Suicide is defined as intentionally taking one's own life. Depression is often a main cause, as one feels pain exceeds their ability to cope. Warning signs of suicide include depression, talking about death, changes in behavior or mood, and a strong sense of hopelessness. A survey found most respondents knew someone who considered or attempted suicide, and many had experienced depression themselves. The document relates suicide to the themes in the book "Twisted", where a character considers suicide due to feeling uncared for by others.