters
Tropics/Southern Throughout
US US
Know Your Pest
Aedes Culex
aegypti tarsalis
Aedes Culex
albopictus pipiens
EPA’s Role in Zika
Response
Provide Pest Tire/Trash Cleanup
Management Tools
Suppo
rt Registered
Products
Factsheets
Insect
Repellent
Search Tool
https://www.epa.gov/insect-repellents/find-insect-repellent-right-
you#search tool
Repellency Awareness Graphic
RESOURCES
Centers for Disease Control
http://www.cdc.gov/zika/prevention/inde
x.html
ON Sebastian
Beshk Jenny
Stephenson
Shannon Davis
Causes of Illegal
Dumping
• Convenience
• Cost
• Lack of Information
• Past Practice (i.e. routine)
• No Solid Waste Plan or
infrastructure
• No codes nor enforcement
Developing a prevention +
enforcement program
Communi Develo
Understa
ty p
nd Support Strate
gy
Step 1: Understand the
problem
• Tools:
• Some tribes have
Door-to-door survey used their
• Hold a community Environmental staff
gathering to conduct surveys
• Survey the dumpsites to their local
community.
One tribe found that
people were using
the illegal dumpsites
because they did not
know it was unsafe
and illegal!
Step 2: Gain Tribal + Community
Support
• Tools:
• Maps
• Pictures
• Press coverage
• Tours
• Explanation of
cost
Step 3: Choose your
strategy
We’ll cover more on this topic in the following
slides, but keep in mind how the selected
strategy/strategies…
• Reflects the values and goals of the tribe
• Provides for tribal control and sovereignty
• Involves tribal government and community members
• Builds on local knowledge, experience and expertise
• Allows for continuous feedback including a complaint mechanism
(!)
• Is feasible
NON-
ENFORCEME
NT
What you can
MEASURES
do…
Overvie
w
• • Barriers
Community Outreach
and Education • Hotlines
• Cleanup
• Rewards
• Dump Tracking • Monitoringand
• Posting Signs Surveillance
• Lighting Cameras
Community Outreach +
Education
Outreach and education
may include:
• Press releases
• Publicity photographs
• Outreach materials
• Public hotline
• Presentations
• Cleanup days
Choose Measur
your e
approac
h
• Strategy
for
Enforcement
• Resources
Illegal Dumping
Codes
Components to Illegal
Dumping Codes Tribes have
• Dumping Code Purpose extensive
• Dumping Definition authority to
create illegal
• Dumping Sanctions dumping
• Dumping Enforcement Responsibility codes!
• Dumping Adjudicative Responsibility
Sample Language-
Hopi
Purpose Definition
“2.1. The open dumping and open “6.1. It shall be unlawful for
burning of solid wastes shows any person … to dump,
disrespect for the natural scatter, or place, or cause to
resources of the Reservation, and be dumped, scattered or
for the Reservation community; it placed any solid waste
causes irreparable damage to the
material, hazardous or
land and the environment; it is a
not . . . .”
threat to the health and safety of
Hopland residents.”
Sample Language-
Hopi
Sanctions Common Sanctions
“9.1. Any person who violates any Include
• Fines
of the provisions of this Code is
subject to an assessment of civil • Legal action against
damages for such unlawful property owners
activities.... Any person who is • Property seizure and
found by the court to have vehicle
impoundment
committed the alleged violations
• Community service
shall be subject to … a civil
penalty in an amount up to • Court-ordered cleanup
$500.00 dollars for each day of and
GAP AND
VECTORS
HOW TO USE THE
GENERAL ASSISTANCE PROGRAM
• Training
• How to write plans, and develop programs for Vector
Management
• Pesticides Management
• Integrated Waste Management
• Writing Ordinances
• And MORE!
PLANNING AND
DEVELOPING PROGRAMS
• Planning
• Integrated Solid Waste Management
Plans
• Integrated Pesticide Management
Plans
• ETEPs
• Environmental Inventories
• Emergency Response Plans
OUTREACH AND EDUCATION
1. Program Administration
2. Compliance and Enforcement
3. Solid Waste Management, Resource
Recovery, and Resource Conservation
Support
4. Cleanup and Closure
HOW CAN THAT HELP IN
VECTOR- BORNE DISEASE
MANAGEMENT?
• Program Administration
• Ensuring that the tribe has a Solid Waste Program in place to do all the
activities we will describe:
• Resource Recovery
• Community Clean-Ups
• White Good Clean Ups
• Special Clean up Days for Elders
• Clean up of Tire Piles
WHAT ABOUT CLEANUP AND CLOSURE?