François Courtois provides 10 design guidelines to reduce cart abandonment based on research findings: 1) Make product pages compelling, 2) Optimize navigation, 3) Use clear calls to action, 4) Consider loading times, 5) Build trust with customer service, 6) Let customers find stores easily, 7) Streamline checkout, 8) Support multi-channel experiences, 9) Clarify value on landing pages, and 10) Work with affiliate publishers to re-engage customers. The document includes research statistics to support each guideline and notes on implementation.